Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Susanne B. Schwedler"'
Autor:
Reinhard Schneider, Thomas Hansen-Hagge, János G. Filep, Christoph Wanner, Susanne B. Schwedler, Jan Galle, Matthias Reichert, Lawrence A. Potempa, Daniel Schmiedeke
Publikováno v:
Clinical Chemistry. 55:1728-1731
Background: C-reactive protein (CRP) is a risk marker for cardiovascular disease and has been implicated in atherogenesis. In atherosclerotic plaques, it colocalizes with oxidized LDL (oxLDL) and promotes oxLDL uptake by macrophages, suggesting an im
Autor:
Julian Widder, Peter J. Kuhlencordt, Gencay Hatiboglu, Susanne B. Schwedler, Jan Galle, Padmapriya Ponnuswamy, Christoph Wanner, T Quaschning, Lawrence A. Potempa
Publikováno v:
Atherosclerosis. 195:e76-e84
Objective: In addition to being a risk marker for cardiovascular disease, recent data suggests that C-reactive protein (CRP) induces endothelial dysfunction and promotes oxidative stress. We evaluated the effects of two conformers of CRP (pentameric,
Autor:
Konstanze Wernicke, Christoph Wanner, Alexander Krebs, Matthias Nauck, Susanne B. Schwedler, Kerstin Amann, Lawrence A. Potempa, Jan Galle
Publikováno v:
Circulation. 112:1016-1023
Background—C-reactive protein (CRP) may have proatherogenic but also vasoprotective properties. We tested the hypothesis that the configuration of CRP (pentameric, or native [nCRP], versus monomeric, or modified [mCRP]) determines these different c
Publikováno v:
Nephrology Dialysis Transplantation. 18:2300-2307
Background. Serum levels of C-reactive protein (CRP) increase during various atherosclerotic as well as kidney diseases. Whether CRP plays a pathophysiological role or rather serves as a marker is unknown. Here, we investigated the role of CRP in dia
Autor:
Liliane J. Striker, J. Vilar, M. F. Weiss, H. Bakala, Susanne B. Schwedler, P. Verbeke, E. Fourmaintraux, P. Depreux, Gary E. Striker
Publikováno v:
Diabetes, Obesity and Metabolism. 3:230-239
Summary Aims Advanced glycation end products (AGE), which form from the non-enzymatic reaction of proteins and sugars, have been implicated in the pathogenesis of diabetic nephropathy. Recently, a compound [N-phenacylthiazolium bromide (PTB)] has bee
Autor:
Carlos A. Vaamonde, Norma A. Bobadilla, Jaime Herrera-Acosta, Liliane J. Striker, Susanne B. Schwedler, Gary E. Striker
Publikováno v:
Transplantation. 68:1583-1588
Background Long-term cyclosporine (CsA) treatment leads to a decreased glomerular filtration rate, hyalinosis of afferent arterioles, and striped cortical tubulo-interstitial fibrosis. We showed previously that pentosan polysulfate (SP54) prevented t
Autor:
A Krämer-Guth, Nubia Kristen Kaba, Susanne B. Schwedler, Christoph Wanner, Florian Lang, Gillian L. Busch
Publikováno v:
American Journal of Physiology-Cell Physiology. 273:C1409-C1415
The present study has been performed to elucidate a possible role of cell volume in low-density lipoprotein (LDL) binding and internalization (LDLb+i). As shown previously, increase of extracellular osmolarity (OSMe) and K+depletion, both known to sh
Publikováno v:
Kidney International. 51:253-260
Atherogenic lipoproteins and reactive oxygen species stimulate renin release from isolated juxtaglomerular (JG) cells. Here we assessed whether stimulation of renin release is mediated by formation of superoxide anion (O2-), and whether the effects o
Publikováno v:
NDT Plus
Unravelling chronic hypokalaemia can be a clinical challenge in some patients. History and physical examination can be misleading or inaccurate. Diagnostic steps usually involve assessing urinary potassium excretion, transtubular potassium gradient (
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 47(2)
Based on a multitude of clinical studies, C-reactive protein (CRP) has emerged as a risk marker for the development of cardiovascular disease, leading to recently published recommendations for screening the general population for plasma CRP level as