Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Susana R. Parathath"'
Autor:
Bipin Bhatia, Susana R. Parathath, Adiba Ahmad, Zaher Nahlé, Anna Kenney, Andrey Korshunov, Cemile G. Guldal, Stefan M. Pfister, Aashir Awan, Lori A. Mainwaring, Massimo Squatrito
Publikováno v:
Acta Neuropathologica. 123:573-586
Development of the cerebellum occurs postnatally and is marked by a rapid proliferation of cerebellar granule neuron precursors (CGNPs). CGNPs are the cells-of-origin for SHH-driven medulloblastoma, the most common malignant brain tumor in children.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c46149256f96b1ac2fe696de7d840ce
https://doi.org/10.1007/s00401-012-0946-z
https://doi.org/10.1007/s00401-012-0946-z
Autor:
Susana R. Parathath, Dane Ohlosson Campbell, Lori A. Mainwaring, Anna Marie Kenney, Africa Fernandez-L
Publikováno v:
Development. 135:3291-3300
Sonic hedgehog (SHH) and insulin-like growth factor (IGF) signaling are essential for development of many tissues and are implicated in medulloblastoma, the most common solid pediatric malignancy. Cerebellar granule neuron precursors (CGNPs), propose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d2650d6c24ac71ce03f52dd3aa1963
https://doi.org/10.1242/dev.022871
https://doi.org/10.1242/dev.022871
Autor:
Africa Fernandez-L, Lori A. Mainwaring, Anna Marie Kenney, Cemile G. Guldal, Zaher Nahlé, Susana R. Parathath
Publikováno v:
Cell cycle (Georgetown, Tex.). 9(19)
Development of the cerebellum, a brain region regulating posture and coordination, occurs post-natally and is marked by rapid proliferation of granule neuron precursors (CGNPs), stimulated by mitogenic Sonic hedgehog (Shh) signaling. β-Arrestin (βA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62575c87fe45cf52df010399be845589
https://pubmed.ncbi.nlm.nih.gov/21057198
https://pubmed.ncbi.nlm.nih.gov/21057198
Publikováno v:
Stroke. 38(6)
Background and Purpose—Excitotoxicity is a component of many neurodegenerative diseases. The signaling events that lead from excitotoxic injury to neuronal death remain incompletely defined. Pharmacological approaches have shown that nitric oxide p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0481f960270e7d5241678a426f148fab
https://pubmed.ncbi.nlm.nih.gov/17446423
https://pubmed.ncbi.nlm.nih.gov/17446423
Publikováno v:
Journal of cell science. 119(Pt 2)
Stroke and many neurodegenerative diseases culminate in neuronal death through a mechanism known as excitotoxicity. Excitotoxicity proceeds through a complex signaling pathway that includes the participation of the serine protease tissue plasminogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b081bf19bd9c16c0c0888ada2b445ef
https://pubmed.ncbi.nlm.nih.gov/16410551
https://pubmed.ncbi.nlm.nih.gov/16410551
Publikováno v:
Cancer Research. 70:LB-13
Development of the cerbellum occurs primarily postnatally and is marked by a rapid proliferation of cerebellar granule neuron precursors (CGNPs). This proliferation requires the activity of the mitogen Sonic Hedgehog (Shh). The rapid proliferation st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df3d438c2ff3f4ffb559e6f5e480b52
https://doi.org/10.1158/1538-7445.am10-lb-13
https://doi.org/10.1158/1538-7445.am10-lb-13