Výsledky vyhledávání - "Susanna Schraen‐Maschke"

Akademický článek

Clarifying the association of CSF Aβ, tau, BACE1, and neurogranin with AT(N) stages in Alzheimer disease

Autor: Sylvain Lehmann, Susanna Schraen-Maschke, Luc Buée, Jean-Sébastien Vidal, Constance Delaby, Christophe Hirtz, Frédéric Blanc, Claire Paquet, Bernadette Allinquant, Stéphanie Bombois, Audrey Gabelle, Olivier Hanon, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Publikováno v: Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-14 (2024)

Abstract Background Current AT(N) stratification for Alzheimer’s disease (AD) accounts for complex combinations of amyloid (A), tau proteinopathy (T) and neurodegeneration (N) signatures. Understanding the transition between these different stages

Externí odkaz: https://doaj.org/article/c860af25033746cb82e1ae7cdbcb2d80

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Akademický článek

Neurofilaments contribution in clinic: state of the art

Autor: Constance Delaby, Olivier Bousiges, Damien Bouvier, Catherine Fillée, Anthony Fourier, Etienne Mondésert, Nicolas Nezry, Souheil Omar, Isabelle Quadrio, Benoit Rucheton, Susanna Schraen-Maschke, Vincent van Pesch, Stéphanie Vicca, Sylvain Lehmann, Aurelie Bedel

Publikováno v: Frontiers in Aging Neuroscience, Vol 14 (2022)

Neurological biomarkers are particularly valuable to clinicians as they can be used for diagnosis, prognosis, or response to treatment. This field of neurology has evolved considerably in recent years with the improvement of analytical methods, allow

Externí odkaz: https://doaj.org/article/b931b35796fd4807bbef259aa2ce127f

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Plasma phosphorylated tau 181 predicts amyloid status and conversion to dementia stage dependent on renal function

Autor: Sylvain Lehmann, Susanna Schraen-Maschke, Jean-Sébastien Vidal, Constance Delaby, Frédéric Blanc, Claire Paquet, Bernadette Allinquant, Stéphanie Bombois, Audrey Gabelle, Olivier Hanon

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 94:411-419

ObjectivesPlasma P-tau181 is an increasingly established diagnostic marker for Alzheimer’s disease (AD). Further validation in prospective cohorts is still needed, as well as the study of confounding factors that could influence its blood level.Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d803ea983f64bba99eb7d36b356a49
https://doi.org/10.1136/jnnp-2022-330540

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Akademický článek

Somatostatin and Neuropeptide Y in Cerebrospinal Fluid: Correlations With Amyloid Peptides Aβ1–42 and Tau Proteins in Elderly Patients With Mild Cognitive Impairment

Autor: Emmanuelle Duron, Jean-Sébastien Vidal, Dominique Grousselle, Audrey Gabelle, Sylvain Lehmann, Florence Pasquier, Stéphanie Bombois, Luc Buée, Bernadette Allinquant, Susanna Schraen-Maschke, Christiane Baret, Anne-Sophie Rigaud, Olivier Hanon, Jacques Epelbaum

Publikováno v: Frontiers in Aging Neuroscience, Vol 10 (2018)

A combination of low cerebrospinal fluid (CSF) Amyloid β1–42 (Aβ1–42) and high Total-Tau (T-Tau) and Phosphorylated-Tau (P-Tau) occurs at a prodromal stage of Alzheimer’s disease (AD) and recent findings suggest that network abnormalities and

Externí odkaz: https://doaj.org/article/c2546e5c9f8a4a99a9fe2b92399fd965

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Neurofilaments: a key new biomarker for clinicians. Part 1: Importance of neurofilaments in the management of neurodegenerative diseases

Autor: Constance, Delaby, Olivier, Bousiges, Damien, Bouvier, Catherine, Fillée, Anthony, Fourier, Étienne, Mondésert, Nicolas, Nezry, Souheil, Omar, Isabelle, Quadrio, Benoit, Rucheton, Susanna, Schraen-Maschke, Vincent, van Pesch, Stéphanie, Vicca, Sylvain, Lehmann, Aurélie, Bedel

Publikováno v: Annales de biologie clinique. 80(5)

Neurological biomarkers are of great use for clinicians, as they can be used for numerous purposes: guiding clinical diagnosis, estimating prognosis, assessing disease stage and monitoring progression or response to treatment. This field of neurology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ccbd24c17194f2b49bc73ec0081cfdaa
https://pubmed.ncbi.nlm.nih.gov/36453742

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Neurofilaments: a key new biomarker for clinicians. Part 2: Neurofilaments, an asset beyond neurodegenerative diseases

Publikováno v: Annales de biologie clinique. 80(5)

Neurofilaments (Nf) are proteins selectively expressed in the cytoskeleton of neurons, and their increase is a marker of neuronal damage. The potential utility of neurofilament light chain (NfL) has recently increased considerably, well beyond neurod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38ee973863ee68c1d0b3e85385d29c5f
https://pubmed.ncbi.nlm.nih.gov/36453743

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Akademický článek

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology

Publikováno v: Neurobiology of Disease, Vol 43, Iss 2, Pp 486-494 (2011)

Tau pathology is encountered in many neurodegenerative disorders known as tauopathies, including Alzheimer's disease. Physical activity is a lifestyle factor affecting processes crucial for memory and synaptic plasticity. Whether long-term voluntary

Externí odkaz: https://doaj.org/article/474624de82d042e7851d6576a260bf6a

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