Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Susanne, Bens"'
Autor:
Anja Fischer, Thomas K. Albert, Natalia Moreno, Marta Interlandi, Jana Mormann, Selina Glaser, Paurnima Patil, Flavia W. de Faria, Mathis Richter, Archana Verma, Sebastian T. Balbach, Rabea Wagener, Susanne Bens, Sonja Dahlum, Carolin Göbel, Daniel Münter, Clara Inserte, Monika Graf, Eva Kremer, Viktoria Melcher, Gioia Di Stefano, Raffaella Santi, Alexander Chan, Ahmet Dogan, Jonathan Bush, Martin Hasselblatt, Sylvia Cheng, Signe Spetalen, Alexander Fosså, Wolfgang Hartmann, Heidi Herbrüggen, Stella Robert, Florian Oyen, Martin Dugas, Carolin Walter, Sarah Sandmann, Julian Varghese, Claudia Rossig, Ulrich Schüller, Alexandar Tzankov, Martin B. Pedersen, Francesco A. d’Amore, Karin Mellgren, Udo Kontny, Venkatesh Kancherla, Luis Veloza, Edoardo Missiaglia, Virginie Fataccioli, Philippe Gaulard, Birgit Burkhardt, Oliver Soehnlein, Wolfram Klapper, Laurence de Leval, Reiner Siebert, Kornelius Kerl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous group of malignancies with poor outcome. Here, we identify a subgroup, PTCL-NOS SMARCB1- , which is characterized by the lack of the SMARCB1 protein and occurs
Externí odkaz:
https://doaj.org/article/f9838f5a5f15480799585f8fa2420a7e
Autor:
Alexandra G. Kouroukli, Nivethika Rajaram, Pavel Bashtrykov, Helene Kretzmer, Reiner Siebert, Albert Jeltsch, Susanne Bens
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Activation of dominant oncogenes by small or structural genomic alterations is a common driver mechanism in many cancers. Silencing of such dominantly activated oncogenic alleles, thus, is a promising strategy to treat cancer. Rec
Externí odkaz:
https://doaj.org/article/11af78ae09f44988a6a8dbb6e2a1f3dd
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-18 (2023)
Abstract Background Epigenome editing refers to the targeted reprogramming of genomic loci using an EpiEditor which may consist of an sgRNA/dCas9 complex that recruits DNMT3A/3L to the target locus. Methylation of the locus can lead to a modulation o
Externí odkaz:
https://doaj.org/article/41d1de7855f14d409bafb99c8a958394
Autor:
Alexandra G. Kouroukli, Anja Fischer, Helene Kretzmer, Emil Chteinberg, Nivethika Rajaram, Selina Glaser, Julia Kolarova, Pavel Bashtrykov, Stephan Mathas, Hans G. Drexler, Hitoshi Ohno, Ole Ammerpohl, Albert Jeltsch, Reiner Siebert, Susanne Bens
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/a5d245bc7209422783c3ec33c962c0d4
Autor:
Ross A. Jackson, Victoria M. Smith, Sandrine Jayne, Cosima Drewes, Susanne Bens, Reiner Siebert, Martin J. S. Dyer, Harriet S. Walter
Publikováno v:
HemaSphere, Vol 6, Iss 8, p e752 (2022)
Externí odkaz:
https://doaj.org/article/1cee28801af24264960f73131ada3e1a
Autor:
Shaymaa Elgaafary, Inga Nagel, Cristina López, Susanne Bens, Monika Szczepanowski, Rabea Wagener, Wolfram Klapper, Reiner Siebert
Publikováno v:
Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-4 (2020)
Abstract Background Whereas lymphoma of the female breast is already rare, lymphoma of the male breast has only anecdotally been reported. Within a study of 32 lymphoma of the breast reported between 1973 and 2014 as Burkitt lymphoma, we observed a s
Externí odkaz:
https://doaj.org/article/d70cbddadab64b4f91c2decbfc694920
Autor:
Cristina Lopez, Nikolai Schleussner, Stephan H. Bernhart, Kortine Kleinheinz, Stephanie Sungalee, Henrike L. Sczakiel, Helene Kretzmer, Umut H. Toprak, Selina Glaser, Rabea Wagener, Ole Ammerpohl, Susanne Bens, Maciej Giefing, Juan C. Gonzalez Sanchez, Gordana Apic, Daniel Hubschmann, Martin Janz, Markus Kreuz, Anja Mottok, Judith M. Muller, Julian Seufert, Steve Hoffmann, Jan O. Korbel, Robert B. Russell, Roland Schule, Lorenz Trumper, Wolfram Klapper, Bernhard Radlwimmer, Peter Lichter, Ralf Kuppers, Matthias Schlesner, Stephan Mathas, Reiner Siebert
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
Histone methylation-modifiers, such as EZH2 and KMT2D, are recurrently altered in B-cell lymphomas. To comprehensively describe the landscape of alterations affecting genes encoding histone methylation-modifiers in lymphomagenesis we investigated who
Externí odkaz:
https://doaj.org/article/3d3b5d4cbb534e4eb3816d334f4e9a3c
Autor:
Branavan Manoranjan, MD, PhD, Yves P. Starreveld, MD, PhD, Robert A. Nordal, MSC, MD, FRCPC, Christopher Dunham, MD, FRCPC, Susanne Bens, MD, Christian Thomas, MD, Martin Hasselblatt, MD, Jeffrey T. Joseph, MD, PhD
Publikováno v:
Free Neuropathology, Vol 2 (2021)
We present a young adult woman who developed a myxoid tumor of the pineal region having a SMARCB1 mutation, which was phenotypically similar to the recently described desmoplastic myxoid, SMARCB1-mutant tumor of the pineal region (DMT-SMARCB1). The 2
Externí odkaz:
https://doaj.org/article/fff7e7e268b8466db7167647569f68de
Autor:
Rabea Wagener, Susanne Bens, Umut H. Toprak, Julian Seufert, Cristina López, Ingrid Scholz, Heidi Herbrueggen, Ilske Oschlies, Stephan Stilgenbauer, Matthias Schlesner, Wolfram Klapper, Birgit Burkhardt, Reiner Siebert
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
Externí odkaz:
https://doaj.org/article/ce3b2800f06b434488e843366fdb2d43
Autor:
Susanne Bens, Manuel Luedeke, Tanja Richter, Melanie Graf, Julia Kolarova, Gotthold Barbi, Krisztian Lato, Thomas F. Barth, Reiner Siebert
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-9 (2017)
Abstract Background Uniparental disomy of certain chromosomes are associated with a group of well-known genetic syndromes referred to as imprinting disorders. However, the extreme form of uniparental disomy affecting the whole genome is usually not c
Externí odkaz:
https://doaj.org/article/fea17602ea834af980013c8a43f06d89