Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Susanne, Fuessel"'
Autor:
Justus Simon Israel, Laura-Maria Marcelin, Christian Thomas, Eva Szczyrbová, Susanne Fuessel, Martin Puhr, Johannes Linxweiler, Shivani Yalala, Wilbert T. Zwart, Aria Baniahmad, Jasper van Goubergen, Harri M. Itkonen, Adam Sharp, Edward O’Neill, Marc Pretze, Matthias Miederer, Holger H.H. Erb
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Continued exploration of the androgen receptor (AR) is crucial, as it plays pivotal roles in diverse diseases such as prostate cancer (PCa), serving as a significant therapeutic focus. Therefore, the Department of Urology Dresden hosted an i
Externí odkaz:
https://doaj.org/article/39e0ffdb610b4782878eda81fbb46bd2
Autor:
Dinah Linke, Lukas Donix, Claudia Peitzsch, Holger H. H. Erb, Anna Dubrovska, Manuel Pfeifer, Christian Thomas, Susanne Fuessel, Kati Erdmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 666 (2022)
Docetaxel (DTX) is a mainstay in the treatment of metastatic prostate cancer. Failure of DTX therapy is often associated with multidrug resistance caused by overexpression of efflux membrane transporters of the ABC family such as the glycoprotein ABC
Externí odkaz:
https://doaj.org/article/e6f8e7868a164829a0c4b73361f74359
Autor:
Nico Dreymann, Julia Wuensche, Wiebke Sabrowski, Anja Moeller, Denise Czepluch, Dana Vu Van, Susanne Fuessel, Marcus M. Menger
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4890 (2022)
Urokinase-type plasminogen activator is widely discussed as a marker for cancer prognosis and diagnosis and as a target for cancer therapies. Together with its receptor, uPA plays an important role in tumorigenesis, tumor progression and metastasis.
Externí odkaz:
https://doaj.org/article/c325874f0a6f49eabb93a5d44d91e825
Autor:
Holger H H Erb, Julia Bodenbender, Florian Handle, Tamara Diehl, Lukas Donix, Igor Tsaur, Martin Gleave, Axel Haferkamp, Johannes Huber, Susanne Fuessel, Eva Juengel, Zoran Culig, Christian Thomas
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237248 (2020)
Despite enzalutamide's efficacy in delaying the progression of metastatic castration-resistant prostate cancer (CRPC), resistance to this anti-androgen inevitably occurs. Several studies have revealed that the signal transducer and activator of trans
Externí odkaz:
https://doaj.org/article/4e67266c59d74563ae1dc628b1acd121
Autor:
Alexander Schulz, Ielizaveta Gorodetska, Rayk Behrendt, Susanne Fuessel, Kati Erdmann, Sarah Foerster, Kaustubh Datta, Thomas Mayr, Anna Dubrovska, Michael H. Muders
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Neuropilin-2 (NRP2) is a prognostic indicator for reduced survival in bladder cancer (BCa) patients. Together with its major ligand, vascular endothelial growth factor (VEGF)-C, NRP2 expression is a predictive factor for treatment outcome in response
Externí odkaz:
https://doaj.org/article/a885c977c66443608873400f9081394f
Autor:
Doreen Huebner, Christiane Rieger, Ralf Bergmann, Martin Ullrich, Sebastian Meister, Marieta Toma, Ralf Wiedemuth, Achim Temme, Vladimir Novotny, Manfred P. Wirth, Michael Bachmann, Jens Pietzsch, Susanne Fuessel
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Novel theranostic options for high-risk non-muscle invasive bladder cancer are urgently needed. This requires a thorough evaluation of experimental approaches in animal models best possibly reflecting human disease before entering
Externí odkaz:
https://doaj.org/article/e4d4a9d9273b4e6d8aaeae60eba0d2d6
Autor:
Bastian Keck, Angelika Borkowetz, Julia Poellmann, Thilo Jansen, Moritz Fischer, Susanne Fuessel, Andreas Kahlmeyer, Manfred Wirth, Johannes Huber, Alexander Cavallaro, Matthias Hammon, Ivan Platzek, Arndt Hartmann, Gustavo Baretton, Frank Kunath, Danijel Sikic, Helge Taubert, Bernd Wullich, Kati Erdmann, Sven Wach
Publikováno v:
Cells, Vol 10, Iss 6, p 1315 (2021)
Multiparametric MRI (mpMRI) and targeted biopsy of the prostate enhance the tumor detection rate. However, the prediction of clinically significant prostate cancer (PCa) is still limited. Our study tested the additional value of serum levels of selec
Externí odkaz:
https://doaj.org/article/a71bd8aa6f6e4272b3d8ca217a30143f
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 8, Iss 1, Pp 1307-1317 (2017)
We have previously shown that carbon nanofibers (CNFs) and carbon nanotubes (CNTs) can sensitize prostate cancer (PCa) cells to platinum-based chemotherapeutics. In order to further verify this concept and to avoid a bias, the present study investiga
Externí odkaz:
https://doaj.org/article/eb63cc11343740d2bd7cda1ec3a2d4da
Autor:
Anna Dubrovska, Michael Baumann, Mechthild Krause, Manfred P. Wirth, Kati Erdmann, Susanne Fuessel, Stephen Lyle, Karl Simin, John R. Walker, Eduard A. Stakhovsky, Gennady D. Telegeev, Leoni A. Kunz-Schughart, Franziska Trautmann, Ina Kurth, Claudia Peitzsch, Monica Cojoc
Radiotherapy is a curative treatment option in prostate cancer. Nevertheless, patients with high-risk prostate cancer are prone to relapse. Identification of the predictive biomarkers and molecular mechanisms of radioresistance bears promise to impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4778c930451873071912c17d9c4553
https://doi.org/10.1158/0008-5472.c.6507572.v1
https://doi.org/10.1158/0008-5472.c.6507572.v1
Autor:
Anna Dubrovska, Michael Baumann, Mechthild Krause, Manfred P. Wirth, Kati Erdmann, Susanne Fuessel, Stephen Lyle, Karl Simin, John R. Walker, Eduard A. Stakhovsky, Gennady D. Telegeev, Leoni A. Kunz-Schughart, Franziska Trautmann, Ina Kurth, Claudia Peitzsch, Monica Cojoc
Supplementary Methods, Table 1, Figure S1-S9 (i) supplementary methods: Human tumor tissue dissociation, Immunofluorescence microscopy, Clonogenic cell survival assay, Sphere formation assay, Cell proliferation and cytotoxicity assay, Wound healing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17b41bafd798e6b8bc08b5312e29b6e
https://doi.org/10.1158/0008-5472.22408619
https://doi.org/10.1158/0008-5472.22408619