Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Susanne Schneiker"'
Autor:
Laura Schlüter, Tobias Busche, Laila Bondzio, Andreas Hütten, Karsten Niehaus, Susanne Schneiker-Bekel, Alfred Pühler, Jörn Kalinowski
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1241 (2024)
Sigma factors are transcriptional regulators that are part of complex regulatory networks for major cellular processes, as well as for growth phase-dependent regulation and stress response. Actinoplanes sp. SE50/110 is the natural producer of acarbos
Externí odkaz:
https://doaj.org/article/b101982408124d9394f1347f00c884b6
Autor:
Sophia Nölting, Camilla März, Lucas Jacob, Marcus Persicke, Susanne Schneiker-Bekel, Jörn Kalinowski
Publikováno v:
Microorganisms, Vol 11, Iss 4, p 848 (2023)
The pseudo-tetrasaccharide acarbose, produced by Actinoplanes sp. SE50/110, is a α-glucosidase inhibitor used for treatment of type 2 diabetes patients. In industrial production of acarbose, by-products play a relevant role that complicates the puri
Externí odkaz:
https://doaj.org/article/f793338eaace44ff9fc49240bc2f8a25
Autor:
Lena Schaffert, Camilla März, Lisa Burkhardt, Julian Droste, David Brandt, Tobias Busche, Winfried Rosen, Susanne Schneiker-Bekel, Marcus Persicke, Alfred Pühler, Jörn Kalinowski
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Background Actinoplanes sp. SE50/110 is a natural producer of acarbose. It has been extensively studied in the last decades, which has led to the comprehensive analysis of the whole genome, transcriptome and proteome. First genetic and micro
Externí odkaz:
https://doaj.org/article/06fc22940a8d490ea4714e557b6cfb5e
Autor:
Timo Wolf, Julian Droste, Tetiana Gren, Vera Ortseifen, Susanne Schneiker-Bekel, Till Zemke, Alfred Pühler, Jörn Kalinowski
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Acarbose is used in the treatment of diabetes mellitus type II and is produced by Actinoplanes sp. SE50/110. Although the biosynthesis of acarbose has been intensively studied, profound knowledge about transcription factors involv
Externí odkaz:
https://doaj.org/article/90a21bf5be4f444882987be5ac13cdde
Autor:
Lena Schaffert, Susanne Schneiker-Bekel, Saskia Dymek, Julian Droste, Marcus Persicke, Tobias Busche, David Brandt, Alfred Pühler, Jörn Kalinowski
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Actinoplanes sp. SE50/110 is the wild type of industrial production strains of the fine-chemical acarbose (acarviosyl-maltose), which is used as α-glucosidase inhibitor in the treatment of type II diabetes. Although maltose is an important building
Externí odkaz:
https://doaj.org/article/776f825ee4b74dc48d0e327737eceb89
Autor:
José-María Vinardell, Sebastián Acosta-Jurado, Susanne Zehner, Michael Göttfert, Anke Becker, Irene Baena, Jochem Blom, Juan Carlos Crespo-Rivas, Alexander Goesmann, Sebastian Jaenicke, Elizaveta Krol, Matthew McIntosh, Isabel Margaret, Francisco Pérez-Montaño, Susanne Schneiker-Bekel, Javier Serranía, Rafael Szczepanowski, Ana-María Buendía, Javier Lloret, Ildefonso Bonilla, Alfred Pühler, José-Enrique Ruiz-Sainz, Stefan Weidner
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 28, Iss 7, Pp 811-824 (2015)
Sinorhizobium fredii HH103 is a fast-growing rhizobial strain infecting a broad range of legumes including both American and Asiatic soybeans. In this work, we present the sequencing and annotation of the HH103 genome (7.25 Mb), consisting of one chr
Externí odkaz:
https://doaj.org/article/1f0be0ce38994ab6a8193a17d4c7f4be
Autor:
Lena Schaffert, Julian Droste, Alfred Pühler, Susanne Schneiker-Bekel, Timo Wolf, Martin Kulisch, Jörn Kalinowski
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Actinoplanes sp. SE50/110 is the industrially relevant producer of acarbose, which is used in the treatment of diabetes mellitus. Recent studies elucidated the expression dynamics in Actinoplanes sp. SE50/110 during growth. From these data,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c429e7b6729d4bf10dd2a564720977d1
https://doi.org/10.1007/s00253-020-10923-2
https://doi.org/10.1007/s00253-020-10923-2
Autor:
Jessica Gierhake, Julian Droste, Alfred Pühler, Susanne Schneiker-Bekel, Lena Schaffert, Jörn Kalinowski, Marcus Persicke, Winfried Dipl Chem Dr Rosen
Publikováno v:
Applied Microbiology and Biotechnology
Actinoplanes sp. SE50/110 (ATCC 31044) is the wild type of industrial producer strains of acarbose. Acarbose has been used since the early 1990s as an inhibitor of intestinal human α-glucosidases in the medical treatment of type II diabetes mellitus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d506a25e60a8fd60a2da636dba7b2bb
http://europepmc.org/articles/PMC7275007
http://europepmc.org/articles/PMC7275007
Autor:
Julian Droste, Vera Ortseifen, Lena Schaffert, Marcus Persicke, Susanne Schneiker-Bekel, Alfred Pühler, Jörn Kalinowski
Background: Actinoplanes sp. SE50/110 is the natural producer of the diabetes mellitus drug acarbose, which is highly produced during the growth phase and ceases during the stationary phase. In previous works, the growth-dependency of acarbose format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36493c21d023986b7726c5c444623ab
https://doi.org/10.21203/rs.3.rs-41287/v2
https://doi.org/10.21203/rs.3.rs-41287/v2
Autor:
Lena, Schaffert, Lucas, Jacob, Susanne, Schneiker-Bekel, Marcus, Persicke, Camilla, März, Christian, Rückert, Alfred, Pühler, Jörn, Kalinowski
Publikováno v:
Microbiology resource announcements. 9(39)
The pSETT4 vector integrates into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ef8f6dff54f687f76c67fa6f7307550
https://pubmed.ncbi.nlm.nih.gov/32972929
https://pubmed.ncbi.nlm.nih.gov/32972929