Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Susanna R. Bidgood"'
Autor:
Efstathios S. Giotis, Stephen M. Laidlaw, Susanna R. Bidgood, David Albrecht, Jemima J. Burden, Rebecca C. Robey, Jason Mercer, Michael A. Skinner
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 634 (2020)
The avian pathogen fowlpox virus (FWPV) has been successfully used as a vaccine vector in poultry and humans, but relatively little is known about its ability to modulate host antiviral immune responses in these hosts, which are replication-permissiv
Externí odkaz:
https://doaj.org/article/bcd2342d2df34c9faf16cfb083aaf866
Autor:
Susanna R. Bidgood, Jason Mercer
Publikováno v:
Viruses, Vol 7, Iss 8, Pp 4800-4825 (2015)
As all viruses rely on cellular factors throughout their replication cycle, to be successful they must evolve strategies to evade and/or manipulate the defence mechanisms employed by the host cell. In addition to their expression of a wide array of h
Externí odkaz:
https://doaj.org/article/70eb8895bb614c6486d4727e58358175
Autor:
Karel Novy, David Albrecht, Abigail Collopy, Jason Mercer, Melanie Krause, Jemima J. Burden, Susanna R. Bidgood, Bernd Wollscheid
Publikováno v:
PLoS Pathogens, 18 (7)
All poxviruses contain a set of proteinaceous structures termed lateral bodies (LB) that deliver viral effector proteins into the host cytosol during virus entry. To date, the spatial proteotype of LBs remains unknown. Using the prototypic poxvirus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cae8485978ab238fc5b748f9ac0402
https://pubmed.ncbi.nlm.nih.gov/35834477
https://pubmed.ncbi.nlm.nih.gov/35834477
Autor:
Victoria Gould, Josua Oderbolz, Roman Spörri, Vural Yilmaz, Annette Oxenius, Jason Mercer, Susanna R. Bidgood, Suzanne P. M. Welten
Publikováno v:
Mucosal Immunology
Mucosal Immunology, 14 (3)
Mucosal Immunology, 14 (3)
Induction of memory CD8 T cells residing in peripheral tissues is of interest for T cell-based vaccines as these cells are located at mucosal and barrier sites and can immediately exert effector functions, thus providing protection in case of local p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9d7eea94b8a801636faba12753bc6e
Autor:
Jemima J. Burden, David Albrecht, Michael A. Skinner, Efstathios S. Giotis, Rebecca C. Robey, Stephen M. Laidlaw, Jason Mercer, Susanna R. Bidgood
Publikováno v:
Biomedicines, Vol 8, Iss 634, p 634 (2020)
Biomedicines
Volume 8
Issue 12
Biomedicines
Volume 8
Issue 12
The avian pathogen fowlpox virus (FWPV) has been successfully used as a vaccine vector in poultry and humans, but relatively little is known about its ability to modulate host antiviral immune responses in these hosts, which are replication-permissiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ea0953196337a55993d9a5b286cb86
https://www.mdpi.com/2227-9059/8/12/634
https://www.mdpi.com/2227-9059/8/12/634
Autor:
Jason Mercer, Jemima J. Burden, Stephen M. Laidlaw, Michael A. Skinner, Efstathios S. Giotis, David Albrecht, Rebecca C. Robey, Susanna R. Bidgood
The avian pathogen, fowlpox virus (FWPV) has been successfully used as vaccine vector in poultry and humans but relatively little is known about its ability to modulate host antiviral immune responses in these hosts, which are replication permissive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b5ba65224cb1874d6357e08633fae79
https://doi.org/10.1101/2020.10.02.324418
https://doi.org/10.1101/2020.10.02.324418
Autor:
Jason Mercer, Susanna R. Bidgood
Publikováno v:
Viruses
Viruses, Vol 7, Iss 8, Pp 4800-4825 (2015)
Viruses, Vol 7, Iss 8, Pp 4800-4825 (2015)
As all viruses rely on cellular factors throughout their replication cycle, to be successful they must evolve strategies to evade and/or manipulate the defence mechanisms employed by the host cell. In addition to their expression of a wide array of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81171a5c021754af0caf1da9198d6efd
https://doi.org/10.3390/v7082844
https://doi.org/10.3390/v7082844
Autor:
Jerry C. H. Tam, Leo C. James, William A. McEwan, Donna L. Mallery, Susanna R. Bidgood, Ruth E. Watkinson
Publikováno v:
Nature Immunology. 14:327-336
During pathogen infection, antibodies can be carried into the infected cell, where they are detected by the ubiquitously expressed cytosolic antibody receptor TRIM21. Here we found that recognition of intracellular antibodies by TRIM21 activated immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6246e802c91e43424820e473c10883e
https://doi.org/10.1038/ni.2548
https://doi.org/10.1038/ni.2548
Publikováno v:
Proceedings of the National Academy of Sciences
Tripartite motif-containing 21 (TRIM21) is a cytosolic IgG receptor that mediates intracellular virus neutralization by antibody. TRIM21 targets virions for destruction in the proteasome, but it is unclear how a substrate as large as a viral capsid i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388f1d6f3831d7ab6c03d7e5dc4de230
https://doi.org/10.1073/pnas.1210659109
https://doi.org/10.1073/pnas.1210659109
Publikováno v:
Science. 345
Bringing in the agent of your own destruction Cells need mechanisms to detect and disable pathogens that infect them. Tam et al. now show that complement C3, a protein that binds to pathogens in the blood, can enter target cells together with the pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8ec54d8c0ebc1d5dec0a0fa9ceedbf
https://doi.org/10.1126/science.1256070
https://doi.org/10.1126/science.1256070