Platelet aggregation during targeted temperature management after out-of-hospital cardiac arrest: A randomised clinical trial

Autor: Anni Nørgaard Jeppesen, Anne-Mette Hvas, Anders Morten Grejs, Christophe Duez, Susanne Ilkjær, Hans Kirkegaard

Publikováno v: Platelets, Vol 29, Iss 5, Pp 504-511 (2018)

Some studies conclude that mild hypothermia causes platelet dysfunction leading to an increased bleeding risk, whereas others state that platelet aggregation is enhanced during mild hypothermia. Therefore, the aim of this study was to clarify whether

Externí odkaz: https://doaj.org/article/118a523fd79342d3bc4599d68190edd0

Prolonged targeted temperature management compromises thrombin generation:A randomised clinical trial

Autor: Anders Morten Grejs, Susanne Ilkjær, Anne-Mette Hvas, Christophe Henri Valdemar Duez, Anni Nørgaard Jeppesen, Hans Kirkegaard

Publikováno v: Jeppesen, A N, Hvas, A-M, Duez, C H V, Grejs, A M, Ilkjær, S & Kirkegaard, H 2017, ' Prolonged targeted temperature management compromises thrombin generation : A randomised clinical trial ', Resuscitation, vol. 118 . https://doi.org/10.1016/j.resuscitation.2017.06.004

AIM: To investigate whether prolonged compared with standard duration of targeted temperature management (TTM) compromises coagulation.METHODS: Comatose survivors after out-of-hospital cardiac arrest (n=82) were randomised to standard (24h) or prolon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3257453d11e5354d069183f3812157e9
https://pure.au.dk/portal/da/publications/prolonged-targeted-temperature-management-compromises-thrombin-generation(c5c50c15-2290-4e68-ad6a-db95c49b2178).html

A statistical analysis protocol for the time-differentiated target temperature management after out-of-hospital cardiac arrest (TTH48) clinical trial

Autor: Timo Laitio, Anders Morten Grejs, Susanne Ilkjær, Markus B. Skrifvars, Fabio Silvio Taccone, Valdo Toome, Inge de Haas, Christophe Henri Valdemar Duez, Jakob Hjort, Anni Nørgaard Jeppesen, Anne Kaltoft, Asger Roer Pedersen, Jørgen Feldbæk Nielsen, Bodil Steen Rasmussen, Ville Pettilä, Christian Storm, Urmet Arus, Alf Inge Larsen, Eldar Søreide, Hans Kirkegaard

Publikováno v: Kirkegaard, H, Pedersen, A R, Pettilä, V, Hjort, J, Rasmussen, B S, de Haas, I, Nielsen, J F, Ilkjær, S, Kaltoft, A, Jeppesen, A N, Grejs, A M, Duez, C H V, Larsen, A I, Toome, V, Arus, U, Taccone, F S, Storm, C, Laitio, T, Skrifvars, M B & Søreide, E 2016, ' A statistical analysis protocol for the time-differentiated target temperature management after out-of-hospital cardiac arrest (TTH48) clinical trial ', Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, vol. 24, no. 1, pp. 138 . https://doi.org/10.1186/s13049-016-0334-0
Kirkegaard, Hans; Pedersen, Asger Roer; Pettilä, Ville Yrjö Olavi; Hjort, Jakob; Rasmussen, Bodil Steen; de Haas, Inge; Nielsen, Jørgen Feldbæk; Ilkjær, Susanne; Kaltoft, Anne; Jeppesen, Anni Nørgaard; Grejs, Anders Morten; Duez, Christophe Henri Valdemar; Larsen, Alf Inge; Toome, Valdo; Arus, Urmet; Taccone, Fabio Silvio; Storm, Christian; Laitio, Timo; Skrifvars, Markus B and Søreide, Eldar (2016). A statistical analysis protocol for the time-differentiated target temperature management after out-of-hospital cardiac arrest (TTH48) clinical trial. Scandinavian journal of trauma, resuscitation and emergency medicine, 24(1), p. 138. BioMed Central 10.1186/s13049-016-0334-0
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 24 (1
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Background: The TTH48 trial aims to determine whether prolonged duration (48 hours) of targeted temperature management (TTM) at 33 (±1) °C results in better neurological outcomes compared to standard duration (24 hours) after six months in comatose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024b41c31751f38964347eff3a567003
http://hdl.handle.net/10138/173797

Influence of temperature on thromboelastometry and platelet aggregation in cardiac arrest patients undergoing targeted temperature management

Autor: Anne-Mette Hvas, Anni Nørgaard Jeppesen, Hans Kirkegaard, Susanne Ilkjær

Publikováno v: Jeppesen, A N, Kirkegaard, H, Ilkjær, S & Hvas, A M 2016, ' Influence of temperature on thromboelastometry and platelet aggregation in cardiac arrest patients undergoing targeted temperature management ', Critical Care (Online Edition), vol. 20, no. 1, pp. 118 . https://doi.org/10.1186/s13054-016-1302-9
Critical Care

BACKGROUND: Coagulation can be visualised using whole blood coagulation analyses such as thromboelastometry and platelet aggregation tests; however, the role of temperature in the analyses is ambiguous. The aim was to examine whether temperature infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599509f1dd1f8b50063ee1312318203a
https://pure.au.dk/portal/da/publications/influence-of-temperature-on-thromboelastometry-and-platelet-aggregation-in-cardiac-arrest-patients-undergoing-targeted-temperature-management(c372fb22-013d-497c-a127-fc03787af44a).html

Relationship between mechanical sensitivity and postamputation pain: a prospective study

Autor: Susanne Ilkjær, Troels S. Jensen, Lone Nikolajsen

Publikováno v: Aarhus University
Nikolajsen, L, IlKjær, S & Jensen, T S 2000, ' Relationship between mechanical sensitivity and postamputation pain: A prospective study ', Eur. J. Pain., vol. 4, pp. 327-334 .

Limb amputation is followed by stump and phantom pain in a large proportion of amputees and postamputation pain may be associated with signs of hyperexcitability such as hyperalgesia to mechanical stimulation. The present study examined the possible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e917dacc0f1290ed6f2f18028c48eff
https://doi.org/10.1053/eujp.2000.0194