Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Susanne P. Pallo"'
Publikováno v:
Neurobiology of Aging. 63:128-139
During aging, decreased efficiency of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activation and autophagic processes in the brain may be a contributing factor in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease. Ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97bee356c8e74b5dd7e9c1b0ae13d851
https://doi.org/10.1016/j.neurobiolaging.2017.12.001
https://doi.org/10.1016/j.neurobiolaging.2017.12.001
Publikováno v:
Brain Research. 1634:119-131
Excitotoxicity was originally postulated to be a late stage side effect of Alzheimer׳s disease (AD)-related neurodegeneration, however more recent studies indicate that it may occur early in AD and contribute to the neurodegenerative process. Tau an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e249fd069ecc282ea7660af5141a6b3
https://doi.org/10.1016/j.brainres.2015.12.048
https://doi.org/10.1016/j.brainres.2015.12.048
Autor:
Gail V.W. Johnson, Susanne P. Pallo
Publikováno v:
Neuroscience letters. 597
Alzheimer’s disease (AD) is defined by presence of two pathological hallmarks, the intraneuronal neurofibrillary tangle (NFT) formed by abnormally processed tau, and the extracellular amyloid plaques formed primarily by the amyloid beta peptide (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3546dda37a7e1802e8cb8cb465750dc1
https://pubmed.ncbi.nlm.nih.gov/25888814
https://pubmed.ncbi.nlm.nih.gov/25888814