Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Susanna S.T. Lee"'
Autor:
Susanna S.T. Lee, Wood-Yee Chan, Cherry K.C. Lo, David C.C. Wan, David S.C. Tsang, Wing-Tai Cheung
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 11, Pp 2025-2037 (2004)
The peroxisome proliferator-activated receptor α (PPARα) has been implicated as a key control of fatty acid catabolism during the cellular fasting. However, little is known regarding changes of individual fatty acids in hepatic triacylglycerol (TG)
Externí odkaz:
https://doaj.org/article/ba4d37311d7a4722b60ade3f60fbb3df
Autor:
Xing Liu, Jian Xu, Susanna S.T. Lee, Kai Wang, Pik-Shan Li, Wing-Tai Cheung, Angus Y. Lee, Martin Yan-Chun Chan
Publikováno v:
Transgenic research. 29(5-6)
SULT2A8 is a male-predominant and liver-specific mouse cytosolic sulfotransferase (SULT) that sulfonates 7α-hydroxyl (7α-OH) bile acids in vitro. Sulfonation regulates bile acid homeostasis, which in turn regulates cholesterol and energy metabolism
Autor:
Elaine Y.M. Chan, Ying Shi, Lili Jin, Naiming Zhou, Qiang Ma, Chun Chu, Wing-Tai Cheung, Meina Sun, Zhou-Fang Li, Ka Fai To, Susanna S.T. Lee, Da-Kui Wang, Li Zhang, Helen Wise, Wei Qi
Publikováno v:
Cytokine. 102:62-75
Previously our lab has created a mouse ovarian xenograft model of copy number variation (CNV)-mediated G protein-coupled receptor (GPCR) MAS-driven tumorigenesis, and RNA profiling identified a putative chemokine tumor-induced factor (Tif). Sequence
Autor:
Xing Liu, Jian Xu, Yee-Lok Yuen, Lu Feng, Kai Wang, Susanna S.T. Lee, Wing-Tai Cheung, Wing-Ping Fong, Martin Yan-Chun Chan
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1114-1131 (2017)
PPARα has been known to play a pivotal role in orchestrating lipid, glucose, and amino acid metabolism via transcriptional regulation of its target gene expression during energy deprivation. Recent evidence has also suggested that PPARα is involved
Autor:
Susanna S.T. Lee, Wing-Tai Cheung, Lu Feng, Kai Wang, Xing Liu, Yan-Chun Chan, Shannon Wing-Ngor Au, Pui-Kin So
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100074-(2021)
Journal of Lipid Research
Journal of Lipid Research
Cytosolic sulfotransferases (SULTs) catalyze the transfer of a sulfonate group from the cofactor 3’-phosphoadenosine 5’-phosphosulfate to a hydroxyl (OH) containing substrate and play a critical role in the homeostasis of endogenous compounds, in
Publikováno v:
Protein Expression and Purification. 68:190-195
Millions of candidate clones are commonly obtained following rounds of phage-displayed antibody library panning, and expression of those selected single-chain variable fragment (scFv) is required for secondary functional screening to identify positiv
Publikováno v:
Biologicals. 37:277-281
DHFR-deficient Chinese hamster ovary (CHO DHFR(-)) cells are the most popular mammalian expression system for inducible amplification of transgene. In order to obtain more stable transfected CHO DHFR(-) cell clones, transfection efficiency of electro
Autor:
Sup-Yin Tsang, Wood Yee Chan, Wen-Zhen Lin, Lydia K.W. Lung, You-Kai Zhu, Zhou-Fang Li, Wing-Tai Cheung, Da-Kui Wang, Susanna S.T. Lee
Publikováno v:
International Journal of Cancer. 125:1316-1327
Overexpressions of G protein-coupled receptor (GPCR) with elevated downstream signaling events have been reported in various tumors. However, the cellular mechanism that GPCR overexpression leads to tumor formation is largely unknown. The orphan GPCR
Publikováno v:
European Journal of Pharmacology. 557:204-211
Angiotensin and endothelin are vasoactive peptides with neuromodulatory effect, however their interactions in facilitating neurotransmission are largely unknown. In the present study, effort was made to examine how endothelin 1 modulates angiotensin
Autor:
Man Cheng, Qi Zhao, Rama Kamesh Bikkavilli, Randy Chi Fai Cheung, Ceci W.L. Chan, Shannon Wing-Ngor Au, Walter K.K. Ho, Paul K.S. Chan, Susanna S.T. Lee, Gregory Cheng, Wing-Tai Cheung
Publikováno v:
Biochemical and Biophysical Research Communications
Infection of SARS-associated coronavirus (SARS-CoV) induced a strong anti-nucleocapsid (anti-N) antibody response. However, the pathophysiological significance of the anti-N antibodies in SARS pathogenesis is largely unknown. To profile the anti-N an