Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Susanna Gräfe"'
Autor:
Katharina Achazi, Michael H. Staegemann, Burkhard Gitter, Susanna Gräfe, Elisa Quaas, Rainer Haag, Arno Wiehe
Publikováno v:
Biomacromolecules. 19:222-238
An adaptable approach toward cleavable nanoparticle carrier systems for photodynamic therapy (PDT) is presented, comprising a biocompatible carrier loaded with multiple photosensitizer (PS) molecules related to the clinically employed PS Temoporfin,
Autor:
Daniela Meier, Susanna Gräfe, Sander M. Botter, Bernhard Robl, Walter Born, Bruno Fuchs, Giovanni Pellegrini, Carmen Campanile
Publikováno v:
International Journal of Cancer. 140:1680-1692
Current osteosarcoma therapies cause severe treatment-related side effects and chemoresistance, and have low success rates. Consequently, alternative treatment options are urgently needed. Photodynamic therapy (PDT) is a minimally invasive, local the
Autor:
Ilya Yakavets, Lina Bezdetnaya, Henri-Pierre Lassalle, Vladimir Zorin, Igor Yankovsky, Susanna Gräfe, Estelle Bastien, Ivan I. Khludeyev
Publikováno v:
European Journal of Pharmaceutical Sciences
European Journal of Pharmaceutical Sciences, Elsevier, 2016, 91, pp.172-182. ⟨10.1016/j.ejps.2016.06.012⟩
European Journal of Pharmaceutical Sciences, Elsevier, 2016, 91, pp.172-182. ⟨10.1016/j.ejps.2016.06.012⟩
International audience; Application ofmeta-tetra(hydroxyphenyl)chorin (mTHPC) one of themost effective photosensitizer (PS) in photodynamic therapy of solid tumors encounters several complications resulting from its insolubility in aqueous medium. To
Autor:
Rudolf W. Steiner, Ralf-Uwe Peter, Arno Wiehe, Zhenxin Zhu, Rainer Wittig, Anastasia V. Ryabova, Claudia Scalfi-Happ, Victor B. Loschenov, Susanna Gräfe
Publikováno v:
Journal of photochemistry and photobiology. B, Biology. 185
The monocyte/macrophage cell lineage reveals an enormous plasticity, which is required for tissue homeostasis, but is also undermined in various disease states, leading to a functional involvement of macrophages in major human diseases such as athero
Autor:
Susanna Gräfe, Katarina Svanberg, Haiyan Xie, Stefan Andersson-Engels, Maria Kyriazi, Pontus Svenmarker, Niels Bendsoe, Johan Axelsson
Publikováno v:
Journal of Biophotonics. 8:142-152
in Undetermined Fospeg® is a newly developed photosensitizer formulation based on meso-tetra(hydroxyphenyl)chlorin (mTHPC), with hydrophilic liposomes to carry the hydrophobic photosensitizer to the target tissue. In this study the pharmacokinetics
Autor:
Susanna Gräfe, Fabrice Navarro, Doris Hinger, Devaraj Pandiarajan, Anne-Claude Couffin, Bernhard Spingler, Caroline Maake, Heinrich Walt
Publikováno v:
Journal of Nanobiotechnology
J Nanobiotechnology
J Nanobiotechnology
Background Photodynamic therapy (PDT) as promising alternative to conventional cancer treatments works by irradiation of a photosensitizer (PS) with light, which creates reactive oxygen species and singlet oxygen (1O2), that damage the tumor. However
Autor:
Daniela, Meier, Sander M, Botter, Carmen, Campanile, Bernhard, Robl, Susanna, Gräfe, Giovanni, Pellegrini, Walter, Born, Bruno, Fuchs
Publikováno v:
International journal of cancer. 140(7)
Current osteosarcoma therapies cause severe treatment-related side effects and chemoresistance, and have low success rates. Consequently, alternative treatment options are urgently needed. Photodynamic therapy (PDT) is a minimally invasive, local the
Autor:
Keith J. Flanagan, Arno Wiehe, Claudia S. Gutsche, Mathias O. Senge, Nora Kulak, Susanna Gräfe, Marlene Ortwerth, Hans-Ulrich Reissig
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 22(39)
The application of porphyrinoids in biomedical fields, such as photodynamic therapy (PDT), requires the introduction of functional groups to tune their solubility for the biological environment and to allow a coupling to other active moieties or carr
Autor:
Julie Garrier, Marie Ange d'Hallewin, François Guillemin, Lina Bezdetnaya, Susanna Gräfe, Catherine Barlier
Publikováno v:
Photodiagnosis and Photodynamic Therapy
Photodiagnosis and Photodynamic Therapy, Elsevier, 2011, 8 (4), pp.321-327. ⟨10.1016/j.pdpdt.2011.06.003⟩
Photodiagnosis and Photodynamic Therapy, Elsevier, 2011, 8 (4), pp.321-327. ⟨10.1016/j.pdpdt.2011.06.003⟩
International audience; Abstract: Background. Collagen matrices as substitution for connective tissue are known to promote wound healing. Photodynamic therapy has been anecdotally associated with improved wound healing and reduced scarring. The prese
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 91:41-50
Temoporfin (mTHPC) represents a very potent second-generation synthetic photosensitizer. It has shown to be effective in the photodynamic therapy of early or recurrent oral carcinomas, in the palliative treatment of refractory oral carcinomas and in