Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Susanne Nikolaus"'
Autor:
Owen Y. Chao, Salil S. Pathak, Hao Zhang, Nathan Dunaway, Jay-Shake Li, Claudia Mattern, Susanne Nikolaus, Joseph P. Huston, Yi-Mei Yang
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract The dopamine (DA) system has a profound impact on reward-motivated behavior and is critically involved in neurodevelopmental disorders, such as autism spectrum disorder (ASD). Although DA defects are found in autistic patients, it is not wel
Externí odkaz:
https://doaj.org/article/8c7c8b2c11bf46c996a63dea1d8651a5
Autor:
Susanne Nikolaus, Hans-Jörg Wittsack, Christina Antke, Markus Beu, Hubertus Hautzel, Cvetana Decheva, Eduards Mamlins, Yuriko Mori, Joseph P. Huston, Gerald Antoch, Hans-Wilhelm Müller
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Purpose: The 5-HT2A receptor (R) is known to modulate dopamine (DA) release in the mammalian brain. Altanserin (ALT) and 2,5-dimethoxy-4-iodoamphetamine (DOI) act as 5-HT2AR antagonist and agonist, respectively. In the present study, we assessed the
Externí odkaz:
https://doaj.org/article/924d4bbe6b6649778627c980bb761157
Autor:
Susanne Nikolaus, Hans-Jörg Wittsack, Markus Beu, Christina Antke, Maria A. De Souza Silva, Frijthof Wickrath, Anja Müller-Lutz, Joseph P. Huston, Gerald Antoch, Hans-Wilhelm Müller, Hubertus Hautzel
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Purpose: The present study assessed the effects of the GABAA receptor (R) agonist muscimol (MUS), and the GABAAR antagonist bicuculline (BIC) on neocortical and subcortical radioligand binding to dopamine D2/3Rs in relation to motor and exploratory b
Externí odkaz:
https://doaj.org/article/189a1d6f30594548a954aa83ddc9b471
Autor:
An-Li, Wang, Owen Y, Chao, Susanne, Nikolaus, Valeria, Lamounier-Zepter, Cornelis P, Hollenberg, Gert, Lubec, Svenja V, Trossbach, Carsten, Korth, Joseph P, Huston
Publikováno v:
Neuroscience. 493:41-51
Alterations in cognitive functions, social behaviors and stress reactions are commonly diagnosed in chronic mental illnesses (CMI). Animal models expressing mutant genes associated to CMI represent either rare mutations or those contributing only min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5630d29a5b8fb501964beef91d1c2f93
https://doi.org/10.1016/j.neuroscience.2022.04.013
https://doi.org/10.1016/j.neuroscience.2022.04.013
Autor:
Susanne Nikolaus, Eduards Mamlins, Christina Antke, Mardjan Dabir, Hans-Wilhelm Müller, Frederik L. Giesel
Publikováno v:
Reviews in the Neurosciences. 33:859-876
The precise cortical and subcortical mechanisms of Tourette syndrome (TS) are still not fully understood. In the present retrospective analysis, adolescent and adult medication-naïve patients showed increased DA transporter (DAT) binding in nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a20d3c4f9bbcc9913e2504a74b7058cc
https://doi.org/10.1515/revneuro-2022-0035
https://doi.org/10.1515/revneuro-2022-0035
Publikováno v:
Neuroscience and biobehavioral reviews. 141
Rats and mice are used for studying neuronal circuits underlying recognition memory due to their ability to spontaneously remember the occurrence of an object, its place and an association of the object and place in a particular environment. A joint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddd8fbd84b48952ca3be75b1f08f60a
https://pubmed.ncbi.nlm.nih.gov/36089106
https://pubmed.ncbi.nlm.nih.gov/36089106
Autor:
Susanne, Nikolaus, Hans-Jörg, Wittsack, Markus, Beu, Hubertus, Hautzel, Christina, Antke, Eduards, Mamlins, Jens, Cardinale, Cvetana, Decheva, Joseph P, Huston, Gerald, Antoch, Frederik L, Giesel, Hans-Wilhelm, Müller
Publikováno v:
Pharmacology, biochemistry, and behavior. 215
Serotonin(5-HT)ergic projections run from the raphe nuclei to dopamin(DA)ergic cells in substantia nigra/ventral tegmental area (SN/VTA) and to the terminal fields of DA neurons in nucleus accumbens, caudateputamen and neocortex. In the present studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0cd39095e41260087997836a063324fd
https://pubmed.ncbi.nlm.nih.gov/35227734
https://pubmed.ncbi.nlm.nih.gov/35227734
Publikováno v:
Reviews in the neurosciencesReferences. 33(4)
Disturbances of dopamine (DA), serotonin (5-HT) and/or norepinephrine (NE) functions are implied in attention-deficit hyperactivity disorder (ADHD). However, the precise cortical and subcortical mechanisms are still not fully understood. In the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc21bf540c3f451204a3aae28160d4a
https://pubmed.ncbi.nlm.nih.gov/34378877
https://pubmed.ncbi.nlm.nih.gov/34378877
Autor:
Hans-Wilhelm Müller, Joseph P. Huston, Susanne Nikolaus, Hans-Jörg Wittsack, Frithjof Wickrath, Markus Beu, Eduards Mamlins, Maria A. de Souza Silva, Christina Antke, Anja Müller-Lutz, Hubertus Hautzel, Gerald Antoch
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
D-cycloserine (DCS) and amantadine (AMA) act as partial NMDA receptor (R) agonist and antagonist, respectively. In the present study, we compared the effects of DCS and AMA on dopamine D2/3R binding in the brain of adult rats in relation to motor beh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9d37b1c0492bf57022c0b66a081ed2
http://link.springer.com/article/10.1038/s41598-019-52185-7
http://link.springer.com/article/10.1038/s41598-019-52185-7
Autor:
Joseph P. Huston, Maria A. de Souza Silva, Christina Antke, Anja Müller-Lutz, Markus Beu, Hans-Jörg Wittsack, Hans-Wilhelm Müller, Hubertus Hautzel, Susanne Nikolaus, Frithjof Wickrath, Gerald Antoch
Publikováno v:
Pharmacology Biochemistry and Behavior. 179:156-170
Purpose The present study assessed the influence of the NMDA receptor (R) antagonist amantadine (AMA) on cerebral dopamine D2/3R binding in relation to motor and exploratory activity in the rat. Methods D2/3R binding was determined in anaesthetized a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738aef0cad8d8842f730f70bb62711e0
https://doi.org/10.1016/j.pbb.2018.12.010
https://doi.org/10.1016/j.pbb.2018.12.010