Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Susanna Mantovani"'
Autor:
Marina Picca, Paola Manzoni, Gregorio Paolo Milani, Susanna Mantovani, Claudio Cravidi, Danila Mariani, Angela Mezzopane, Roberto Marinello, Chiara Bove, Paolo Ferri, Marina Macchi, Carlo Agostoni
Publikováno v:
Italian Journal of Pediatrics, Vol 47, Iss 1, Pp 1-6 (2021)
Abstract Background The COVID-19 pandemic and the subsequent national lockdowns, school closures and distance learning may have had both negative and positive effects on physical and mental health of children. Methods A cross-sectional study was cond
Externí odkaz:
https://doaj.org/article/764edc2805bc41e5890950bb63b99cf3
Autor:
Ihssane Bouybayoune, Susanna Mantovani, Federico Del Gallo, Ilaria Bertani, Elena Restelli, Liliana Comerio, Laura Tapella, Francesca Baracchi, Natalia Fernández-Borges, Michela Mangieri, Cinzia Bisighini, Galina V Beznoussenko, Alessandra Paladini, Claudia Balducci, Edoardo Micotti, Gianluigi Forloni, Joaquín Castilla, Fabio Fiordaliso, Fabrizio Tagliavini, Luca Imeri, Roberto Chiesa
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004796 (2015)
Fatal familial insomnia (FFI) and a genetic form of Creutzfeldt-Jakob disease (CJD178) are clinically different prion disorders linked to the D178N prion protein (PrP) mutation. The disease phenotype is determined by the 129 M/V polymorphism on the m
Externí odkaz:
https://doaj.org/article/e39e868d112f4eefbd99d99067a3fcfe
Autor:
Elena Restelli, Luana Fioriti, Susanna Mantovani, Simona Airaghi, Gianluigi Forloni, Roberto Chiesa
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13725 (2010)
A key pathogenic role in prion diseases was proposed for a cytosolic form of the prion protein (PrP). However, it is not clear how cytosolic PrP localization influences neuronal viability, with either cytotoxic or anti-apoptotic effects reported in d
Externí odkaz:
https://doaj.org/article/10a4615873e94b839db12ab7ad52a19c
Autor:
Emiliano Biasini, Laura Tapella, Susanna Mantovani, Matteo Stravalaci, Marco Gobbi, David A Harris, Roberto Chiesa
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7816 (2009)
BACKGROUND:Prion diseases are fatal neurodegenerative disorders that can arise sporadically, be genetically inherited or acquired through infection. The key event in these diseases is misfolding of the cellular prion protein (PrP(C)) into a pathogeni
Externí odkaz:
https://doaj.org/article/785873e47a51404e9239c532e09584d3
Publikováno v:
Molecular Immunology. 68:253-260
The innate immune system is the first line of defence against pathogens and infection. Recently, it has become apparent that many innate immune factors have roles outside of immunity and there is growing evidence that these factors play important fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e26c98f93cc8efb0e2ab3013ef74316
https://doi.org/10.1016/j.molimm.2015.09.004
https://doi.org/10.1016/j.molimm.2015.09.004
Autor:
Avril A. B. Robertson, Dominic B. Rowe, Mark E. Cooper, Richard D. Gordon, Daniel C. Christie, Vinod Kumar, Luke A. J. O'Neill, Kate Schroder, Monica R. Langley, Eduardo A. Albornoz, Susanna Mantovani, Anumantha G. Kanthasamy, Mark S. Butler, Trent M. Woodruff
Publikováno v:
Science Translational Medicine. 10
Parkinson’s disease (PD) is characterized by a profound loss of dopaminergic neurons in the substantia nigra, accompanied by chronic neuroinflammation, mitochondrial dysfunction, and widespread accumulation of α-synuclein-rich protein aggregates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b854df622326c2a6cdf5ebc79dc71e
https://doi.org/10.1126/scitranslmed.aah4066
https://doi.org/10.1126/scitranslmed.aah4066
Autor:
Frederik J. Steyn, Trent M. Woodruff, John D. O'Sullivan, Lili Huang, Shyuan T. Ngo, Susanna Mantovani, Robert D. Henderson, Casey M. M. Pfluger, Pamela A. McCombe
Publikováno v:
Journal of the Neurological Sciences. 357:22-27
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the loss of upper cortical and lower motor neurons. ALS causes death within 2–5years of diagnosis. Diet and body mass index influence the clinical cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36355e30b6347ee57c615c3e0e8fe71f
https://doi.org/10.1016/j.jns.2015.06.053
https://doi.org/10.1016/j.jns.2015.06.053
Publikováno v:
Seminars in immunology. 37
From its discovery in the late nineteenth century, as a 'complement' to the cellular immune response, the complement system has been widely affirmed as a powerful controller of innate and adaptive immune responses. In recent decades however, new role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3916e1b3a20230167a3e4e8cd70478e5
https://pubmed.ncbi.nlm.nih.gov/29525104
https://pubmed.ncbi.nlm.nih.gov/29525104
Publikováno v:
Journal of sleep research. 27(3)
Sleep and circadian alterations are amongst the very first symptoms experienced in Parkinson's disease, and sleep alterations are present in the majority of patients with overt clinical manifestation of Parkinson's disease. However, the magnitude of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e462d98a1ebbebfb0dc58a985f2afcab
https://pubmed.ncbi.nlm.nih.gov/29493044
https://pubmed.ncbi.nlm.nih.gov/29493044