Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Susann G. Schindler"'
Autor:
Virginia Lopez-Parra, Carlota Recio, Jesús Egido, Iolanda Lázaro, Susann G. Schindler, Beñat Mallavia, Oscar Lopez-Franco, Reinhard Depping, Ainhoa Oguiza, Guadalupe Ortiz-Muñoz, Carmen Gomez-Guerrero
Publikováno v:
The American Journal of Pathology. 182:1910-1921
Atherosclerosis is a chronic inflammatory disease of the arterial wall. NF-κB is a major regulator of inflammation that controls the expression of many genes involved in atherogenesis. Activated NF-κB was detected in human atherosclerotic plaques,
Autor:
Susann G. Schindler, Reinhard Depping, Holger Scholz, Charlotte Louise Justine Jacobi, Karin M. Kirschner
Publikováno v:
Cellular Physiology and Biochemistry. 29:223-232
Background/Aims: Wilms′ tumour protein, Wt1, is a zinc finger molecule, which is required for normal embryonic development. Mutations of the WT1 gene can give rise to childhood cancer of the kidneys. Different Wt1 isoforms exist, which function eit
Autor:
Daniel, Schraivogel, Susann G, Schindler, Johannes, Danner, Elisabeth, Kremmer, Janina, Pfaff, Stefan, Hannus, Reinhard, Depping, Gunter, Meister
Publikováno v:
Nucleic Acids Res. 43, 7447-7461 (2015)
Nucleic Acids Research
Nucleic Acids Research
MicroRNAs (miRNAs) guide Argonaute (Ago) proteins to distinct target mRNAs leading to translational repression and mRNA decay. Ago proteins interact with a member of the GW protein family, referred to as TNRC6A-C in mammals, which coordinate downstre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::97949ec6071604f221a47e6c4ca16234
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=46322
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=46322
Autor:
Roland H. Wenger, Susann G. Schindler, Anne K. Voss, Dörthe M. Katschinski, Tim Thomas, Lu Le
Publikováno v:
Cellular Physiology and Biochemistry. 14:351-360
Hypoxia-inducible factor (HIF) alpha subunits are induced under hypoxic conditions, when limited oxygen supply prevents prolyl hydroxylation-dependent binding of the ubiquitin ligase pVHL and subsequent proteasomal degradation. A short normoxic half-
Autor:
Dörthe M. Katschinski, Roland H. Wenger, Klaus F. Wagner, Luu Le, Thomas Hofer, Susann G. Schindler, Daniel A. Heinrich
Publikováno v:
Journal of Biological Chemistry. 277:9262-9267
Hypoxia-inducible factor (HIF)-1alpha is the oxygen-sensitive subunit of HIF-1, a transcriptional master regulator of oxygen homeostasis. Oxygen-dependent prolyl hydroxylation targets HIF-1alpha for ubiquitinylation and proteasomal degradation. Unexp
Pivotal Role of Reactive Oxygen Species as Intracellular Mediators of Hyperthermia-induced Apoptosis
Publikováno v:
Journal of Biological Chemistry. 275:21094-21098
The effects of cellular antioxidant capacity on hyperthermia (HT)-induced apoptosis and production of antiapoptotic heat shock proteins (HSPs) were investigated in HL-60 cells and in HL-60AR cells that are characterized by an elevated endogenous cata
Autor:
Joachim Fandrey, Utta Berchner-Pfannschmidt, Friederike Katharina Pientka, Jun Hu, Anika Thiel, Olaf Jöhren, Reinhard Depping, Susann G. Schindler, Britta Brix
Publikováno v:
Journal of Cell Science.
Hypoxia-inducible factors (HIFs) regulate more than 200 genes involved in cellular adaptation to reduced oxygen availability. HIFs are heterodimeric transcription factors that consist of one of three HIF-α subunits and a HIF-β subunit. Under normox
Autor:
Enno Hartmann, Matthias Köhler, Amrei Steinhoff, Eric Metzen, Riku Fagerlund, Beate Friedrich, Susann G. Schindler, Reinhard Depping
Publikováno v:
Biochimica et biophysica acta. 1783(3)
Hypoxia-inducible factors are the key elements in the essential process of oxygen homeostasis of vertebrate cells. Stabilisation and subsequent nuclear localisation of HIF-alpha subunits results in the activation of target genes such as vegf, epo and