Exploring wine yeast natural biodiversity to select strains with enological traits adapted to climate change

Autor: Joana P. Guedes, Tiago Vidal Cardoso, Ticiana Fernandes, Filipa Mendes, M. Margarida Baleiras-Couto, Filomena L. Duarte, Maria João Sousa, Ricardo Franco-Duarte, Susana R. Chaves, Manuela Côrte-Real

Publikováno v: Heliyon, Vol 10, Iss 18, Pp e36975- (2024)

Wine is widely consumed throughout the world and represents a significant financial market, but production faces increasing challenges. While consumers progressively value more complex flavor profiles, regional authenticity, and decreased use of addi

Externí odkaz: https://doaj.org/article/b247e591635e4b45a116db33c56ae383

Regulation of Cell Death Induced by Acetic Acid in Yeasts

Autor: Susana R. Chaves, António Rego, Vítor M. Martins, Cátia Santos-Pereira, Maria João Sousa, Manuela Côrte-Real

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Acetic acid has long been considered a molecule of great interest in the yeast research field. It is mostly recognized as a by-product of alcoholic fermentation or as a product of the metabolism of acetic and lactic acid bacteria, as well as of ligno

Externí odkaz: https://doaj.org/article/a2bb01e4a7c94212ae4cec9c9f7f001e

Cell wall dynamics modulate acetic acid-induced apoptotic cell death of Saccharomyces cerevisiae

Autor: António Rego, Ana Marta Duarte, Flávio Azevedo, Maria João Sousa, Manuela Côrte-Real, Susana R. Chaves

Publikováno v: Microbial Cell, Vol 1, Iss 9, Pp 303-314 (2014)

Acetic acid triggers apoptotic cell death in Saccharomyces cerevisiae, similar to mammalian apoptosis. To uncover novel regulators of this process, we analyzed whether impairing MAPK signaling affected acetic acid-induced apoptosis and found the mati

Externí odkaz: https://doaj.org/article/d299112a274b43f3b22543e8c6bc18e8

Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process

Autor: Manuela Côrte-Real, Filipa Mendes, Leslie Ann Silva Amaral, Maria João Sousa, Susana R. Chaves

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Cisplatin is a widely used antineoplastic agent that has DNA as the main target, though cellular resistance hampers its therapeutic efficacy. An emerging hallmark of cancer cells is their altered metabolism, characterized by increased glycolysis even

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5364b04042b19214cac9f6e1283c8d31
https://doi.org/10.1155/2020/4971525

Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae

Autor: Manuela Côrte-Real, Stéphen Manon, Lígia R. Rodrigues, Susana R. Chaves, Hernâni Gerós, Cátia Santos-Pereira, María T. Andrés, José F. Fierro

Publikováno v: International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, Elsevier, 2021, 171, pp.343-357. ⟨10.1016/j.ijbiomac.2020.12.224⟩
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

"Available online 07 January 2021"
Lactoferrin (Lf) is a bioactive milk-derived protein with remarkable wide-spectrum antifungal activity. To deepen our understanding of the molecular mechanisms underlying Lf cytotoxicity, the role of plasma mem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3632dc19750b7f540a9f18d569532a9d
https://hal.archives-ouvertes.fr/hal-03395479