Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Susanna R Bidgood"'
Autor:
Susanna R Bidgood, Jerzy Samolej, Karel Novy, Abigail Collopy, David Albrecht, Melanie Krause, Jemima J Burden, Bernd Wollscheid, Jason Mercer
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010614 (2022)
All poxviruses contain a set of proteinaceous structures termed lateral bodies (LB) that deliver viral effector proteins into the host cytosol during virus entry. To date, the spatial proteotype of LBs remains unknown. Using the prototypic poxvirus,
Externí odkaz:
https://doaj.org/article/d3a0110eda7146bcbc882c71dcde7494
Autor:
Susanna R Bidgood
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e3000124 (2019)
The eradication of smallpox is one of the greatest medical successes in history. Vaccinia virus was made famous by being the virus used in the live vaccine that enabled this feat. Nearly 40 years on from that success, this prototypical poxvirus conti
Externí odkaz:
https://doaj.org/article/373d5adcc2db4457bbef08d073bfa9cd
Autor:
Susanna R. Bidgood, Jason Mercer
Publikováno v:
Viruses, Vol 7, Iss 8, Pp 4800-4825 (2015)
As all viruses rely on cellular factors throughout their replication cycle, to be successful they must evolve strategies to evade and/or manipulate the defence mechanisms employed by the host cell. In addition to their expression of a wide array of h
Externí odkaz:
https://doaj.org/article/70eb8895bb614c6486d4727e58358175
Autor:
Karel Novy, David Albrecht, Abigail Collopy, Jason Mercer, Melanie Krause, Jemima J. Burden, Susanna R. Bidgood, Bernd Wollscheid
Publikováno v:
PLoS Pathogens, 18 (7)
All poxviruses contain a set of proteinaceous structures termed lateral bodies (LB) that deliver viral effector proteins into the host cytosol during virus entry. To date, the spatial proteotype of LBs remains unknown. Using the prototypic poxvirus,
Autor:
Victoria Gould, Josua Oderbolz, Roman Spörri, Vural Yilmaz, Annette Oxenius, Jason Mercer, Susanna R. Bidgood, Suzanne P. M. Welten
Publikováno v:
Mucosal Immunology
Mucosal Immunology, 14 (3)
Mucosal Immunology, 14 (3)
Induction of memory CD8 T cells residing in peripheral tissues is of interest for T cell-based vaccines as these cells are located at mucosal and barrier sites and can immediately exert effector functions, thus providing protection in case of local p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9d7eea94b8a801636faba12753bc6e
Autor:
Jemima J. Burden, David Albrecht, Michael A. Skinner, Efstathios S. Giotis, Rebecca C. Robey, Stephen M. Laidlaw, Jason Mercer, Susanna R. Bidgood
Publikováno v:
Biomedicines, Vol 8, Iss 634, p 634 (2020)
Biomedicines
Volume 8
Issue 12
Biomedicines
Volume 8
Issue 12
The avian pathogen fowlpox virus (FWPV) has been successfully used as a vaccine vector in poultry and humans, but relatively little is known about its ability to modulate host antiviral immune responses in these hosts, which are replication-permissiv
Autor:
Jason Mercer, Jemima J. Burden, Stephen M. Laidlaw, Michael A. Skinner, Efstathios S. Giotis, David Albrecht, Rebecca C. Robey, Susanna R. Bidgood
The avian pathogen, fowlpox virus (FWPV) has been successfully used as vaccine vector in poultry and humans but relatively little is known about its ability to modulate host antiviral immune responses in these hosts, which are replication permissive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b5ba65224cb1874d6357e08633fae79
https://doi.org/10.1101/2020.10.02.324418
https://doi.org/10.1101/2020.10.02.324418
Autor:
Jason Mercer, Susanna R. Bidgood
Publikováno v:
Viruses
Viruses, Vol 7, Iss 8, Pp 4800-4825 (2015)
Viruses, Vol 7, Iss 8, Pp 4800-4825 (2015)
As all viruses rely on cellular factors throughout their replication cycle, to be successful they must evolve strategies to evade and/or manipulate the defence mechanisms employed by the host cell. In addition to their expression of a wide array of h
Autor:
Jerry C. H. Tam, Leo C. James, William A. McEwan, Donna L. Mallery, Susanna R. Bidgood, Ruth E. Watkinson
Publikováno v:
Nature Immunology. 14:327-336
During pathogen infection, antibodies can be carried into the infected cell, where they are detected by the ubiquitously expressed cytosolic antibody receptor TRIM21. Here we found that recognition of intracellular antibodies by TRIM21 activated immu
Publikováno v:
Proceedings of the National Academy of Sciences
Tripartite motif-containing 21 (TRIM21) is a cytosolic IgG receptor that mediates intracellular virus neutralization by antibody. TRIM21 targets virions for destruction in the proteasome, but it is unclear how a substrate as large as a viral capsid i