Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Susanne Bredenberg"'
Publikováno v:
International Journal of Pharmaceutics. 488:102-107
With the increasing number of misuse and abuse of opioids, the resistance to tampering becomes an important attribute for transdermal opioid patches. In this study, drug-containing geopolymer granules were integrated into an adhesive matrix to improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f771041129646b392cdc08b4a411027
https://doi.org/10.1016/j.ijpharm.2015.04.061
https://doi.org/10.1016/j.ijpharm.2015.04.061
Publikováno v:
International Journal of Pharmaceutics. 465:169-174
Tamper-resistance is an important property of controlled-release formulations of opioid drugs. Tamper-resistant formulations aim to increase the degree of effort required to override the controlled release of the drug molecules from extended-release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bf2ef336197b622b96dc24ca6df3d1
https://doi.org/10.1016/j.ijpharm.2014.02.029
https://doi.org/10.1016/j.ijpharm.2014.02.029
Publikováno v:
Pain Research and Treatment, Vol 2012 (2012)
Pain Research and Treatment
Pain Research and Treatment
In vitro drug release tests are a widely used tool to measure the variance between transdermal product performances and required by many authorities. However, the result cannot provide a good estimation of the in vivo drug release. In the present wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef878d03341d75fc9288e6e608256be5
https://doi.org/10.1155/2012/953140
https://doi.org/10.1155/2012/953140
Publikováno v:
Journal of Pharmaceutical Sciences. 101:1803-1810
This study investigates the influence of drug solubility and distribution on its release from inert geopolymer pellets of three different sizes (1.5 × 1.5, 3 × 6, and 6 × 6 mm), having the same geopolymer composition and containing highly potent o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4682b935ffaddd73c8ed88630e5f1220
https://doi.org/10.1002/jps.23071
https://doi.org/10.1002/jps.23071
Publikováno v:
Results in Pharma Sciences. 2:23-28
Improving acid resistance, while maintaining the excellent mechanical stability is crucial in the development of a sustained and safe oral geopolymer dosage form for highly potent opioids. In the present work, commercially available Methacrylic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4850d236a2b822d11306535af1a54452
Publikováno v:
Journal of Controlled Release. 146:370-377
We propose that a clay derived class of materials, known as geopolymers, may solve the problem of finding materials for controlled release with the right combination of properties necessary for a safe and sustained oral delivery of highly potent opio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e0de98e0f85706822842c1c32918e9
https://doi.org/10.1016/j.jconrel.2010.05.029
https://doi.org/10.1016/j.jconrel.2010.05.029
Publikováno v:
Journal of Pharmaceutical Sciences. 99:219-226
Pellets composed of the ceramic material Halloysite and microcrystalline cellulose were synthesized with the aim of producing a drug delivery vehicle for sustained release of the opioid Fentanyl with low risk for dose dumping at oral intake of the hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b57ff599fa8f22b8c452bce25c617094
https://doi.org/10.1002/jps.21814
https://doi.org/10.1002/jps.21814
Publikováno v:
Pharmaceutical Research. 26:1618-1625
To create improved pharmaceutical formulations for nasal and sublingual administration of desmopressin and investigate their pharmacokinetic profiles in comparison with a commercial nasal liquid spray and finally to evaluate the volunteers' opinions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce6da4a4c6bfb1b234fa8e3d46e3cd3
https://doi.org/10.1007/s11095-009-9871-9
https://doi.org/10.1007/s11095-009-9871-9
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 94
To reduce the effort required to penetrate the skin and optimize drug release profiles, bioceramic microneedle arrays with higher-aspect-ratio needles and a flexible and self-swelling substrate have been developed. Swelling of the substrate can assis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77c36d8d484c81984d1afbdcc713e35
https://pubmed.ncbi.nlm.nih.gov/26126420
https://pubmed.ncbi.nlm.nih.gov/26126420
Autor:
Hans Lennernäs, M Holmberg, Bo Lennernäs, Christer Nyström, Thomas Hedner, Susanne Bredenberg
Publikováno v:
British Journal of Clinical Pharmacology. 59:249-253
It is estimated that two-thirds of cancer patients will at some point during their illness experience breakthrough pain. In this study, the pharmacokinetics of a novel sublingual dosage form of fentanyl developed for breakthrough pain was evaluated.E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a9e7246076d55155910ee7300dc30d
https://doi.org/10.1111/j.1365-2125.2004.02264.x
https://doi.org/10.1111/j.1365-2125.2004.02264.x