Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Susanne E. Hede"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 303:C151-C159
Potassium channels play a vital role in maintaining the membrane potential and the driving force for anion secretion in epithelia. In pancreatic ducts, which secrete bicarbonate-rich fluid, the identity of K+ channels has not been extensively investi
Autor:
Lene Juul Pedersen, Dan A. Klaerke, Boy Høyer, Pernille Bøttger, Susanne E. Hede, Morten Grunnet
Publikováno v:
American Journal of Physiology-Cell Physiology. 291:C1377-C1387
The general phosphate need in mammalian cells is accommodated by members of the Pitransport (PiT) family ( SLC20), which use either Na+or H+to mediate inorganic phosphate (Pi) symport. The mammalian PiT paralogs PiT1 and PiT2 are Na+-dependent Pi(NaP
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 450:429-436
Extracellular ATP is an important regulator of transepithelial transport in a number of tissues. In pancreatic ducts, we have shown that ATP modulates epithelial K+ channels via purinergic receptors, most likely the P2Y2 and P2Y4 receptors, but the i
Publikováno v:
Drug Development Research. 59:128-135
ATP and other nucleotides are released from various cells, but the pathway and physiological stimulus for ATP release are often unclear. The focus of our studies is the understanding of ATP release and signaling in rat exocrine pancreas. In acinar su
Publikováno v:
Journal of Biological Chemistry. 274:31784-31791
In epithelia, extracellular nucleotides are often associated with regulation of ion transporters, especially Cl− channels. In this study, we investigated which purinoceptors are present in native pancreatic ducts and how they regulate ion transport
Autor:
Ivana Novak, Simon Krabbe, Jing Wang, Susanne E. Hede, Kristian Agmund Haanes, Roland Nitschke, Katrine L. Henriksen
Pancreas secretes fluid rich in digestive enzymes and bicarbonate. The alkaline secretion is important in buffering of acid chyme entering duodenum and for activation of enzymes. This secretion is formed in pancreatic ducts, and studies to date show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c63565881e368fb46e1a43af9d09d2d
https://europepmc.org/articles/PMC3012985/
https://europepmc.org/articles/PMC3012985/
Publikováno v:
Pflugers Archiv : European journal of physiology. 456(2)
Previously, we have shown that pancreatic acini release adenosine triphosphate (ATP) and ATP-handling enzymes, and pancreatic ducts express various purinergic P2 receptors. The aim of the present study was to establish whether pancreatic ducts also e
Publikováno v:
The FASEB Journal. 21
Publikováno v:
The Journal of Medical Investigation. 56:355-356
recognized as important extracellular signaling molecules in many biological systems (1). In epithelia, ATP signaling is thought to regulate fluid transport, and exocrine glands are one of the first epithelia where the effect of ATP on ion channels a