Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Susannah Cleary"'
Autor:
Clearys@ninds.nih.gov, Susannah Cleary
Chromaffin cells are a modified post-ganglionic sympathetic neuron, which synthesise and secrete catecholamines. The neoplastic transformation of chromaffin cells is demonstrated by the tumour phaeochromocytoma, a functional tumour that recapitulates
Autor:
Jennifer J. Barb, Jacqueline K. Phillips, Susannah Cleary, Abdel G. Elkahloun, David S. Goldstein, Robert Worrell, Thanh T. Huynh, Karel Pacak, Graeme Eisenhofer
Publikováno v:
Journal of Endocrinology. 193:225-233
Phaeochromocytomas are rare neuroendocrine tumours that produce catecholamines and numerous secretory proteins and peptides, including neuropeptide Y (NPY), a vasoactive peptide with influences on blood pressure. The production of catecholamines and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200fdd0b9776d837d8a3bd556a7d030f
https://doi.org/10.1677/joe-06-0138
https://doi.org/10.1677/joe-06-0138
Autor:
Brenda A. Klaunberg, James F. Powers, Daniel Schimel, Edwin W. Lai, Karel Pacak, Shoichiro Ohta, Douglas A. Bakan, John C. Morris, Susannah Cleary, Arthur S. Tischler, Mones Abu-Asab
Publikováno v:
International Journal of Cancer. 119:2236-2241
Successful outcomes for patients with cancer often depend on the early detection of tumor and the prompt initiation of active therapy. Despite major advances in the treatment of many cancers, early-stage lesions often go undetected due to the subopti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31cf1519f7b49f31f77d393da90a8a7d
https://doi.org/10.1002/ijc.22127
https://doi.org/10.1002/ijc.22127
Autor:
Thanh-Truc Huynh, Graeme Eisenhofer, Frederieke M. Brouwers, Mones Abu-Asab, Susannah Cleary, Robert Worrell, David S. Goldstein, Abdel G. Elkahloun, Macclellan M. Walther, Karel Pacak
Publikováno v:
European Journal of Endocrinology. 153:551-563
Objective: Phaeochromocytomas in patients with multiple endocrine neoplasia type 2 (MEN 2) produce adrenaline, whereas those with von Hippel-Lindau (VHL) syndrome do not. This study assessed whether these distinctions relate to differences in express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400b5c3a2d365b5db0f46313249618b6
https://doi.org/10.1530/eje.1.01987
https://doi.org/10.1530/eje.1.01987
Autor:
Lucia Martiniova, Jurgen Seidel, Dale O. Kiesewetter, David Thomasson, Susannah Cleary, Richard Kvetnansky, Linda F. Dawson, Jacqueline K. Phillips, Xiaoyuan Chen, James F. Powers, Graeme Eisenhofer, Edwin W. Lai, Karel Pacak
Publikováno v:
Nuclear medicine and biology. 39(2)
To evaluate the usefulness of [(18)F]-6-fluorodopamine ([(18)F]-DA) and [(18)F]-L-6-fluoro-3,4-dihydroxyphenylalanine ([(18)F]-DOPA) positron emission tomography (PET) in the detection of subcutaneous (s.c.) and metastatic pheochromocytoma in mice; t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51e6cc4b5690742b8366b4b00f45d7e
https://pubmed.ncbi.nlm.nih.gov/21958851
https://pubmed.ncbi.nlm.nih.gov/21958851
Autor:
Susannah Cleary, Bernhard Manz, Richard Kvetnansky, Peter Vargovic, Marcela Laukova, Karel Pacak, Jozef Ukropec
Publikováno v:
FEBS letters. 585(14)
Catecholamines are an important regulator of lipolysis in adipose tissue. Here we show that rat adipocytes, isolated from mesenteric adipose tissue, express genes of catecholamine biosynthetic enzymes and produce catecholamines de novo. Administratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d507a762936622374fd767572ca8f5c5
https://pubmed.ncbi.nlm.nih.gov/21689652
https://pubmed.ncbi.nlm.nih.gov/21689652
Autor:
Thanh-Truc Huynh, Karel Pacak, Robert Worrell, Jacqueline K. Phillips, Peter J. Munson, Susannah Cleary, Graeme Eisenhofer, S. Fliedner, Abdel G. Elkahloun
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 39(12)
Chromogranin A (CGA) is a major secretory protein present in the soluble matrix of chromaffin granules of neuroendocrine cells and tumours, such as phaeochromocytomas. CGA has several functions, some of which may be involved in the distinct phenotypi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78eaccd0ad33abbe333584af35fc7fdd
https://pubmed.ncbi.nlm.nih.gov/18046660
https://pubmed.ncbi.nlm.nih.gov/18046660
Publikováno v:
Annals of the New York Academy of Sciences. 1073
Pheochromocytomas are rare neuroendocrine tumors of chromaffin cell origin that synthesize and secrete excess quantities of catecholamines and other vasoactive peptides. Pheochromocytomas also express the norepinephrine transporter (NET), a molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9aca61f5ec23b8d8affe8d0c9b5d890
https://pubmed.ncbi.nlm.nih.gov/17102094
https://pubmed.ncbi.nlm.nih.gov/17102094
Autor:
Shoichiro, Ohta, Edwin W, Lai, John C, Morris, Douglas A, Bakan, Brenda, Klaunberg, Susannah, Cleary, James F, Powers, Arthur S, Tischler, Mones, Abu-Asab, Daniel, Schimel, Karel, Pacak
Publikováno v:
International journal of cancer. 119(9)
Successful outcomes for patients with cancer often depend on the early detection of tumor and the prompt initiation of active therapy. Despite major advances in the treatment of many cancers, early-stage lesions often go undetected due to the subopti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd3393b6577f81af8447cf8a95ead3cc
https://pubmed.ncbi.nlm.nih.gov/16841334
https://pubmed.ncbi.nlm.nih.gov/16841334
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 41(7)
We have compared PC12 cell lines derived from different laboratories and the newly developed mouse pheochromocytoma (MPC) cell line. Morphologically, there were distinct differences in size, shape, adherence, and clumping behavior, which varied in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8ec24eec3d998a310d7f33d45dfb8e
https://pubmed.ncbi.nlm.nih.gov/16223334
https://pubmed.ncbi.nlm.nih.gov/16223334