Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Susannah Havermann"'
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
Flavonoids are secondary plant compounds that mediate diverse biological activities, for example, by scavenging free radicals and modulating intracellular signalling pathways. It has been shown in various studies that distinct flavonoid compounds enh
Externí odkaz:
https://doaj.org/article/5a9d669f53254c7a91b4c47e677d26b9
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100256 (2014)
CAPE is an active constituent of propolis which is widely used in traditional medicine. This hydroxycinnamic acid derivate is a known activator of the redox-active Nrf2 signalling pathway in mammalian cells. We used C. elegans to investigate the effe
Externí odkaz:
https://doaj.org/article/ec6cdedd89cd48849f0e7e40e6c95c2e
Publikováno v:
Pharmaceutical Biology. 54:1491-1502
Baicalein is a major compound in extracts derived from Scutellaria baicalensis Georgi (Lamiaceae) which are used in the Traditional Chinese Medicine for the treatment of inflammatory and gastrointestinal diseases. This flavonoid is an activator of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8327eb28b0c08ebdd28312b2f985b6
https://doi.org/10.3109/13880209.2015.1104703
https://doi.org/10.3109/13880209.2015.1104703
Autor:
Christian Büchter, Wera Döring, Patrick B. Chalo Mutiso, Karoline Koch, Claus M. Passreiter, Wim Wätjen, Gabriel Schulz, Susannah Havermann
Publikováno v:
The Journal of pharmacy and pharmacology. 71(6)
Objectives Recent studies showed that distinct extracts of Erythrina species used in the traditional medicine of sub-Saharan Africa are protective against stress conditions. However, the underlying molecular mechanisms as well as relevant compounds r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6e13b632f6be1aa2cb36e6d3dc561c
https://pubmed.ncbi.nlm.nih.gov/30793315
https://pubmed.ncbi.nlm.nih.gov/30793315
Publikováno v:
Phytotherapy Research. 29:894-901
The lignan pinoresinol is a constituent of flaxseed, sesame seeds and olive oil. Because of different molecular effects reported for this compound, e.g. antioxidative activity, pinoresinol is suggested to cause positive effects on humans. Because exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf49cf737e73ed75946440066cb83095
https://doi.org/10.1002/ptr.5330
https://doi.org/10.1002/ptr.5330
Autor:
Susannah Havermann, Karoline Koch, Christian Büchter, N. Arnold, Wim Wätjen, D. Ackermann, Sebastian Honnen
Publikováno v:
Food & Function. 6:3383-3392
Only certain flavonoids have been shown to enhance life span. This was pointed out for e.g. myricetin in the nematode Caenorhabditis elegans. However, the structural requirements responsible for this effect are not known. We used methylated derivativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec08f897184c0bac7bf943f8a10da78
https://doi.org/10.1039/c5fo00463b
https://doi.org/10.1039/c5fo00463b
Autor:
Susannah Havermann, Christian Büchter, Wim Wätjen, Daniela Ackermann, Yvonni Chovolou, Andreas Kampkötter, Gerhard Fritz, Sebastian Honnen
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 6, Pp 11895-11914 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 6; Pages: 11895-11914
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 14; Issue 6; Pages: 11895-11914
Myricetin is a naturally occurring flavonol found in many plant based food sources. It increases the lifespan of Caenorhabditis elegans, but the molecular mechanisms are not yet fully understood. We have investigated the impact of this flavonoid on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c03246c7b9919b9b1de4fff45606a7
http://www.mdpi.com/1422-0067/14/6/11895
http://www.mdpi.com/1422-0067/14/6/11895
Publikováno v:
Journal of Agricultural and Food Chemistry. 61:2158-2164
Baicalein is a major compound of extracts derived from Scutellaria baicalensis Lamiaceae, which are used as food supplements. Baicalein possesses a high radical scavenging activity and decreases intracellular reactive oxygen species in Hct116 human c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ad5d5db3813e96583c7b790066835e
https://doi.org/10.1021/jf304553g
https://doi.org/10.1021/jf304553g
Publikováno v:
Fitoterapia. 113
The flavonoid baicalein has been demonstrated to be an activator of the transcription factor Nrf2 in mammalian cell lines. We show that it further modulates the Nrf2 homolog SKN-1 in Caenorhabditis elegans and by this pathway mediates beneficial effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feeb1b20f60b5d0a213478b6ba70fbd8
https://pubmed.ncbi.nlm.nih.gov/27370100
https://pubmed.ncbi.nlm.nih.gov/27370100
Publikováno v:
Oxidative Stress in Applied Basic Research and Clinical Practice ISBN: 9783319190952
Oxidative stress contributes to the process of carcinogenesis in several ways: an oxidation of DNA bases by reactive oxygen species (ROS), e.g. oxidation of guanosine to 8-hydroxyguanosine, has been linked to the formation of mutations thereby trigge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4e6ba86206bc5323443de03df12bb48
https://doi.org/10.1007/978-3-319-19096-9_9
https://doi.org/10.1007/978-3-319-19096-9_9
