Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Susanne, Kubetzko"'
Autor:
Christoph Aebi, Jasmin D Busch, Jochen Roessler, Franziska Suter-Riniker, Jean-Pierre Bourquin, Mutlu Kartal-Kaess, Susanne Kubetzko, Tobias M Dantonello
Publikováno v:
Dantonello, Tobias M.; Kartal-Kaess, Mutlu; Aebi, Christoph; Suter-Riniker, Franziska; Busch, Jasmin D.; Kubetzko, Susanne; Bourquin, Jean-Pierre; Roessler, Jochen (2021). SARS-CoV-2 Infection During Induction Chemotherapy in a Child With High-risk T-Cell Acute Lymphoblastic Leukemia (T-ALL). Journal of pediatric hematology/oncology, 43(6), e804-e807. Wolters Kluwer Health 10.1097/MPH.0000000000001943
Journal of Pediatric Hematology/Oncology
Journal of Pediatric Hematology/Oncology
The clinical course of SARS-CoV-2 infection (COVID-19) in children with hematologic malignancies is unclear. We describe the diagnosis, treatment and outcome of a 4-year-old boy with high-risk acute lymphoblastic leukemia and COVID-19. Regardless of
Autor:
Claus Meyer, Beat W. Schaefer, Patrizia Larghero, Bruno Almeida Lopes, Matthew J. Smith, Rolf Marschalek, Rosemary Sutton, Aurélie Caye-Eude, Hélène Cavé, Nicola C. Venn, Mariana Emerenciano, Marius Külp, Susanne Kubetzko, Karin Nebral, Giovanni Cazzaniga, Grazia Fazio
Publikováno v:
Blood. 138:3327-3327
Chromosomal rearrangements of the KMT2A gene are associated with acute leukemias and myelodysplastic syndromes. The large number of known KMT2A fusions (>100) renders a precise diagnosis a demanding task. More than 50% of all KMT2A partner genes have
Publikováno v:
Journal of Biological Chemistry. 281:35186-35201
A major goal in antibody design for cancer therapy is to tailor the pharmacokinetic properties of the molecule according to specific treatment requirements. Key parameters determining the pharmacokinetics of therapeutic antibodies are target specific
Publikováno v:
Molecular Pharmacology. 68:1439-1454
PEGylation is an attractive strategy to enhance the therapeutic efficacy of proteins with a short serum half-life. It can be used to extend the serum persistence and to reduce the immunogenicity of proteins. However, PEGylation can also lead to a dec
Autor:
Claudia Stahl, Harald Engelhardt, Susanne Kubetzko, Iris Kaps, Michael Niederweis, Silke Seeber
Publikováno v:
Molecular Microbiology. 40:451-464
MspA is an extremely stable, oligomeric porin from Mycobacterium smegmatis that forms water-filled channels in vitro. Immunogold electron microscopy and an enzyme-linked immunosorbent assay demonstrated that MspA is localized in the cell wall. An msp
Publikováno v:
The Journal of biological chemistry. 281(46)
A major goal in antibody design for cancer therapy is to tailor the pharmacokinetic properties of the molecule according to specific treatment requirements. Key parameters determining the pharmacokinetics of therapeutic antibodies are target specific
Autor:
Claudio, Di Paolo, Jörg, Willuda, Susanne, Kubetzko, Ikar, Lauffer, Dominique, Tschudi, Robert, Waibel, Andreas, Plückthun, Rolf A, Stahel, Uwe, Zangemeister-Wittke
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(7)
Epithelial cell adhesion molecule (Ep-CAM) is a tumor-associated antigen overexpressed in many solid tumors but shows limited expression in normal epithelial tissues. To exploit this favorable expression pattern for targeted cancer therapy, an Ep-CAM
Autor:
P. August Schubiger, Susanne Kubetzko, Jörg Willuda, Uwe Zangemeister-Wittke, Andreas Plückthun, Robert Waibel
Publikováno v:
ResearcherID
Multimerization of antibody fragments increases the valency and the molecular weight, both identified as key features in the design of the optimal targeting molecule. Here, we report the construction of mono-, di-, and tetrameric variants of the anti
Autor:
Claudia Stahl, Susanne Kubetzko, Iris Kaps, Silke Seeber, Harald Engelhardt, Michael Niederweis
Publikováno v:
Molecular Microbiology. 57:1509-1509