Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Susann, Ludewig"'
Autor:
Danny Baltissen, Charlotte S. Bold, Lena Rehra, Marija Banićević, Justus Fricke, Jennifer Just, Susann Ludewig, Christian J. Buchholz, Martin Korte, Ulrike C. Müller
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The Tau protein can be phosphorylated by numerous kinases. In Alzheimer’s disease (AD) hyperphosphorylated Tau species accumulate as neurofibrillary tangles that constitute a major hallmark of AD. AD is further characterized by extracellular Aβ pl
Externí odkaz:
https://doaj.org/article/242ab636d58b405ca9545a37ecf5a283
Autor:
Susanne Erdinger, Irmgard Amrein, Michaela Back, Susann Ludewig, Martin Korte, Jakob von Engelhardt, David P. Wolfer, Ulrike C. Müller
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The amyloid precursor protein APP plays a crucial role in Alzheimer pathogenesis. Its physiological functions, however, are only beginning to be unraveled. APP belongs to a small gene family, including besides APP the closely related amyloid precurso
Externí odkaz:
https://doaj.org/article/ffbf24cb46bb4306b854fd2685dece4f
Autor:
Susann Ludewig, Leonie Salzburger, Alexander Goihl, Jana Rohne, Frank Leypoldt, Daniel Bittner, Emrah Düzel, Burkhart Schraven, Dirk Reinhold, Martin Korte, Péter Körtvélyessy
Publikováno v:
Cells, Vol 12, Iss 2, p 282 (2023)
Autoimmune encephalitis (AE) associated with autoantibodies against leucine-rich glioma-inactivated protein-1 (LGI1) can present with faciobrachial dystonic seizures (FBDS) and/or limbic encephalitis (LE). The reasons for this heterogeneity in phenot
Externí odkaz:
https://doaj.org/article/8e9dd7d9509b40e5b769d3c44285734c
Autor:
Syed Ahsan Raza, Anne Albrecht, Gürsel Çalışkan, Bettina Müller, Yunus Emre Demiray, Susann Ludewig, Susanne Meis, Nicolai Faber, Roland Hartig, Burkhart Schraven, Volkmar Lessmann, Herbert Schwegler, Oliver Stork
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Intra-hippocampal circuits are essential for associating a background context with behaviorally salient stimuli and involve cholinergic modulation at SST+ interneurons. Here the authors show that the salience of the background context memory is modul
Externí odkaz:
https://doaj.org/article/bb2ce21df8184b16927e262706f74ba5
Autor:
Körtvélyessy, Susann Ludewig, Leonie Salzburger, Alexander Goihl, Jana Rohne, Frank Leypoldt, Daniel Bittner, Emrah Düzel, Burkhart Schraven, Dirk Reinhold, Martin Korte, Péter
Publikováno v:
Cells; Volume 12; Issue 2; Pages: 282
Autoimmune encephalitis (AE) associated with autoantibodies against leucine-rich glioma-inactivated protein-1 (LGI1) can present with faciobrachial dystonic seizures (FBDS) and/or limbic encephalitis (LE). The reasons for this heterogeneity in phenot
Publikováno v:
The Neuroscientist
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
The Amyloid Precursor Protein (APP) is infamous for its proposed pivotal role in the pathogenesis of Alzheimer’s disease (AD). Much research on APP focusses on potential contributions to neurodegeneration, mostly based on mouse models with altered
Autor:
Charlotte Bold, Ulrike Müller, Kristin Metzdorf, Kristin Michaelsen-Preusse, Martin Korte, Susann Ludewig, Jennifer Just, Ulrike Herrmann
Publikováno v:
Proc Natl Acad Sci U S A
Alterations in Ca(2+) homeostasis have been reported in several in vitro and in vivo studies using mice expressing the Alzheimer’s disease–associated transgenes, presenilin and the amyloid precursor protein (APP). While intense research focused o
Autor:
David P. Wolfer, Lutz Slomianka, Susann Ludewig, Martin Korte, Kang Han, Dominique Fässler, Jakob von Engelhardt, Irmgard Amrein, Max Richter, Ulrike Müller, Michaela K Back, Susanne Erdinger, Vicky Steubler
Publikováno v:
The EMBO Journal, 40 (12)
e107471
The EMBO journal
England
The EMBO Journal
e107471
The EMBO journal
England
The EMBO Journal
The key role of APP for Alzheimer pathogenesis is well established. However, perinatal lethality of germline knockout mice lacking the entire APP family has so far precluded the analysis of its physiological functions for the developing and adult bra
Autor:
Roman Spilger, Susann Ludewig, Charlotte Bold, Karl Rohr, Danny Baltissen, Ulrike Müller, Martin Korte
A large body of evidence indicates a neuroprotective and neurotrophic function for APPs⍺ not only in vitro, but also when expressed by AAV vectors in vivo such as in APP/PS1 transgenic AD model mice with Aβ-induced pathology. Previously, we could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d42eb0f5b826ff96a5902d6b4f807754
https://doi.org/10.14293/s2199-1006.1.sor-.ppa6v3n.v1
https://doi.org/10.14293/s2199-1006.1.sor-.ppa6v3n.v1
Autor:
Ulrike Herrmann, Jakob von Engelhardt, Annika Mehr, Susann Ludewig, Martin Korte, David P. Wolfer, Meike Hick, Michaela Kerstin Müller, Ulrike Müller
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 30(7)
Amyloid-β precursor protein (APP) is central to the pathogenesis of Alzheimer’s disease, yet its physiological functions remain incompletely understood. Previous studies had indicated important synaptic functions of APP and the closely related hom