Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Susanne Hirschel-Scholz"'
Publikováno v:
Journal of the American Academy of Dermatology. 25:437-442
A woman had symmetrically distributed pruritic nodules for more than 40 years. Microscopically they were characterized by proliferation of nonmyelinated nerve fibers (Pautrier's neuroma) and a total absence of epidermal involvement. Anetoderma develo
Publikováno v:
Pediatric Dermatology. 7:323-323
Publikováno v:
British Journal of Dermatology. 120:639-644
Isotretinoin differs from acitretin and Ro137410 by its striking sebostatic effect in acne after oral, but not topical, administration. The reason for this is not yet understood. Previous studies indicate that cellular retinoic acid binding protein (
Publikováno v:
Dermatology. 175:13-19
Human skin contains several proteins that could bind retinoids. One is the retinol-binding protein (RBP, the plasma carrier of natural vitamin A, retinol, which was found to also bind retinoic acid (RA) in vitro. A polyacrylamide gel electrophoresis
Publikováno v:
Calcified Tissue International. 40:103-108
Pharmacological inhibition of parathyroid hormone (PTH) secretion has been the object of several experimental and clinical trials in the past. It is only recently that a drug, WR-2721 [S-,2-(3-aminopropylamino)-,ethylphosphorothioic acid], has been s
Publikováno v:
Dermatology. 176:191-199
Ro 13-7410 was given to 29 patients (a total of 38 treatment courses) for 7.5 weeks (range 4–23). This compound is one of the most potent retinoids ever synthetized and has the highest affinity to human skin cellular retinoic-acid-binding protein.
Publikováno v:
European journal of clinical investigation. 19(2)
Retinoic acid (RA) is bound intracellularly by a specific, low molecular weight protein (CRABP), that is unrelated to its nuclear receptor and whose function and regulation are still unknown. In the present study we were able to obtain an in vivo mod