Výsledky vyhledávání - "Susanne Kaufer"

Development of Safe and Highly Protective Live-Attenuated SARS-CoV-2 Vaccine Candidates by Genome Recoding

Autor: Julia Adler, Thomas Höfler, Volker Thiel, Luca D. Bertzbach, Joerg Jores, Azza Abdelgawad, Kristina Dietert, Andelé M. Conradie, Nadine Ebert, Fabien Labroussaa, Daria Vladimirova, Susanne Kaufer, Dusan Kunec, Achim D. Gruber, Tran Thi Nhu Thao, Jakob Trimpert, Nikolaus Osterrieder

Publikováno v: SSRN Electronic Journal.

Safe and effective vaccines are urgently needed to stop the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We constructed a series of live attenuated vaccine candidates by large-scale recoding of the SARS-CoV-2 genom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::829f0490112cea1aea88d650aec06abc
https://doi.org/10.2139/ssrn.3783405

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Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding

Autor: Volker Thiel, Tran Thi Nhu Thao, Julia Adler, Theresa C. Firsching, Jakob Trimpert, Nikolaus Osterrieder, Joerg Jores, Fabien Labroussaa, Susanne Kaufer, Dusan Kunec, Thomas Höfler, Achim D. Gruber, Azza Abdelgawad, Kristina Dietert, Nadine Ebert, Daria Vladimirova, Luca D. Bertzbach, Andelé M. Conradie

Publikováno v: Cell Reports
Trimpert, Jakob; Dietert, Kristina; Firsching, Theresa C; Ebert, Nadine; Tran, Thi Nhu Thao; Vladimirova, Daria; Kaufer, Susanne; Labroussaa, Fabien; Abdelgawad, Azza; Conradie, Andelé; Höfler, Thomas; Adler, Julia M; Bertzbach, Luca D; Jores, Jörg; Gruber, Achim D; Thiel, Volker; Osterrieder, Nikolaus; Kunec, Dusan (2021). Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding. Cell reports, 36(5), p. 109493. Cell Press 10.1016/j.celrep.2021.109493

Safe and effective vaccines are urgently needed to stop the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We construct a series of live attenuated vaccine candidates by large-scale recoding of the SARS-CoV-2 genome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b41ad2a1d3cb7ccdca98766f39f79ba

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The complex co-translational processing of glycoprotein GP5 of type 1 porcine reproductive and respiratory syndrome virus

Autor: Susanne Kaufer, Bastian Thaa, Bernadett Peibst, Eberhard Krause, Hans Nauwynck, Sara A. Neumann, Michael Veit

Publikováno v: Virus research. 240

GP5 and M, the major membrane proteins of porcine reproductive and respiratory syndrome virus (PRRSV), are the driving force for virus budding and a target for antibodies. We studied co-translational processing of GP5 from an European PRRSV-1 strain.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640992bd424244e6f29b7423ec2c41d9
https://pubmed.ncbi.nlm.nih.gov/28807563

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The Cellular Chaperone Hsc70 Is Specifically Recruited to Reovirus Viral Factories Independently of Its Chaperone Function

Autor: Susanne Kaufer, John S. L. Parker, Caroline M. Coffey

Publikováno v: Journal of Virology. 86:1079-1089

Mammalian orthoreoviruses replicate and assemble in the cytosol of infected cells. A viral nonstructural protein, μNS, forms large inclusion-like structures called viral factories (VFs) in which assembling viral particles can be identified. Here we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0061271862e9090391d0cb6730eea41
https://doi.org/10.1128/jvi.02662-10

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Multiple host proteins that function in phosphatidylinositol-4-phosphate metabolism are recruited to the chlamydial inclusion

Autor: Marci A. Scidmore, Joo-Yong Jung, Andrew M. Moorhead, Susanne Kaufer, Asya Smirnov

Publikováno v: Infection and immunity. 78(5)

Chlamydiae replicate within a nonacidified vacuole, termed an inclusion. As obligate intracellular bacteria, chlamydiae actively modify their vacuole to exploit host signaling and trafficking pathways. Recently, we demonstrated that several Rab GTPas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467ba5d201d667b75e2106d94bedeb30
https://pubmed.ncbi.nlm.nih.gov/20231409

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