Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Susanne I. Fuchs"'
Publikováno v:
Journal of Cystic Fibrosis. 15:123-126
To assess whether long-term inhalation with hypertonic saline is able to halt the progression of mild CF lung disease, we analysed longitudinal data of lung clearance index (LCI) and spirometry. A total of 34 patients with mild lung disease (FEV1 ≥
Publikováno v:
Respiratory Medicine, 108(9), 1254-1259. W B SAUNDERS CO LTD
INTRODUCTION: Children with asthma often have normal spirometry despite significant disease. The pathology of the small airways in asthma may be assessed using Multiple Breath Washout (MBW) and calculating the Lung Clearance Index (LCI). There are on
Autor:
Susanne I. Fuchs, Helmut Ellemunter, J. Eder, Gratiana Steinkamp, Karin M. Unsinn, Monika Gappa
Publikováno v:
Respiratory Medicine. 108:865-874
Summary Introduction Lung disease remains the main cause of morbidity and mortality in patients with Cystic Fibrosis (CF). To detect lung disease before clinical symptoms become apparent, sensitive tools are essential. Spirometry is used for monitori
Publikováno v:
Journal of Cystic Fibrosis. 12:277-283
BackgroundVolumetric capnography reflecting the course of CO2-exhalation is used to assess ventilation inhomogeneity. Calculation of the slope of expiratory phase 3 and the capnographic index (KPIv) from expirograms allows quantification of extent an
Autor:
Frank Ahrens, Nicolaus Schwerk, Matthias Griese, Winfried Baden, Doris Staab, Susanne I. Fuchs, Wolfgang Gleiber, Thomas Köhnlein, Monika Gappa, Klaus Pittschieler, Ernst Rietschel, Robert Bals
Publikováno v:
5.2 Monitoring Airway Disease.
We have shown that the Lung Clearance Index (LCI) derived from Multiple Breath Nitrogen Washout (MBW N2 ) is more sensitive for detecting pulmonary changes than spirometry, with an abnormal LCI in almost 40% of patients with a normal FEV 1 . The aim
Autor:
Matthias Griese, Susanne I. Fuchs, Jan Ripper, J. Eder, Helmut Ellemunter, Susanne Zeidler, Uwe Mellies, Frank Ahrens, Burkhard Tümmler, Doris Staab, Andrea Jobst, Ernst Rietschel, Jörg Grosse-Onnebrink, Monika Gappa
Publikováno v:
Pediatric Pulmonology. 47:649-657
The Lung Clearance Index (LCI) is superior to spirometry in detecting early lung disease in cystic fibrosis (CF) and correlates with structural lung changes seen on CT scans. The LCI has the potential to become a novel outcome parameter for clinical
Autor:
Monika Gappa, Susanne I. Fuchs
Publikováno v:
Paediatric Respiratory Reviews. 12:264-270
Multiple breath washout (MBW) has been demonstrated to be sensitive for assessing ventilation inhomogeneity (VI). VI is supposed to reflect changes in peripheral airways which are not apparent using spirometry. The lung clearance index (LCI) is the m
Publikováno v:
Pediatric Pulmonology. 45:301-306
Multiple breath washout (MBW) for measuring the lung clearance index (LCI) has been proposed as a non-invasive tool for detecting early cystic fibrosis (CF) lung disease. The LCI is highly repeatable and reproducible in healthy subjects. In patients
Publikováno v:
Pediatric Pulmonology. 44:1180-1185
There is increasing interest in using the Multiple Breath Washout technique and the lung clearance index (LCI) for detecting early pulmonary changes, for example, in cystic fibrosis lung disease. However, there are still limited data regarding equipm
Autor:
Ernst Rietschel, Nicolaus Schwerk, Matthias Griese, Winfried Baden, Georg Hülskamp, Robert Bals, Klaus Pittschieler, Thomas Köhnlein, Ludmilla Reckling, Susanne I. Fuchs, Sebastian Fähndrich, Wolfgang Gleiber, Frank Ahrens, Monika Gappa, Doris Staab
Publikováno v:
Respiratory medicine. 116
Patients with alpha-1-antitrypsin deficiency (AATD) and a PI-ZZ genotype are at high risk to develop severe emphysema during adulthood. However, little is known about early stages of emphysema and disease manifestation in other PI-types. Spirometry i