Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Susana Rojas-Tomé"'
Autor:
Miguel Hernández-Cerón, Víctor Chavarria, Camilo Ríos, Benjamin Pineda, Francisca Palomares-Alonso, Irma Susana Rojas-Tomé, Helgi Jung-Cook
Publikováno v:
Brain Sciences, Vol 13, Iss 6, p 869 (2023)
Glioblastoma is the most aggressive and lethal brain tumor in adults, presenting diffuse brain infiltration, necrosis, and drug resistance. Although new drugs have been approved for recurrent patients, the median survival rate is two years; therefore
Externí odkaz:
https://doaj.org/article/ed8c54b4f0c24fb78c195d98f76af8ed
Autor:
Nancy Monroy-Jaramillo, Pedro Dorado, Ingrid Fricke-Galindo, Irma Susana Rojas-Tomé, Marisol López-López, Alberto Ortega-Vázquez, Helgi Jung-Cook, Eva M Peñas-Lledó, Iris E. Martínez-Juárez, Adrián LLerena
Publikováno v:
Pharmacogenomics. 22:983-996
Aim: We evaluated the potential influence of genetic ( CYP3A5, EPHX1, NR1I2, HNF4A, ABCC2, RALBP1, SCN1A, SCN2A and GABRA1) and nongenetic factors on carbamazepine (CBZ) response, adverse drug reactions and CBZ plasma concentrations in 126 Mexican Me
Autor:
Patricia Rojas, Helgi Jung-Cook, Elizabeth Ruiz-Sánchez, Irma Susana Rojas-Tomé, Carolina Rojas, Arely M. López-Ramírez, Aldo Arturo Reséndiz-Albor
Publikováno v:
International journal of environmental research and public health. 19(23)
Increased life expectancy and high costs of medicines and medical care have led to the use of herbal products. However, these items may contain toxic compounds that have an impact on public health. We will focus on the regulatory aspects and differen
Autor:
Helgi Jung, Guadalupe Palencia Hernández, Iliana González Hernández, Dinora F. González-Esquivel, Guadalupe Concepción Vidal-Cantú, Irma Susana Rojas-Tomé, Nelly Castro, Francisca Pérez-Severiano, Verónica Pérez de la Cruz, Francisca Palomares-Alonso
Publikováno v:
Revista Brasileira de Farmacognosia. 30:251-256
Praziquantel is an anthelmintic drug extensively used that shows a low oral bioavailability. Various approaches have been used in order to increase the plasma levels of praziquantel, including the co-administration with Cytochrome P450 inhibitors. Mo
Autor:
Silvia Melchor-Doncel de la Torre, Rodrigo Aguayo-Ortiz, Francisca Palomares-Alonso, Iliana González-Hernández, Nelly Castro, Irma Susana Rojas-Tomé, Francisco Hernández-Luis, José Becerril-Vega, Laura Dominguez, Angélica González-Maciel, César A Rodríguez-Balderas, Sergio Rodríguez-Morales, Helgi Jung-Cook
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:1293-1300
Based on our previous research on cysticidal drugs, we report the synthesis and evaluation of three new benzimidazole derivatives. In these compounds, the amido group was used as a bioisosteric replacement of the ester group. The molecular docking on
Autor:
Iliana, González-Hernández, Francisca, Palomares-Alonso, José, Becerril-Vega, Silvia, Melchor-Doncel de la Torre, Francisco, Hernández-Luis, Sergio, Rodriguez-Morales, Rodrigo, Aguayo-Ortiz, Laura, Dominguez, César A, Rodríguez-Balderas, Angélica, González-Maciel, Irma Susana, Rojas-Tomé, Nelly, Castro, Helgi, Jung-Cook
Publikováno v:
Chemicalpharmaceutical bulletin. 67(12)
Based on our previous research on cysticidal drugs, we report the synthesis and evaluation of three new benzimidazole derivatives. In these compounds, the amido group was used as a bioisosteric replacement of the ester group. The molecular docking on
Akademický článek
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Akademický článek
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Autor:
Eva M Peñas-Lledó, Marisol López-López, Adrián LLerena, Helgi Jung-Cook, Iris E. Martínez-Juárez, Ingrid Fricke-Galindo, Irma Susana Rojas-Tomé, Alberto Ortega-Vázquez, Pedro Dorado, Nancy Monroy-Jaramillo
Publikováno v:
The pharmacogenomics journal. 20(6)
Genetic and nongenetic factors may contribute to lamotrigine (LTG) plasma concentration variability among patients. We simultaneously investigated the association of UGT1A1, UGT1A4, UGT2B7, ABCB1, ABCG2, and SLC22A1 variants, as well as antiepileptic
Autor:
Carmen Escalante-Membrillo, Ángeles Fernández, Dinora F. González-Esquivel, Irma Susana Rojas-Tomé, Nelly Castro, Helgi Jung Cook, Óscar Guerrero Garduño
Publikováno v:
Biomedical Chromatography. 30:933-937
Carbamazepine is an antiepileptic drug widely used for the treatment of epilepsy. In the National Institute of Neurology, monitoring has been performed using the technique chemiluminescent microparticle immunoassay (CMIA) in an automated way during t