Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Susanne A Raadsen"'
Autor:
Vadim Makarov, Benoit Lechartier, Ming Zhang, João Neres, Astrid M van der Sar, Susanne A Raadsen, Ruben C Hartkoorn, Olga B Ryabova, Anthony Vocat, Laurent A Decosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J Dyson, Stewart T Cole
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 3, Pp 372-383 (2014)
Abstract The benzothiazinone lead compound, BTZ043, kills Mycobacterium tuberculosis by inhibiting the essential flavo‐enzyme DprE1, decaprenylphosphoryl‐beta‐D‐ribose 2‐epimerase. Here, we synthesized a new series of piperazine‐containin
Externí odkaz:
https://doaj.org/article/7fcc7ed7ee8f414d915598d5dc239ac7
Autor:
M. Carla Piazzon, Ivona Mladineo, Fernando Naya-Català, Ron P. Dirks, Susanne Jong-Raadsen, Anamarija Vrbatović, Jerko Hrabar, Jaume Pérez-Sánchez, Ariadna Sitjà-Bobadilla
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Monogenean flatworms are the main fish ectoparasites inflicting serious economic losses in aquaculture. The polyopisthocotylean Sparicotyle chrysophrii parasitizes the gills of gilthead sea bream (GSB, Sparus aurata) causing anaem
Externí odkaz:
https://doaj.org/article/c1ea153482ac478cbf1a0dc5d1ee7b88
Autor:
Susanne Jong-Raadsen, Hans J. Jansen, W. Swinkels, Finn-Arne Weltzien, Alex Koelewijn, Sylvie Dufour, Christiaan V. Henkel, Herman P. Spaink, Bernd Pelster, Guido van den Thillart, Ron P. Dirks, Arjan P. Palstra, Michael Liem
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
This Article contains errors. Since the publication of this Article, the website hosting the assembly data has become inactive. The data has now been re-deposited in the DataverseNO repository. As such, the corrected Data Availability section should
Autor:
Susanne Jong-Raadsen, Jerko Hrabar, Ariadna Sitjà-Bobadilla, Ron P. Dirks, M. Carla Piazzon, Jaume Pérez-Sánchez, Anamarija Vrbatović, Ivona Mladineo, Fernando Naya-Català
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
BMC Genomics, Vol 20, Iss 1, Pp 1-16 (2019)
BMC Genomics
instname
BMC Genomics, Vol 20, Iss 1, Pp 1-16 (2019)
BMC Genomics
[Background] Monogenean flatworms are the main fish ectoparasites inflicting serious economic losses in aquaculture. The polyopisthocotylean Sparicotyle chrysophrii parasitizes the gills of gilthead sea bream (GSB, Sparus aurata) causing anaemia, lam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8e3b3e27d443cc945c86bd75ecabc3
http://hdl.handle.net/10261/178043
http://hdl.handle.net/10261/178043
Autor:
Finn-Arne Weltzien, Hans J. Jansen, Sylvie Dufour, Arjan P. Palstra, Susanne Jong-Raadsen, Guido van den Thillart, Michael Liem, Alex Koelewijn, Ron P. Dirks, Bernd Pelster, Herman P. Spaink, Christiaan V. Henkel, W. Swinkels
Publikováno v:
Scientific Reports 7 (2017) 1
Scientific Reports, 7(1)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, 7(1), 7213
Scientific Reports, 7(1)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, 7(1), 7213
We have sequenced the genome of the endangered European eel using the MinION by Oxford Nanopore, and assembled these data using a novel algorithm specifically designed for large eukaryotic genomes. For this 860 Mbp genome, the entire computational pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1929b3402663177b0dcf270d77747cd
https://doi.org/10.1101/101907
https://doi.org/10.1101/101907
Autor:
Susanne Jong-Raadsen, Jeroen Bakkers, Rubén Marín-Juez, Vanesa Jiménez-Amilburu, Herman P. Spaink
Publikováno v:
Journal of Endocrinology, 224(1), 1. Society for Endocrinology
The Journal of endocrinology, 224(1), 1-15. Society for Endocrinology
The Journal of endocrinology, 224(1), 1-15. Society for Endocrinology
Cardiomyopathies-associated metabolic pathologies (e.g., type 2 diabetes and insulin resistance) are a leading cause of mortality. It is known that the association between these pathologies works in both directions, for which heart failure can lead t
Autor:
N. al Naiemi, Jan Kluytmans, E. A. Reuland, Paul H. M. Savelkoul, Susanne A. Raadsen, Christina M. J. E. Vandenbroucke-Grauls
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
Reuland, E A, Naiemi, N, Raadsen, S A, Savelkoul, P H M, Kluijtmans, J A J W & Vandenbroucke-Grauls, C M J E 2014, ' Prevalence of ESBL-producing Enterobacteriaceae in raw vegetables ', European Journal of Clinical Microbiology and Infectious Diseases, vol. 33, no. 10, pp. 1843-1846 . https://doi.org/10.1007/s10096-014-2142-7
European Journal of Clinical Microbiology & Infectious Diseases, 33(10), 1843-1846. Springer, Cham
European Journal of Clinical Microbiology and Infectious Diseases, 33(10), 1843-1846. Springer Verlag
Reuland, E A, Naiemi, N, Raadsen, S A, Savelkoul, P H M, Kluijtmans, J A J W & Vandenbroucke-Grauls, C M J E 2014, ' Prevalence of ESBL-producing Enterobacteriaceae in raw vegetables ', European Journal of Clinical Microbiology and Infectious Diseases, vol. 33, no. 10, pp. 1843-1846 . https://doi.org/10.1007/s10096-014-2142-7
European Journal of Clinical Microbiology & Infectious Diseases, 33(10), 1843-1846. Springer, Cham
European Journal of Clinical Microbiology and Infectious Diseases, 33(10), 1843-1846. Springer Verlag
To determine whether extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) are present in retail raw vegetables in Amsterdam, the Netherlands, we collected 119 samples of 15 different types of vegetables from various sources.
Autor:
Thierry Buclin, Ruben C. Hartkoorn, Florence Pojer, Vadim Makarov, Astrid M. van der Sar, Laurent A. Decosterd, Anthony Vocat, Ming Zhang, O. B. Ryabova, Stewart T. Cole, Paul J. Dyson, Koen Andries, Benoit Lechartier, João Neres, Wilbert Bitter, Susanne A. Raadsen, Nicolas Widmer
Publikováno v:
Embo Molecular Medicine, vol. 6, no. 3, pp. 372-383
EMBO Molecular Medicine, Vol 6, Iss 3, Pp 372-383 (2014)
EMBO Molecular Medicine
Makarov, V, Lechartier, B, Zhang, M, Neres, J, van der Sar, A M, Raadsen, S A, Hartkoorn, R C, Ryabova, O B, Vocat, A, Decosterd, L A, Widmer, N, Buclin, T, Bitter, W, Andries, K, Pojer, F, Dyson, P J & Cole, S T 2014, ' Towards a new combination therapy for tuberculosis with next generation benzothiazinones ', Embo Molecular Medicine, vol. 6, no. 3, pp. 372-383 . https://doi.org/10.1002/emmm.201303575
Embo Molecular Medicine, 6(3), 372-383. Wiley-Blackwell
EMBO Molecular Medicine; Vol 6
EMBO Molecular Medicine, Vol 6, Iss 3, Pp 372-383 (2014)
EMBO Molecular Medicine
Makarov, V, Lechartier, B, Zhang, M, Neres, J, van der Sar, A M, Raadsen, S A, Hartkoorn, R C, Ryabova, O B, Vocat, A, Decosterd, L A, Widmer, N, Buclin, T, Bitter, W, Andries, K, Pojer, F, Dyson, P J & Cole, S T 2014, ' Towards a new combination therapy for tuberculosis with next generation benzothiazinones ', Embo Molecular Medicine, vol. 6, no. 3, pp. 372-383 . https://doi.org/10.1002/emmm.201303575
Embo Molecular Medicine, 6(3), 372-383. Wiley-Blackwell
EMBO Molecular Medicine; Vol 6
The benzothiazinone lead compound, BTZ043, kills Mycobacterium tuberculosis by inhibiting the essential flavo-enzyme DprE1, decaprenylphosphoryl-beta-D-ribose 2-epimerase. Here, we synthesized a new series of piperazine-containing benzothiazinones (P
Autor:
Theo Verboom, Gurdyal S. Besra, Astrid M. van der Sar, Arun K. Mishra, Marion Sparrius, Wilbert Bitter, Esther J. M. Stoop, Gunny van Stempvoort, Nicole N. van der Wel, Susanne A. Raadsen, Ben J. Appelmelk, Maaike van Zon, Nicole N. Driessen, Lisanne M. van Leeuwen, Pascale Bouchier, Jeroen Geurtsen
Publikováno v:
Cellular Microbiology. 15:2093-2108
The causative agent of tuberculosis (TB), Mycobacterium tuberculosis, remains an important worldwide health threat. Although TB is one of the oldest infectious diseases of man, a detailed understanding of the mycobacterial mechanisms underlying patho
Autor:
Edith N.G. Houben, Marion Sparrius, Aniek D. van der Woude, Jeroen Geurtsen, Susanne A. Raadsen, Louis Boon, Debasmita Sarkar, Astrid M. van der Sar, Joen Luirink, Apoorva Bhatt, Wilbert Bitter, Gurdyal S. Besra
Publikováno v:
Journal of Biological Chemistry, 287(24), 20417-20429. American Society for Biochemistry and Molecular Biology Inc.
van der Woude, A D, Sarkar, D, Bhatt, A, Sparrius, M, Raadsen, S A, Boon, L, Geurtsen, J J G, Houben, E N G, Besra, G S, Bitter, W, van der Sar, A M & Luirink, S 2012, ' Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum. ', Journal of Biological Chemistry, vol. 287, no. 24, pp. 20417-20429 . https://doi.org/10.1074/jbc.M111.336461
van der Woude, A D, Sarkar, D, Bhatt, A, Sparrius, M, Raadsen, S A, Boon, L, Geurtsen, J J G, Houben, E N G, Besra, G S, Bitter, W, van der Sar, A M & Luirink, S 2012, ' Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum. ', Journal of Biological Chemistry, vol. 287, no. 24, pp. 20417-20429 . https://doi.org/10.1074/jbc.M111.336461
The mycobacterial cell envelope is characterized by the presence of a highly impermeable second membrane, which is composed of mycolic acids intercalated with different unusual free lipids, such as lipooligosaccharides (LOS). Transport across this ce