Does perfluorooctane sulfonate (PFOS) act as chemosensitizer in zebrafish embryos?

Autor: Dirk Skutlarek, Magnus Engwall, Peggy Wellner, Thomas Braunbeck, Britta Kais, Steffen Keiter, Kathleen Burkhardt-Medicke, Till Luckenbach, Harald Färber, Susanne Keiter

Publikováno v: Science of The Total Environment. :317-324

Earlier studies have shown that perfluorooctane sulfonate (PFOS) increases the toxicity of other chemicals by enhancing their uptake by cells and tissues. The present study aimed at testing whether the underlying mechanism of enhanced uptake of chemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2846c415128fc03e854eab88dcaef98
https://doi.org/10.1016/j.scitotenv.2015.12.089

The maturity index as a tool to facilitate the interpretation of changes in vitellogenin production and sex ratio in the Fish Sexual Development Test

Autor: Susanne Keiter, Thomas Braunbeck, Karin Lund Kinnberg, Susanne Knörr, Lisa Baumann, Henrik Holbech, Tina Nagel

Publikováno v: Baumann, L, Holbech, H, Keiter, S, Kinnberg, K L, Knörr, S, Nagel, T & Braunbeck, T 2013, ' The maturity index as a tool to facilitate the interpretation of changes in vitellogenin production and sex ratio in the Fish Sexual Development Test ', Aquatic Toxicology, vol. 128– 129, pp. 34– 42 . https://doi.org/10.1016/j.aquatox.2012.11.016

In July 2011, the Fish Sexual Development Test (FSDT) has officially been adopted as OECD test guideline 234 for the detection of endocrine disrupting chemicals (EDCs). Sex ratio and vitellogenin (VTG) induction are the mandatory endocrine endpoints

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8173e31774a69b3b887e917e43721360
https://doi.org/10.1016/j.aquatox.2012.11.016

Prochloraz causes irreversible masculinization of zebrafish (Danio rerio)

Autor: Thomas Braunbeck, Lisa Baumann, Tina Nagel, Helmut Segner, Susanne Knörr, Susanne Keiter

Publikováno v: Baumann, Lisa Annie; Knörr, Susanne; Keiter, Susanne; Nagel, Tina; Segner, Helmut; Braunbeck, Thomas (2015). Prochloraz causes irreversible masculinization of zebrafish (Danio rerio). Environmental science and pollution research, 22(21), pp. 16417-16422. Springer 10.1007/s11356-014-3486-3

The aim of the present study was to investigate the persistence of endocrine effects by prochloraz, a fungicide known to have multiple effects on the endocrine system of vertebrates. Since discontinuous exposure is particularly relevant in aquatic ec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba82672bcb318bfc8a541ff8915c924
https://pubmed.ncbi.nlm.nih.gov/25163568

Reversibility of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the estrogen 17α-ethinylestradiol

Autor: Martina Fenske, Viktoria Schiller, Lisa Baumann, Sina Volz, Helmut Segner, Susanne Knörr, Susanne Keiter, Kristina Rehberger, Henrik Holbech, Thomas Braunbeck

Publikováno v: Baumann, L, Knörr, S, Keiter, S, Rehberger, K, Volz, S, Schiller, V, Fenske, M, Holbech, H, Segner, H & Braunbeck, T 2014, ' Reversibility of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the estrogen 17α-ethinylestradiol ', Toxicology and Applied Pharmacology, vol. 278, no. 3, pp. 230-237 . https://doi.org/10.1016/j.taap.2014.04.025

The aim of the present study was to investigate the persistence of the feminizing effects of discontinued 17alpha-ethinylestradiol (EE2) exposure on zebrafish (Danio rerio). An exposure scenario covering the sensitive phase of sexual differentiation,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c11f4520938ab38fb02e2f5e83d408
https://pubmed.ncbi.nlm.nih.gov/24832493

Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio)

Autor: Thomas Braunbeck, Harald Färber, Dirk Skutlarek, Lisa Baumann, Henrik Holbech, Susanne Keiter, Magnus Engwall

Publikováno v: Keiter, S, Baumann, L, Farber, H, Holbech, H, Skutlarek, D, Engwall, M & Braunbeck, T 2012, ' Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio). ', Aquatic Toxicology, vol. 118-119, pp. 116-129 . https://doi.org/10.1016/j.aquatox.2012.04.003

Previous in vitro studies have reported the potential of perfluorooctane sulfonate (PFOS) to increase the toxicity of other compounds. Given the complex nature of mixtures of environmental pollutants in aquatic systems together with the persistent an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662e90bea968c64cfd89eb0982fc5b29
https://portal.findresearcher.sdu.dk/da/publications/633a4e65-827f-4062-8b33-3ded0998cd8c