Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Susann Friedel"'
Autor:
Anke Hinney, Thuy Trang Nguyen, André Scherag, Susann Friedel, Günter Brönner, Timo Dirk Müller, Harald Grallert, Thomas Illig, H-Erich Wichmann, Winfried Rief, Helmut Schäfer, Johannes Hebebrand
Publikováno v:
PLoS ONE, Vol 2, Iss 12, p e1361 (2007)
Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predisposing to obesity are not very well understood. We have performed a genome wide association study (GWA) for early onset (extreme) obesity.a) GWA (Genome
Externí odkaz:
https://doaj.org/article/2a7d08bec95e41248ea38afe291472bc
Autor:
Susann Friedel, Gudrun A. Rappold, Christine Fischer, Xavier Estivill, Max Endele, Johannes Kapeller, Stefan Ehrlich, Christian Hammer, Beate Niesler, Fernando Fernández-Aranda, Mònica Gratacòs, Anke Hinney, Manfred M. Fichter, Johannes Hebebrand
Publikováno v:
Pharmacogenetics and Genomics. 19:790-799
Objective As a key player in modulating both human physiological and behavioural functions including anxiety, perception and in particular appetite, serotonin (5-hydroxytryptamine, 5-HT) is likely to be involved in the aetiology of eating disorders.
Publikováno v:
Journal of Neural Transmission. 115:305-315
Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder among children and adolescents with high heritability. Molecular genetic findings support the thesis that dopaminergic, serotonergic, and noradrenergic neurotransmission
Autor:
Kerstin Koberwitz, Thomas Meitinger, Stefan Engeli, Susann Friedel, Peter Lichtner, Thuy Trang Nguyen, Kathrin Reichwald, Anke Hinney, Anne-Kathrin Wermter, Helmut Schäfer, Timo D. Müller, Johannes Hebebrand, Günter Brönner
Publikováno v:
Molecular Genetics and Metabolism. 90:429-434
Studies in rodent models demonstrated that the central cannabinoid receptor (Cnr1) mediates the orexigenic effects of cannabinoids. To analyze whether genetic variation in the cannabinoid receptor gene (CNR1) is implicated in human obesity, we initia
Autor:
Anke Hinney, Susann Friedel, Johannes Hebebrand, Astrid Dempfle, Benno G. Schimmelmann, Hanna Christiansen
Publikováno v:
Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie. 34:425-433
Zusammenfassung: Die Aufmerksamkeitsdefizit- und Hyperaktivitätsstörung (ADHS) ist mit einer Prävalenz von 3-7% eine häufige kinder- und jugendpsychiatrische Störung. Auf der Basis formalgenetischer Studien ergibt sich eine Heritabilitätsschät
Autor:
Johannes Hebebrand, H. Kiefl, Kerstin Konrad, U Knölker, Helmut Schäfer, Andreas Warnke, Kathrin Saar, Beate Herpertz-Dahlmann, Astrid Dempfle, Peter Nürnberg, Martin Linder, Helmut Remschmidt, U. Hemminger, Anke Hinney, Philip Heiser, Holger Thiele, Susann Friedel
Publikováno v:
Molecular Psychiatry. 11:196-205
Three groups have previously performed genome scans in attention-deficit/ hyperactivity disorder (ADHD); linkage to chromosome 5p13 was detected in all of the respective studies. In the current study, we performed a whole-genome scan with 102 German
Autor:
Frank Geller, Stefan A. Wudy, Johannes Hebebrand, Francisco Fontenla-Horro, Nadine Schäuble, Ludwig Gortner, Helmut Schäfer, Astrid Dempfle, Peter Lichtner, Helmut Remschmidt, Thomas Meitinger, Thomas Bettecken, Hai-Jun Wang, Anke Hinney, Susann Friedel, Sandra Hagemann, Klaus Huse
Publikováno v:
J. Clin. Endocrinol. Metab. 89, 157-162 (2004)
GH secretagogue receptor (GHSR, ghrelin receptor) is involved in regulation of body weight and GH secretion. We initially analyzed two single-nucleotide polymorphisms of the GHSR in up to 184 extremely obese children and adolescents and up to 184 hea
Publikováno v:
Biologie in unserer Zeit. 36:208-210
Das Netzwerk “Adipositas und assoziierte Storungen”, das seit 2001 als Bestandteil des Nationalen Genomforschungsnetzes (NGFN) durch das Bundesministerium fur Bildung und Forschung gefordert wird, beschaftigt sich mit den genetischen Ursachen der
Autor:
C. Wilhelm, C. I. Ganz Vogel, Tobias J. Renner, Anke Hinney, T. Trang Nguyen, Susanne Walitza, B. Herpertz-Dahlman, Helmut Schäfer, Haukur Palmason, M. Linder, Susann Friedel, Christine M. Freitag, Benno G. Schimmelmann, Kerstin Konrad, K.P. Lesch, Marcel Romanos, Judith Sinzig, Andreas Warnke, Astrid Dempfle, Johannes Hebebrand, Sascha Sauer, Jobst Meyer
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder of childhood onset. Clinical and biological evidence points to shared common central nervous system (CNS) pathology of ADHD and restless legs syndrome (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae08bf85f6303e0ba325faaac880b22b
https://www.zora.uzh.ch/id/eprint/14553/
https://www.zora.uzh.ch/id/eprint/14553/
Autor:
Johannes Hebebrand, Timo D. Müller, Susann Friedel, Brandon Greene, Helmut Schäfer, Iris M. Heid, Carla I. G. Vogel, Anke Hinney, André Scherag, H-Erich Wichmann, Harald Grallert, Thomas Illig
Publikováno v:
BMC Medical Genetics, Vol 10, Iss 1, p 14 (2009)
BMC Med. Genet. 10:14 (2009)
BMC Medical Genetics
BMC Med. Genet. 10:14 (2009)
BMC Medical Genetics
Background A recent genome-wide association (GWA) study of U.S. Caucasians suggested that eight single nucleotide polymorphisms (SNPs) in CTNNBL1 are associated with obesity and increased fat mass. We analysed the respective SNPs in data from our pre