Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Susann M. Brady‐Kalnay"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4274 (2023)
PTPmu (PTPµ) is a member of the receptor protein tyrosine phosphatase IIb family that participates in cell-cell adhesion and signaling. PTPmu is proteolytically downregulated in glioblastoma (glioma), and the resulting extracellular and intracellula
Externí odkaz:
https://doaj.org/article/5e0c458d47eb476eb8c947d6f0f6061d
Autor:
Christian E. Anderson, Shannon B. Donnola, Yun Jiang, Joshua Batesole, Rebecca Darrah, Mitchell L. Drumm, Susann M. Brady-Kalnay, Nicole F. Steinmetz, Xin Yu, Mark A. Griswold, Chris A. Flask
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Injectable Magnetic Resonance Imaging (MRI) contrast agents have been widely used to provide critical assessments of disease for both clinical and basic science imaging research studies. The scope of available MRI contrast agents has expande
Externí odkaz:
https://doaj.org/article/4a950a2595b44f11a9e01dfa43686cfc
Autor:
Mette L. Johansen, Reshani Perera, Eric Abenojar, Xinning Wang, Jason Vincent, Agata A. Exner, Susann M. Brady-Kalnay
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1983 (2021)
Ultrasound imaging is a widely used, readily accessible and safe imaging modality. Molecularly-targeted microbubble- and nanobubble-based contrast agents used in conjunction with ultrasound imaging expand the utility of this modality by specifically
Externí odkaz:
https://doaj.org/article/60604975e48a4c21be6846168c1bfd52
Autor:
Jason Vincent, Sonya E. L. Craig, Mette L. Johansen, Jyosthna Narla, Stefanie Avril, Analisa DiFeo, Susann M. Brady-Kalnay
Publikováno v:
Diagnostics, Vol 11, Iss 2, p 181 (2021)
Background: We developed a fluorophore-conjugated peptide agent, SBK4, that detects a tumor-specific proteolyzed form of the cell adhesion molecule, PTPmu, found in the tumor microenvironment. We previously demonstrated its tissue specific distributi
Externí odkaz:
https://doaj.org/article/c5082f9692b9483f8e41c212191ca687
Autor:
Kelsey Herrmann, Bernadette O. Erokwu, Mette L. Johansen, James P. Basilion, Vikas Gulani, Mark A. Griswold, Chris A. Flask, Susann M. Brady-Kalnay
Publikováno v:
Translational Oncology, Vol 9, Iss 2, Pp 147-154 (2016)
Human brain tumors such as glioblastomas are typically detected using conventional, nonquantitative magnetic resonance imaging (MRI) techniques, such as T2-weighted and contrast enhanced T1-weighted MRI. In this manuscript, we tested whether dynamic
Externí odkaz:
https://doaj.org/article/198b4f5c7b244cb08227c02f3feea790
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5113 (2020)
Glioblastoma multiforme (GBM) is the most malignant primary brain cancer affecting adults. Therapeutic options for GBM have remained the same for over a decade with no significant improvement. Many therapies that are successful in culture have failed
Externí odkaz:
https://doaj.org/article/ea98ac0cdb884847b249221a345b9ec7
Molecular Imaging of Tumors Using a Quantitative T1 Mapping Technique via Magnetic Resonance Imaging
Autor:
Kelsey Herrmann, Mette L. Johansen, Sonya E. Craig, Jason Vincent, Michael Howell, Ying Gao, Lan Lu, Bernadette Erokwu, Richard S. Agnes, Zheng-Rong Lu, Jonathan K. Pokorski, James Basilion, Vikas Gulani, Mark Griswold, Chris Flask, Susann M. Brady-Kalnay
Publikováno v:
Diagnostics, Vol 5, Iss 3, Pp 318-332 (2015)
Magnetic resonance imaging (MRI) of glioblastoma multiforme (GBM) with molecular imaging agents would allow for the specific localization of brain tumors. Prior studies using T1-weighted MR imaging demonstrated that the SBK2-Tris-(Gd-DOTA)3 molecular
Externí odkaz:
https://doaj.org/article/4813a448bbc84f3db7529e66fc43a74c
Autor:
Mette L. Johansen, Jason Vincent, Haley Gittleman, Sonya E. L. Craig, Marta Couce, Andrew E. Sloan, Jill S. Barnholtz-Sloan, Susann M. Brady-Kalnay
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2372 (2019)
An integrated approach has been adopted by the World Health Organization (WHO) for diagnosing brain tumors. This approach relies on the molecular characterization of biopsied tissue in conjunction with standard histology. Diffuse gliomas (grade II to
Externí odkaz:
https://doaj.org/article/b81bbe8048fd459e91641409df3dc99f
Autor:
Susan M. Burden-Gulley, Theresa J. Gates, Adam M. Burgoyne, Jennifer L. Cutter, David T. Lodowski, Shenandoah Robinson, Andrew E. Sloan, Robert H. Miller, James P. Basilion, Susann M. Brady-Kalnay
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 4, Pp 305-316 (2010)
We recently found that normal human brain and low-grade astrocytomas express the receptor protein tyrosine phosphatase mu (PTPμ) and that the more invasive astrocytomas, glioblastoma multiforme (GBM), downregulate full-length PTPμ expression. Loss
Externí odkaz:
https://doaj.org/article/606a0ae2a73044899d838d194ce165b8
Autor:
Efstathios Karathanasis, Mark A. Griswold, James P. Basilion, Susann M. Brady-Kalnay, Christopher Hoimes, Ketan B. Ghaghada, Lisa Bauer, Shruti Shah, Ramamurthy Gopalakrishnan, Randall Toy, Elizabeth Doolittle, James Mcginnity, Aaron Abramowski, Pubudu M. Peiris
Glioblastoma multiforme is generally recalcitrant to current surgical and local radiotherapeutic approaches. Moreover, systemic chemotherapeutic approaches are impeded by the blood–tumor barrier. To circumvent limitations in the latter area, we dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9d92f85e90fe3f5fd7fc25be4de127
https://doi.org/10.1158/0008-5472.c.6507677
https://doi.org/10.1158/0008-5472.c.6507677
