Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Susanne Meile"'
Autor:
Jiemin Du, Susanne Meile, Jasmin Baggenstos, Tobias Jäggi, Pietro Piffaretti, Laura Hunold, Cassandra I. Matter, Lorenz Leitner, Thomas M. Kessler, Martin J. Loessner, Samuel Kilcher, Matthew Dunne
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Bacteriophages operate via pathogen-specific mechanisms of action distinct from conventional, broad-spectrum antibiotics and are emerging as promising alternative antimicrobials. However, phage-mediated killing is often limited by bacterial
Externí odkaz:
https://doaj.org/article/15efe631889b4075b2703227b046234f
Autor:
Susanne Meile, Jiemin Du, Samuel Staubli, Sebastian Grossmann, Hendrik Koliwer-Brandl, Pietro Piffaretti, Lorenz Leitner, Cassandra I. Matter, Jasmin Baggenstos, Laura Hunold, Sonja Milek, Christian Guebeli, Marko Kozomara-Hocke, Vera Neumeier, Angela Botteon, Jochen Klumpp, Jonas Marschall, Shawna McCallin, Reinhard Zbinden, Thomas M. Kessler, Martin J. Loessner, Matthew Dunne, Samuel Kilcher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The rapid detection and species-level differentiation of bacterial pathogens facilitates antibiotic stewardship and improves disease management. Here, we develop a rapid bacteriophage-based diagnostic assay to detect the most prevalent patho
Externí odkaz:
https://doaj.org/article/380bf3f0f3d44554830c4469d686c355
Autor:
Anna M. Sobieraj, Markus Huemer, Léa V. Zinsli, Susanne Meile, Anja P. Keller, Christian Röhrig, Fritz Eichenseher, Yang Shen, Annelies S. Zinkernagel, Martin J. Loessner, Mathias Schmelcher
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Staphylococcus aureus is a human pathogen causing life-threatening diseases. The increasing prevalence of multidrug-resistant S. aureus infections is a global health concern, requiring development of novel therapeutic options. Peptidoglycan-
Externí odkaz:
https://doaj.org/article/db6d42fc26334af090638c286d488157
Publikováno v:
Viruses, Vol 12, Iss 9, p 944 (2020)
Fast and reliable detection of bacterial pathogens in clinical samples, contaminated food products, and water supplies can drastically improve clinical outcomes and reduce the socio-economic impact of disease. As natural predators of bacteria, bacter
Externí odkaz:
https://doaj.org/article/5c7e9fdc9a30470abd2e54cd3071372a
Autor:
Jan C. Wohlfarth, Miki Feldmüller, Alissa Schneller, Samuel Kilcher, Marco Burkolter, Susanne Meile, Martin Pilhofer, Markus Schuppler, Martin J. Loessner
Publikováno v:
Nature Microbiology, 8 (3)
At the end of a lytic bacteriophage replication cycle in Gram-positive bacteria, peptidoglycan-degrading endolysins that cause explosive cell lysis of the host can also attack non-infected bystander cells. Here we show that in osmotically stabilized
Autor:
Susanne Meile, Jiemin Du, Samuel Staubli, Sebastian Grossman, Hendrik Koliwer-Brandl, Pietro Piffaretti, Lorenz Leitner, Cassandra I. Matter, Jasmin Baggenstos, Laura Hunold, Sonja Milek, Christian Gübeli, Marko Kozomara-Hocke, Vera Neumeier, Angela Botteon, Jochen Klumpp, Jonas Marschall, Shawna McCallin, Reinhard Zbinden, Thomas M. Kessler, Martin J. Loessner, Matthew Dunne, Samuel Kilcher
The rapid detection and species-level differentiation of bacterial pathogens facilitates antibiotic stewardship and improves disease management. Here, we develop a rapid bacteriophage-based diagnostic assay to detect the most prevalent pathogens caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3be2c4cfae4c1744b7a2b63e0d1bfee
https://doi.org/10.1101/2022.11.23.517494
https://doi.org/10.1101/2022.11.23.517494
Autor:
Lorenz Leitner, Jiemin Du, Susanne Meile, Shawna McCallin, Vera Neumeier, Thomas M. Kessler, Martin J. Loessner, Samuel Kilcher, Matthew Dunne
Publikováno v:
Journal of Urology. 207
Autor:
Jiemin Du, Susanne Meile, Jasmin Baggenstos, Tobias Jäggi, Pietro Piffaretti, Laura Hunold, Cassandra I. Matter, Lorenz Leitner, Thomas M. Kessler, Martin J. Loessner, Samuel Kilcher, Matthew Dunne
Bacteriophages operate via pathogen-specific mechanisms of action distinct from conventional, broad-spectrum antibiotics and are emerging as promising alternatives. However, phage-mediated killing is often limited by bacterial resistance development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ac3b9aba522c95d74a448188a7a5e10
https://doi.org/10.1101/2022.03.09.483629
https://doi.org/10.1101/2022.03.09.483629
Publikováno v:
Current Opinion in Virology, 52
The alarming rise in antimicrobial resistance coupled with a lack of innovation in antibiotics has renewed interest in the development of alternative therapies to combat bacterial infections. Despite phage therapy demonstrating success in various ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f2ab86d67a933e1cfc648da006c383
Autor:
Annelies S. Zinkernagel, Anja P. Keller, Yang Shen, Markus Huemer, Susanne Meile, Anna M. Sobieraj, Christian Röhrig, Mathias Schmelcher, Fritz Eichenseher, Léa V. Zinsli, Martin J. Loessner
Publikováno v:
mBio, 11 (5)
mBio
mBio, Vol 11, Iss 5 (2020)
mBio
mBio, Vol 11, Iss 5 (2020)
Life-threatening infections with Staphylococcus aureus are often difficult to treat due to the increasing prevalence of antibiotic-resistant bacteria and their ability to persist in protected niches in the body. Bacteriolytic enzymes are promising ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfd835360107314297b425530d9974c
https://www.zora.uzh.ch/id/eprint/191107/
https://www.zora.uzh.ch/id/eprint/191107/