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of 20
pro vyhledávání: '"Susanne Ganepola"'
Autor:
Gero Hütter, Susanne Ganepola
Publikováno v:
The Scientific World Journal, Vol 11, Pp 1068-1076 (2011)
Today, 30 years after the onset of the HIV pandemic, although treatment strategies have considerably improved, there is still no cure for the disease. Recently, we described a successful hematopoietic stem cell transplantation in an HIV-1–infected
Externí odkaz:
https://doaj.org/article/defc5a6f122d4066860a0d8c9e42b0d7
Autor:
Gero Hütter, Susanne Ganepola
Publikováno v:
Experimental Biology and Medicine. 236:938-943
Humans respond differently toward exposure against pathogens and some individuals are completely resistant against transmission due to a genetically determined susceptibility. A rising number of such, so-called, host factors have been described durin
Autor:
Susanne Ganepola, Gero Hütter
Publikováno v:
The Scientific World Journal
The Scientific World Journal, Vol 11, Pp 1068-1076 (2011)
The Scientific World Journal, Vol 11, Pp 1068-1076 (2011)
Today, 30 years after the onset of the HIV pandemic, although treatment strategies have considerably improved, there is still no cure for the disease. Recently, we described a successful hematopoietic stem cell transplantation in an HIV-1–infected
Autor:
Susanne Ganepola, I. W. Blau, Andrea Stroux, Petra Reinke, S. Schwarck, Eckhard Thiel, Lutz Uharek, Martin Schmidt-Hieber
Publikováno v:
International Journal of Hematology. 91:877-885
We analyzed cytomegalovirus (CMV) infection risk factors and immune reconstitution kinetics in 89 patients after allogeneic stem cell transplantation (allo-SCT). The use of alemtuzumab for in vivo T cell depletion (TCD) had, besides the donor/recipie
Publikováno v:
Journal of Infection Prevention. 10:198-203
Invasive pulmonary aspergillosis (IPA) represents ~ a major cause of morbidity and mortality in patients I with impaired function of the immune system such as in patients with acute myeloid leukaemia (AML). We investigated the in uence of the patient
Autor:
Gero Hütter, Daniel Nowak, Maximilian Mossner, Susanne Ganepola, Arne Müßig, Kristina Allers, Thomas Schneider, Jörg Hofmann, Claudia Kücherer, Olga Blau, Igor W. Blau, Wolf K. Hofmann, Eckhard Thiel
Publikováno v:
New England Journal of Medicine. 360:692-698
Infection with the human immunodeficiency virus type 1 (HIV-1) requires the presence of a CD4 receptor and a chemokine receptor, principally chemokine receptor 5 (CCR5). Homozygosity for a 32-bp deletion in the CCR5 allele provides resistance against
Autor:
Susanne Ganepola, Lutz Uharek, Eckhard Thiel, S. Schwarck, Martin Schmidt-Hieber, Andrea Stroux, I. W. Blau
Publikováno v:
Bone Marrow Transplantation. 44:185-192
We developed a novel algorithm to define the need for high-dose prophylactic i.v. Igs (IVIG) in periods of high risk for CMV to patients after allo-SCT. IVIG were administered only if at least one of the following, monthly-assessed, criteria was fulf
Publikováno v:
Bioscience Hypotheses. 1:213-217
Over a long period of time, the impact of inhibiting angiogenesis as an option to treat malignancies, has been uncertain. Since the introduction of bevacizumab in the therapy of colorectal cancer, the mechanism and understanding of angiogenesis have
Autor:
Chiara Gentilini, Lutz Uharek, Wolfgang Herr, Arne Muessig, Andrea Stroux, Susanne Ganepola, Olaf Penack, Ralf G. Meyer, Lars Fischer, A Nogai, Eckhard Thiel, K Rieger
Publikováno v:
Bone Marrow Transplantation. 41:377-383
Although thymoglobulin and alemtuzumab are frequently used in hematopoietic stem cell transplantation (HSCT), little is known of their effects on NK cells, which mediate important functions in post-transplantation immunology. In the present study, we
Autor:
Lars Fischer, Axel Nogai, Olaf Penack, Olga Marinets, Susanne Ganepola, Constanze Kliem, Andrea Stroux, Igor Wolfgang Blau, Lutz Uharek, Arne Muessig, Chiara Gentilini, Eckhard Thiel, Thoralf Lange
Publikováno v:
International Journal of Hematology. 85:326-332
The antitumor activity of natural killer (NK) cells has recently been shown to be assessable at a single-cell level via flow cytometric detection of CD107a. We used this novel method to prospectively quantify and characterize tumor-reactive NK cells