Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Susanna Wu-Pong"'
Autor:
Ralph J. Altiere, Teresa W. Wilborn, James A. Karboski, Susanna Wu-Pong, Michael Manolakis, David R. Clark, Erin M. Timpe
Publikováno v:
Currents in Pharmacy Teaching and Learning. 5:9-13
Background Teaching workloads are often not clearly defined at academic institutions. Within health professional programs, the existence of both didactic and experiential teaching assignments make equitable distribution of teaching workloads more com
Publikováno v:
The FASEB Journal. 29
Autor:
Susanna Wu-Pong
Publikováno v:
Advanced Drug Delivery Reviews. 44:59-70
Elucidation of the mechanism of oligonucleotide (ON) cellular internalization has met an impasse at the lipid penetration stage. ON internalization is commonly regarded to involve endocytosis, yet the method by which the ON penetrates the endosome me
Publikováno v:
Journal of Addictive Diseases. 18:51-61
Traditionally, methadone maintenance therapy has been a once-daily dosing schedule. The current study evaluates the effectiveness of this regimen during pregnancy. A total of 23 pregnant and 16 non-pregnant opioid-dependent patients were studied in t
Publikováno v:
Biopharmaceutics & Drug Disposition. 20:411-416
Cellular and intestinal absorption of naked oligonucleotides (ONs) is limited and still remains a developmental challenge. A previous report in the literature suggests that ON absorption occurs via a paracellular mechanism. The aim of this study was
Autor:
Diana F. Thomas, Bharati Pai, Susanna Wu-Pong, Robert Tam, Josie Bard, Charmaine Lim, Amy Chan, Tatjana Milovanovic, Patrick J. Middleton
Publikováno v:
Antisense and Nucleic Acid Drug Development. 9:289-300
We previously showed that inhibition of the expression of CD28 (an essential immune receptor on T cells) mediated by a phosphorothioate (PS)-modified aptameric oligodeoxynucleotide (ODN) sequence, GR1, resulted in reduced T cell responses in vitro an
Autor:
Susanna Wu-Pong
Publikováno v:
IUBMB Life. 39:511-519
Oligodeoxynucleotides (ONs) are a powerful new class of drugs whose transport to the cytoplasm or nucleus inefficient and incompletely defined. Thus, to further extend our understanding of the mechanism of ON cellular uptake, the role of multivalent
Autor:
Peter R. Byron, Susanna Wu-Pong
Publikováno v:
Advanced Drug Delivery Reviews. 19:47-71
Because systemic delivery of proteins and peptides proceeds via the lung, and oligonucleotides (ONs) possess some similar molecular characteristics, it is tempting to propose that inhalation may solve some of the systemic delivery problems being expe
Autor:
Stephen J. Cutler, Yuen Sum, Vladimir P. Torchilin, William J. Jusko, Christine A. Sorkness, Milap C. Nahata, Robert A. Blouin, Rodney J. Y. Ho, Susanna Wu-Pong, M. Lynn Crismon, Diana I. Brixner
According to the Bylaws of the American Association of Colleges of Pharmacy (AACP), the Research and Graduate Affairs Committee (RGAC) shall provide assistance to the Association in developing its research, graduate education, and scholarship agenda.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df18a90cfd8b006504c5f9f01c4f3e6
Publikováno v:
Antisense Research and Development. 4:155-163
Previously described cell membrane transport mechanisms are unable to account completely for oligodeoxynucleotide cellular uptake. These charged macromolecules enter cells by an incompletely defined mechanism and downregulate gene expression in eithe