Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Susanne Herwig"'
Autor:
Susanne Herwig, Julia M. Adler, Daria Vladimirova, Jakob Trimpert, Jalid Sehouli, Günter Cichon
Publikováno v:
Vaccines, Vol 12, Iss 3, p 248 (2024)
During the COVID-19 pandemic, the early emergence of viral variants repeatedly undermined the effects of vaccination. Our aim here is to explore strategies for improving spike vaccine gene antigenicity by merging mutations from different variants of
Externí odkaz:
https://doaj.org/article/3cd5b0c233ae4bbb92fbbcc8550a71b6
Autor:
Jakob Trimpert, Susanne Herwig, Julia Stein, Daria Vladimirova, Julia M. Adler, Azza Abdelgawad, Theresa C. Firsching, Tizia Thoma, Jalid Sehouli, Klaus Osterrieder, Achim D. Gruber, Birgit Sawitzki, Leif Erik Sander, Günter Cichon
Publikováno v:
Viruses, Vol 13, Iss 11, p 2290 (2021)
With the exception of inactivated vaccines, all SARS-CoV-2 vaccines currently used for clinical application focus on the spike envelope glycoprotein as a virus-specific antigen. Compared to other SARS-CoV-2 genes, mutations in the spike protein gene
Externí odkaz:
https://doaj.org/article/b30d56503a0141bb824f2651c751f2d7
Autor:
Geraldine Nouailles, Julia M. Adler, Peter Pennitz, Stefan Peidli, Gustavo Teixeira Alves, Morris Baumgart, Judith Bushe, Anne Voss, Alina Langenhagen, Fabian Pott, Julia Kazmierski, Cengiz Goekeri, Szandor Simmons, Na Xing, Christine Langner, Ricardo Martin Vidal, Azza Abdelgawad, Susanne Herwig, Günter Cichon, Daniela Niemeyer, Christian Drosten, Christine Goffinet, Markus Landthaler, Nils Blüthgen, Haibo Wu, Martin Witzenrath, Achim D. Gruber, Samantha D. Praktiknjo, Nikolaus Osterrieder, Emanuel Wyler, Dusan Kunec, Jakob Trimpert
Vaccines are a cornerstone in COVID-19 pandemic management. Here, we compare immune responses to and preclinical efficacy of the mRNA vaccine BNT162b2, an adenovirus-vectored spike vaccine, and the live-attenuated-virus vaccine candidate sCPD9 after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98b0dc6876e31b59e9b8dcc55a0c9db8
https://doi.org/10.1101/2022.05.16.492138
https://doi.org/10.1101/2022.05.16.492138
Autor:
Jalid Sehouli, Susanne Herwig, Jakob Trimpert, Achim D. Gruber, Tizia Thoma, Leif E. Sander, Julia Adler, Günter Cichon, Julia Stein, Birgit Sawitzki, Daria Vladimirova, Theresa C. Firsching, Azza Abdelgawad, Klaus Osterrieder
Publikováno v:
Viruses
Volume 13
Issue 11
Viruses, Vol 13, Iss 2290, p 2290 (2021)
Volume 13
Issue 11
Viruses, Vol 13, Iss 2290, p 2290 (2021)
With the exception of inactivated vaccines, all SARS-CoV-2 vaccines currently used for clinical application focus on the spike envelope glycoprotein as a virus-specific antigen. Compared to other SARS-CoV-2 genes, mutations in the spike protein gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc87464007ffda2f2ecfa7986bc7ffb7
https://doi.org/10.17169/refubium-33486
https://doi.org/10.17169/refubium-33486
Publikováno v:
Herz. 26:55-63
Die Behandlung von Patienten mit ventrikularen Tachyarrhythmien und gleichzeitigen atrialen Tachyarrhythmien stellt grose Anforderungen an die modernen implantierbaren Defibrillatoren. Supraventrikulare Tachyarrhythmien wie Vorhofflimmern, Vorhofflat
Autor:
Susanne Herwig, Berndt Lüderitz, Heyder Omran, B. Esmailzadeh, Christian Wolpert, Werner Jung, Christian Vahlhaus, Burghard Schumacher, Thorsten Lewalter, Rainer Schimpf, Susanne Spehl, Arnim Welz
Publikováno v:
Journal of Interventional Cardiac Electrophysiology. 4:185-195
The high prevalence of atrial fibrillation (AF) and its clinical complications, the poor efficacy of medical therapy for preventing recurrences, and dissatisfaction with alternative modes of therapy stimulated interest in implantable atrial and combi
Autor:
Michael Strauss, Susanne Herwig
Publikováno v:
European Journal of Biochemistry. 246:581-601
The retinoblastoma susceptibility gene is a tumour suppressor and its product retinoblastoma protein (pRb) has been known for 10 years as a repressor of progression towards S phase. Its major activity was supposed to be sequestration or inactivation
Publikováno v:
Blood. 87:350-364
Defensins are microbicidal peptides and the principal constituents of neutrophil primary granules. They are presumed to play a prominent role in innate host defenses. We examined defensin mRNA levels during drug-induced differentiation of the promyel
Autor:
Thomas E. Willnow, Dagmara Niedzielska, Peter M. Schlag, Susanne Herwig, Peter Löser, Joerg Heeren, G Cichon, Frank Schnieders, Hartmut H.-J. Schmidt, Tahar Benhidjeb, Wolfgang Uckert
Publikováno v:
The journal of gene medicine. 6(2)
Background Gene therapy of familial hypercholesterolemia (FH) requires successful transfer and lifelong expression of a functional low density lipoprotein receptor (LDLr) gene in the liver. Most of the vector systems currently employed for gene thera
Publikováno v:
Leukemia research. 22(10)
Defensin transcription in HL-60 promyelocytic leukemia cells is greatly enhanced during retinoic acid (RA)-induced differentiation. We have probed this regulatory pathway by selective modulation of various kinase activities. Induction was potentiated