Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Susanne Häußler"'
Autor:
Larissa Dirr, Sven Cleeves, Isabel Ramón Roth, Linghui Li, Timm Fiebig, Thomas Ve, Susanne Häussler, Armin Braun, Mark von Itzstein, Jana I. Führing
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTMultidrug-resistant bacteria such as the opportunistic pathogen Pseudomonas aeruginosa, which causes life-threatening infections especially in immunocompromised individuals and cystic fibrosis patients, pose an increasing threat to public hea
Externí odkaz:
https://doaj.org/article/d8d00c4b95764f78a4b8670e9a0d7496
Autor:
Sebastian Roman Borgert, Steffi Henke, Florian Witzgall, Stefan Schmelz, Susanne zur Lage, Sven-Kevin Hotop, Steffi Stephen, Dennis Lübken, Jonas Krüger, Nicolas Oswaldo Gomez, Marco van Ham, Lothar Jänsch, Markus Kalesse, Andreas Pich, Mark Brönstrup, Susanne Häussler, Wulf Blankenfeldt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Pseudomonas aeruginosa is a major cause of nosocomial infections and also leads to severe exacerbations in cystic fibrosis or chronic obstructive pulmonary disease. Three intertwined quorum sensing systems control virulence of P. aeruginosa,
Externí odkaz:
https://doaj.org/article/0f0b91a8c4f34e998f22e33116f8f4b6
Autor:
Gang Wang, Jean-Michel Brunel, Matthias Preusse, Negar Mozaheb, Sven D. Willger, Gerald Larrouy-Maumus, Pieter Baatsen, Susanne Häussler, Jean-Michel Bolla, Françoise Van Bambeke
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
The polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics through permeabilizing the outer membrane and increases the activity of antibiotics on biofilms.
Externí odkaz:
https://doaj.org/article/33f1fe5183d344fa843566795f556d80
Autor:
Kathrin Alpers, Elisabeth Vatareck, Lothar Gröbe, Mathias Müsken, Maren Scharfe, Susanne Häussler, Jürgen Tomasch
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT Bacteria either duplicate their chromosome once per cell division or a new round of replication is initiated before the cells divide, thus cell cycles overlap. Here, we show that the opportunistic pathogen Pseudomonas aeruginosa switches fro
Externí odkaz:
https://doaj.org/article/6d451498c0cd4d009f2bd1c5ec6682ea
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 4, Pp 3648-3669 (2022)
ABSTRACT: The involvement of adipose tissue (AT) in metabolism is not limited to energy storage but turned out to be much more complex. We now know that in addition to lipid metabolism, AT is important in glucose homeostasis and AA metabolism and als
Externí odkaz:
https://doaj.org/article/b93b27ffb69741b2a46814a8f97dec98
Autor:
Michal Koska, Adrian Kordes, Jelena Erdmann, Sven D. Willger, Janne G. Thöming, Heike Bähre, Susanne Häussler
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Heterogeneous environments such as the chronically infected cystic fibrosis lung drive the diversification of Pseudomonas aeruginosa populations into, e.g., mucoid, alginate-overproducing isolates or small-colony variants (SCVs). In this stu
Externí odkaz:
https://doaj.org/article/4ea71df8fbc64c68836cd56d40234866
Autor:
Alexander Jeske, Alejandro Arce-Rodriguez, Janne G. Thöming, Jürgen Tomasch, Susanne Häussler
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-14 (2022)
Abstract The overall success of a pathogenic microbe depends on its ability to efficiently adapt to challenging conditions in the human host. Long-term evolution experiments track and predict adaptive trajectories and have contributed significantly t
Externí odkaz:
https://doaj.org/article/7194727173c6435a902e700f29ca2c6c
Autor:
Alejandro Arce-Rodríguez, Debbie Pankratz, Matthias Preusse, Pablo I. Nikel, Susanne Häussler
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT In light of the antibiotic crisis, emerging strategies to sensitize bacteria to available antibiotics should be explored. Several studies on the mechanisms of killing suggest that bactericidal antibiotic activity is enforced through the gene
Externí odkaz:
https://doaj.org/article/99f0b3dad93c46ce831e5b46c0ddbd8c
Autor:
Janne G. Thöming, Susanne Häussler
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Biofilm-associated bacteria exhibit profound changes in bacterial physiology. They thrive in the environment but also in the human host in protected sessile communities. Antimicrobial therapy usually fails, despite the absence of genotypic resistance
Externí odkaz:
https://doaj.org/article/efb45c7a66e24f68abee5044b7e4ca0f
Publikováno v:
mSystems, Vol 6, Iss 4 (2021)
ABSTRACT The design of novel antibiotics relies on a profound understanding of their mechanism of action. While it has been shown that cellular effects of antibiotics cluster according to their molecular targets, we investigated whether compounds bin
Externí odkaz:
https://doaj.org/article/e708be2126b94522ba7b743449dfa498