Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Susanne Beyer"'
Autor:
Mareike Mannewitz, Thomas Kolben, Carolin Perleberg, Sarah Meister, Laura Hahn, Sophie Mitter, Elisa Schmoeckel, Sven Mahner, Stefanie Corradini, Fabian Trillsch, Mirjana Kessler, Udo Jeschke, Susanne Beyer
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102116- (2024)
Objectives: The chemokine CCL22 is recognized for recruiting immunosuppressive regulatory T-cells (Treg) that contribute to disease progression in various tumor entities helping them to evade the host immune response. Our study aims to identify the e
Externí odkaz:
https://doaj.org/article/a1d7f82746124e98acf4d69eadacae70
Autor:
Christina Buschmann, Laura Unverdorben, Julia Knabl, Stefan Hutter, Sarah Meister, Susanne Beyer, Maximiliane Burgmann, Lucia Keilmann, Alaleh Zati zehni, Elisa Schmoeckel, Mirjana Kessler, Udo Jeschke, Sven Mahner, Thomas Kolben, Franziska Ganster, Alexander Burges
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8840-8851 (2023)
Galectins are known to play an important role in immunoregulatory processes and autoimmune diseases. Galectin-10 is a cytoplasmic protein of human eosinophils and is involved in various eosinophilic diseases. Since increased galectin expression is al
Externí odkaz:
https://doaj.org/article/f3b37256f3df4904be4d65b037dceb5c
Autor:
Susann Badmann, Doris Mayr, Elisa Schmoeckel, Anna Hester, Christina Buschmann, Susanne Beyer, Thomas Kolben, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In recurrent epithelial ovarian cancer (EOC) most patients develop platinum-resistance. On molecular level the NRF2 pathway, a cellular defense mechanism against reactive oxygen species, is induced. In this study, we investigate AKR1C1/2, ta
Externí odkaz:
https://doaj.org/article/51dfe0d42da94dd1b154d81478a61c37
Autor:
Marie Forster, Rachel Wuerstlein, Alexander Koenig, Niklas Amann, Susanne Beyer, Till Kaltofen, Tom Degenhardt, Alexander Burges, Fabian Trillsch, Sven Mahner, Nadia Harbeck, Anca Chelariu-Raicu
Publikováno v:
Breast, Vol 60, Iss , Pp 214-222 (2021)
Introduction: The side effects of systemic cancer therapy and the lack of clinical data on safety and efficacy of COVID-19 vaccination in cancer patients cause uncertainty among the patients about whether to get vaccinated or not. Here, we evaluated
Externí odkaz:
https://doaj.org/article/c56b223aaf9545459022a504855c2e26
Autor:
Lili Lin, Christina Kuhn, Nina Ditsch, Thomas Kolben, Bastian Czogalla, Susanne Beyer, Fabian Trillsch, Elisa Schmoeckel, Doris Mayr, Sven Mahner, Udo Jeschke, Anna Hester
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-16 (2021)
Abstract Background An abundance of tumor-associated macrophages has been shown to be an independent prognostic factor for a poor prognosis of human breast cancer (BC). Adipose tissue accounts for the largest proportion of the breast and has also bee
Externí odkaz:
https://doaj.org/article/b079fccf2b264727a13d7de0710e4203
Autor:
Nicole Elisabeth Topalov, Doris Mayr, Clemens Scherer, Anca Chelariu-Raicu, Susanne Beyer, Anna Hester, Fabian Kraus, Mingjun Zheng, Till Kaltofen, Thomas Kolben, Alexander Burges, Sven Mahner, Fabian Trillsch, Udo Jeschke, Bastian Czogalla
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The impact of Actin beta-like 2 (ACTBL2), a novel described actin isoform, on epithelial ovarian cancer (EOC) biology has not been investigated so far. In this study, we analyzed the prognostic and functional significance of ACTBL2 and its regulatory
Externí odkaz:
https://doaj.org/article/a8ab4bea62a044918dd18ca46829d427
Autor:
Stefan Kluge, Gernot Marx, Christian Putensen, Danny Ammon, Silke Haferkamp, Saskia Deffge, Thomas Wendt, Daniel Tiller, André Scherag, Philipp Simon, Johannes Bickenbach, Sebastian Johannes Fritsch, Julian Benedict Kunze, Oliver Maassen, Jennifer Kistermann, Irina Lutz, Nora Kristiana Voellm, Volker Lowitsch, Richard Polzin, Konstantin Sharafutdinov, Hannah Mayer, Lars Kuepfer, Rolf Burghaus, Walter Schmitt, Joerg Lippert, Morris Riedel, Chadi Barakat, André Stollenwerk, Simon Fonck, Sven Zenker, Felix Erdfelder, Daniel Grigutsch, Rainer Kram, Susanne Beyer, Knut Kampe, Jan Erik Gewehr, Friederike Salman, Patrick Juers, Emilia Wisotzki, Sebastian Gross, Lorenz Homeister, Frank Bloos, Susanne Mueller, Julia Palm, Nora Jahn, Markus Loeffler, Tobias Schuerholz, Petra Groeber, Andreas Schuppert
Publikováno v:
BMJ Open, Vol 11, Iss 4 (2021)
Introduction The acute respiratory distress syndrome (ARDS) is a highly relevant entity in critical care with mortality rates of 40%. Despite extensive scientific efforts, outcome-relevant therapeutic measures are still insufficiently practised at th
Externí odkaz:
https://doaj.org/article/16921f71636846b9984cf353bd67fb35
Autor:
Bastian Czogalla, Alexandra Partenheimer, Susann Badmann, Elisa Schmoeckel, Doris Mayr, Thomas Kolben, Susanne Beyer, Anna Hester, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100910- (2021)
Background:: Enolase-1, primarily known for its role in glucose metabolism, is overexpressed in various cancer entities. In contrast its alternative spliced nuclear isoform MBP-1 acts as a tumor suppressor. The aim of this study is to analyze the pro
Externí odkaz:
https://doaj.org/article/10b346fbbd114b0487ee2ccde22428e1
Autor:
Laura Hahn, Sarah Meister, Mareike Mannewitz, Susanne Beyer, Stefanie Corradini, Uwe Hasbargen, Sven Mahner, Udo Jeschke, Thomas Kolben, Alexander Burges
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 707 (2022)
Preeclampsia (PE) is a severe pregnancy disorder with a pathophysiology not yet completely understood and without curative therapy. The histone modifications H3K4me3 and H3K9ac, as well as galectin-2 (Gal-2), are known to be decreased in PE. To gain
Externí odkaz:
https://doaj.org/article/0835b14cf78240cd8d43b8b82f70132f
Autor:
Eileen Deuster, Ivi Hysenaj, Maja Kahaly, Elisa Schmoeckel, Doris Mayr, Susanne Beyer, Thomas Kolben, Anna Hester, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Cells, Vol 10, Iss 9, p 2337 (2021)
The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development. In this study, we aimed to evaluate
Externí odkaz:
https://doaj.org/article/fcf9a42f48fe4ba7a4a18d1a16d83e37