Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Susanne M, Picker"'
Autor:
Susanne M. Picker
Publikováno v:
Journal of Cardiovascular Pharmacology. 61:166-174
Blood platelets (PLTs) play a key role in atherothrombosis due to their ability of thrombus formation after rupture of an atherosclerotic plaque. Numerous clinical trials have established the efficacy of PLT function blockade in the prevention of acu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae990d8b348f4633f5e1ac40cdfb0e0
https://doi.org/10.1097/fjc.0b013e318279b78a
https://doi.org/10.1097/fjc.0b013e318279b78a
Autor:
Susanne M. Picker
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 11:49-57
Blood platelets play a key role in normal hemostasis but also in atherothrombosis due to their ability of thrombus formation at site of a ruptured atherosclerotic plaque. Platelets are also involved in vascular inflammation due to interactions with e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90de2354196ad03ece9094b80eaf41b2
https://doi.org/10.2174/1871525711311010009
https://doi.org/10.2174/1871525711311010009
Publikováno v:
Transfusion. 52:510-516
BACKGROUND: Previously, we evaluated the Mirasol pathogen reduction technology (PRT) system on platelet (PLT) function before resuspension. We now evaluated this system in the presence of PLT additive solution (PAS). STUDY DESIGN AND METHODS: Double-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75127e7d2fa0bb2c1af6811e53d3066d
https://doi.org/10.1111/j.1537-2995.2011.03323.x
https://doi.org/10.1111/j.1537-2995.2011.03323.x
Publikováno v:
ISBT Science Series. 5:114-119
Background Pathogen reduction technology (PRT) has been proven to reduce the residual risk of transmission of infectious agents. Reduction of various contaminating bacteriae, viruses and parasites by few to several log steps and efficiency to prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a23d098814c36072db2b48e83676db
https://doi.org/10.1111/j.1751-2824.2010.01417.x
https://doi.org/10.1111/j.1751-2824.2010.01417.x
Publikováno v:
Vox Sanguinis. 97:26-33
Background To examine if different pathogen-reduction technologies (PRTs) induce different degrees of platelet (PLT) storage lesion. Design Twenty-seven split triple-dose apheresis PLTs were PRT treated using ultraviolet light with either riboflavin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4765b039b3d969a571901596f50212c
https://doi.org/10.1111/j.1423-0410.2009.01176.x
https://doi.org/10.1111/j.1423-0410.2009.01176.x
Publikováno v:
Transfusion. 49:1224-1232
BACKGROUND: Pathogen inactivation/reduction technology (PRT) may alter quality of stored platelet (PLT) concentrates (PCs). Therefore, PLT adhesion and aggregation should be studied before transfusion of PRT-treated PLTs. STUDY DESIGN AND METHODS: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034ef87ed88ae7cccd05089ddf01ba82
https://doi.org/10.1111/j.1537-2995.2009.02092.x
https://doi.org/10.1111/j.1537-2995.2009.02092.x
Publikováno v:
Transfusion and Apheresis Science. 40:79-85
Background Mirasol pathogen reduction technology (PRT) treatment uses riboflavin (vitamin B 2 ) in combination with ultraviolet light (UV) to inactivate pathogens in platelet concentrates (PCs). This treatment has been reported to increase glycolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044b70dd430a69943ce7867656426e88
https://doi.org/10.1016/j.transci.2009.01.013
https://doi.org/10.1016/j.transci.2009.01.013
Autor:
Birgit S. Gathof, Susanne M. Picker, Paul M. Schneider, Arnulf H. Hoelscher, Daniel Vallböhmer, Elfriede Bollschweiler, Frederike C. Ling, Daniel R. Schmidt
Publikováno v:
Journal of Gastrointestinal Surgery. 13:581-586
Perioperative transfusion of allogeneic blood has been hypothesized to have an immunomodulatory effect and influence survival in several cancer types. This study evaluates the association between receipt of leucocyte-depleted and non-depleted allogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00d00fda79e11ee77638da5f5dabf9f
https://doi.org/10.1007/s11605-008-0787-1
https://doi.org/10.1007/s11605-008-0787-1
Publikováno v:
Transfusion Medicine and Hemotherapy. 36:114-120
BACKGROUND: Soluble mediators in platelet concentrates (PCs) released from contaminating white blood cells (WBCs) and platelets (PLTs) themselves are supposed to promote allergic and non-hemolytic febrile transfusion reactions in the recipient. Patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46763ea2841c5b71b533a9e2a34a28d
https://doi.org/10.1159/000203359
https://doi.org/10.1159/000203359
Publikováno v:
Transfusion. 48:1685-1692
Background The aim of this study was to examine the effects of a new riboflavin-based pathogen reduction technology (PRT), the Mirasol PRT process (Navigant Biotechnologies) on platelet (PLT) storage lesion development. Study design and methods A thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524d054c3188e289bcbb27c364afb340
https://doi.org/10.1111/j.1537-2995.2008.01778.x
https://doi.org/10.1111/j.1537-2995.2008.01778.x