Zobrazeno 1 - 10
of 883
pro vyhledávání: '"Susanna J"'
Autor:
Tran Tan Thanh, Nguyen Thi Kha Tu, Lam Anh Nguyet, Cao Thu Thuy, Nguyen Lam Thai Thuan, Nguyen Thi Han Ny, Le Nguyen Truc Nhu, Le Kim Thanh, Nguyen Thi Thu Hong, Nguyen To Anh, Nguyen Thanh Truong, Nguyen Van Vinh Chau, Lam Minh Yen, Phan Van E, Nguyen Phong Thuong, Nguyen Van Truc, Pham Huu Trung, Wee Chee Yap, Rahul Pandey, Sidney Yee, Ruifen Weng, Juthathip Mongkolsapaya, Wanwisa Dejnirattisai, Raph L Hamers, Narisara Chantratita, Gavin Screaton, Susanna J Dunachie, E Yvonne Jones, David I Stuart, Nguyen Thanh Dung, Guy Thwaites, Lin-Fa Wang, Chee Wah Tan, Le Van Tan
Publikováno v:
International Journal of Infectious Diseases, Vol 147, Iss , Pp 107173- (2024)
Objectives: We studied the immunogenicity after primary and booster vaccinations of the Abdala COVID-19 vaccine, a receptor-binding domain protein subunit vaccine, in Vietnamese people by determining the level of neutralization and cross-neutralizati
Externí odkaz:
https://doaj.org/article/9a8af1cae72c4399a2eb6c5de3594acc
Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection
Autor:
Chang Liu, Raksha Das, Aiste Dijokaite-Guraliuc, Daming Zhou, Alexander J. Mentzer, Piyada Supasa, Muneeswaran Selvaraj, Helen M. E. Duyvesteyn, Thomas G. Ritter, Nigel Temperton, Paul Klenerman, Susanna J. Dunachie, Neil G. Paterson, Mark A. Williams, David R. Hall, Elizabeth E. Fry, Juthathip Mongkolsapaya, Jingshan Ren, David I. Stuart, Gavin R. Screaton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The rapid evolution of SARS-CoV-2 is driven in part by a need to evade the antibody response in the face of high levels of immunity. Here, we isolate spike (S) binding monoclonal antibodies (mAbs) from vaccinees who suffered vaccine break-th
Externí odkaz:
https://doaj.org/article/cc28ab08066f4f34ade2b16555c78a91
Autor:
Daming Zhou, Piyada Supasa, Chang Liu, Aiste Dijokaite-Guraliuc, Helen M. E. Duyvesteyn, Muneeswaran Selvaraj, Alexander J. Mentzer, Raksha Das, Wanwisa Dejnirattisai, Nigel Temperton, Paul Klenerman, Susanna J. Dunachie, Elizabeth E. Fry, Juthathip Mongkolsapaya, Jingshan Ren, David I. Stuart, Gavin R. Screaton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Under pressure from neutralising antibodies induced by vaccination or infection the SARS-CoV-2 spike gene has become a hotspot for evolutionary change, leading to the failure of all mAbs developed for clinical use. Most potent antibodies bin
Externí odkaz:
https://doaj.org/article/40347f991a6543e8a3b3edb8d9a26a4b
Autor:
Susanna J. Sabin, Cari A. Beesley, Chung K. Marston, Taylor K. Paisie, Christopher A. Gulvik, Gregory A. Sprenger, Jay E. Gee, Rita M. Traxler, Melissa E. Bell, John R. McQuiston, Zachary P. Weiner
Publikováno v:
Pathogens, Vol 13, Iss 10, p 884 (2024)
Bacillus anthracis causes anthrax through virulence factors encoded on two plasmids. However, non-B. anthracis organisms within the closely related, environmentally ubiquitous Bacillus cereus group (BCG) may cause an anthrax-like disease in humans th
Externí odkaz:
https://doaj.org/article/2d144d4321974dd9ae71b2567eb0c28d
Autor:
Susanna J. Dunachie, Raph L. Hamers, Alba Grifoni, Narisara Chantratita, Juthathip Mongkolsapaya, E. Yvonne Jones, Vu Duy Thanh, David I. Stuart, Alessandro Sette, Lin-Fa Wang, Chee Wah Tan, Paul Klenerman, Le Van Tan, Guy Thwaites, Phaik Yeong Cheah, Jennifer Hill, Gavin Screaton, Mary Chambers, Le Nguyen Truc Nhu, Wanwisa Dejnirattisai, Nicholas P.J. Day
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
A strong and effective COVID-19 and future pandemic responses rely on global efforts to carry out surveillance of infections and emerging SARS-CoV-2 variants and to act accordingly in real time. Many countries in Southeast Asia lack capacity to deter
Externí odkaz:
https://doaj.org/article/9a2e701c50c2420092f60612a6d2672f
Autor:
Hailey Hornsby, Alexander R. Nicols, Stephanie Longet, Chang Liu, Adriana Tomic, Adrienn Angyal, Barbara Kronsteiner, Jessica K. Tyerman, Tom Tipton, Peijun Zhang, Marta Gallis, Piyada Supasa, Muneeswaran Selvaraj, Priyanka Abraham, Isabel Neale, Mohammad Ali, Natalie A. Barratt, Jeremy M. Nell, Lotta Gustafsson, Scarlett Strickland, Irina Grouneva, Timothy Rostron, Shona C. Moore, Luisa M. Hering, Susan L. Dobson, Sagida Bibi, Juthathip Mongkolsapaya, Teresa Lambe, Dan Wootton, Victoria Hall, Susan Hopkins, Tao Dong, Eleanor Barnes, Gavin Screaton, The PITCH Consortium, Alex Richter, Lance Turtle, Sarah L. Rowland-Jones, Miles Carroll, Christopher J. A. Duncan, Paul Klenerman, Susanna J. Dunachie, Rebecca P. Payne, Thushan I. de Silva
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Pronounced immune escape by the SARS-CoV-2 Omicron variant has resulted in many individuals possessing hybrid immunity, generated through a combination of vaccination and infection. Concerns have been raised that omicron breakthrough infecti
Externí odkaz:
https://doaj.org/article/b703690a29154c058004a652610402dd
Autor:
Liam Smeeth, Nish Chaturvedi, Carol Brayne, Rohini Mathur, Krishnan Bhaskaran, Rutendo Muzambi, Charlotte Warren-Gash, Christopher T Rentsch, Dylan M Williams, Susanna J Dunachie, William Doran, Louis Tunnicliffe, Sophie V Eastwood
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 1 (2024)
Introduction 4.2 million individuals in the UK have type 2 diabetes, a known risk factor for dementia and mild cognitive impairment (MCI). Diabetes treatment may modify this association, but existing evidence is conflicting. We therefore aimed to ass
Externí odkaz:
https://doaj.org/article/b4a13d0b549447b1a40d1b3a83e8a4c8
Autor:
Manon Ragonnet-Cronin, Rungtiwa Nutalai, Jiandong Huo, Aiste Dijokaite-Guraliuc, Raksha Das, Aekkachai Tuekprakhon, Piyada Supasa, Chang Liu, Muneeswaran Selvaraj, Natalie Groves, Hassan Hartman, Nicholas Ellaby, J. Mark Sutton, Mohammad W. Bahar, Daming Zhou, Elizabeth Fry, Jingshan Ren, Colin Brown, Paul Klenerman, Susanna J. Dunachie, Juthathip Mongkolsapaya, Susan Hopkins, Meera Chand, David I. Stuart, Gavin R. Screaton, Sakib Rokadiya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract COVID-19 patients at risk of severe disease may be treated with neutralising monoclonal antibodies (mAbs). To minimise virus escape from neutralisation these are administered as combinations e.g. casirivimab+imdevimab or, for antibodies targ
Externí odkaz:
https://doaj.org/article/3441fa6cd88c4fceaa3ef6f2d837af24
Autor:
Helen Ratcliffe, Karen S. Tiley, Stephanie Longet, Claire Tonry, Cathal Roarty, Chris Watson, Gayatri Amirthalingam, Iason Vichos, Ella Morey, Naomi L. Douglas, Spyridoula Marinou, Emma Plested, Parvinder K. Aley, Eva Galiza, Saul N. Faust, Stephen Hughes, Clare Murray, Marion R. Roderick, Fiona Shackley, Sam Oddie, Tim W.R. Lee, David P.J. Turner, Mala Raman, Stephen Owens, Paul J. Turner, Helen Cockerill, Jamie Lopez Bernal, Samreen Ijaz, John Poh, Justin Shute, Ezra Linley, Ray Borrow, Katja Hoschler, Kevin E. Brown, Miles W. Carroll, Paul Klenerman, Susanna J. Dunachie, Mary Ramsay, Merryn Voysey, Thomas Waterfield, Matthew D. Snape
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108500- (2023)
Summary: SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalization. Why this is so remains unclear. Here we explore the potential for protection due to pre-existing cross-reactive s
Externí odkaz:
https://doaj.org/article/d001144b1e95484bbbfeb1677546d166
Autor:
Gabriel E. Wagner, Thomas Franz Paul Stanjek, Dirk Albrecht, Michaela Lipp, Susanna J. Dunachie, Esther Föderl-Höbenreich, Katharina Riedel, Anne Kohler, Ivo Steinmetz, Christian Kohler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe environmental bacterium Burkholderia pseudomallei causes the often fatal and massively underreported infectious disease melioidosis. Antigens inducing protective immunity in experimental models have recently been identified and serodi
Externí odkaz:
https://doaj.org/article/26cabcceb2f4435a9802762527a53d01