Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Susanne, Hermanns"'
Autor:
Hans Werner Müller, Susanne Hermanns
Publikováno v:
Brain Research Protocols. 7:162-167
After traumatic injury, adult central nervous system (CNS) axons fail to regenerate. We have previously shown that one major impediment for axon regeneration is the basement membrane (BM) forming at the lesion center, by means of a wound healing coll
Publikováno v:
Glia. 28:156-165
In a previous study, we have shown that microtransplanted Schwann cell suspensions foster structural recovery of the acutely transected postcommissural fornix. The emphasis of the present study was to examine whether subacutely and chronically injure
Autor:
Heike Niermann, Donatella D'Urso, Heiko J. Luhmann, Friederike Lausberg, Gisela Servos, Hans-Georg Hartwig, Hans Werner Müller, Susanne Hermanns, Christine C. Stichel
Publikováno v:
European Journal of Neuroscience. 11:632-646
Scarring impedes axon regrowth across the lesion site and is one major extrinsic constraint to effective regeneration in the adult mammalian central nervous system. In the present study we determined whether specific biochemical or immunochemical mod
Autor:
Christine C. Stichel, Gilbert Wunderlich, H. W. Müller, Claudia Rosenbaum, Susanne Hermanns, Clemens Oliver Hanemann
Publikováno v:
Glia. 21:299-314
Previous studies have shown that Schwann cell implantation offers a potential therapeutic approach to a variety of neurodegenerative disorders and traumatic injuries. In a clinically relevant paradigm, however, the implantation of autologous Schwann
Autor:
Phillip Schönle, Elke Guenther, Hans-Werner Mueller, Frank Werdin, Max Haerle, Frederica Di Scipio, Nektarios Sinis, Carmen Masanneck, Hans-Eberhard Schaller, Susanne Hermanns, Armin Kraus, Guido Koopmanns, Stefano Geuna, Timm Danker
Publikováno v:
Restorative neurology and neuroscience. 27(6)
Purpose: The improvement of regeneration and functional recovery after peripheral nerve injury is a major challenge in neurosurgery. Although microsurgical techniques for nerve reconstruction have seen great advancements over the last years, the clin
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780306478598
Following traumatic injuries of the central nervous system (CNS) a wound healing scar, resembling the molecular structure of a basement membrane and mainly composed of Collagen type IV and associated glycoproteins and proteoglycans, is formed. It is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffe113b1b0b7a5007c7ed8863ae01c1c
https://doi.org/10.1007/0-387-30128-3_11
https://doi.org/10.1007/0-387-30128-3_11
Publikováno v:
Advances in experimental medicine and biology. 557
Following traumatic injuries of the central nervous system (CNS) a wound healing scar, resembling the molecular structure of a basement membrane and mainly composed of Collagen type IV and associated glycoproteins and proteoglycans, is formed. It is
Autor:
Hans Werner Müller, Frank P.T. Hamers, Guido Straten, Susanne Hermanns, Werner Zuschratter, Daniela Müller, Simone Duis, Carmen Masanneck, Nicole Klapka
Publikováno v:
The European journal of neuroscience. 22(12)
Traumatic injury of the central nervous system results in formation of a collagenous basement membrane-rich fibrous scar in the lesion centre. Due to accumulation of numerous axon-growth inhibitory molecules the lesion scar is considered a major impe
Publikováno v:
Restorative neurology and neuroscience. 15(1)
After injury of the adult mammalian CNS axonal regeneration across or around the lesion scar is negligible. Previously, we have shown that the lesion-induced basal membrane (BM) within the lesion center participates in a growth barrier for axon regen
Autor:
Hans-Wilhelm Müller, Friederike Lausberg, Susanne Hermanns, Christine C. Stichel, H. Niermann, Donatella D'Urso
Publikováno v:
Neuroscience. 93(1)
The lesion scar formed after CNS injury is an impediment to axonal regeneration and leads to growth arrest or misrouting of sprouting axons. Our previous study showed that pharmacological reduction of basal membrane formation within the scar can over