Unilateral Corneal Insult Also Alters Sensory Nerve Activity in the Contralateral Eye

Autor: Carolina Luna, Susana Quirce, Adolfo Aracil-Marco, Carlos Belmonte, Juana Gallar, M. Carmen Acosta

Publikováno v: Frontiers in Medicine, Vol 8 (2021)

After the unilateral inflammation or nerve lesion of the ocular surface, the ipsilateral corneal sensory nerve activity is activated and sensitized, evoking ocular discomfort, irritation, and pain referred to the affected eye. Nonetheless, some patie

Externí odkaz: https://doaj.org/article/1ec639e0e56a47e1a8082e01cc54a621

Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion

Autor: Juana Gallar, M. C. Acosta, Kamila Mizerska, Víctor M. Meseguer, Susana Quirce, Carlos Belmonte, Carolina Luna

Publikováno v: Investigative Ophthalmology & Visual Science
Digital.CSIC. Repositorio Institucional del CSIC
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[Purpose]: To test the effect of different sodium channel blockers on the electrical activity of corneal nociceptors in intact and surgically injured corneas.
[Methods]: In anesthetized guinea pigs, a 4-mm diameter corneal flap was performed in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea71e02559a213a5a966c0bd5081197c
https://pubmed.ncbi.nlm.nih.gov/33393968

Melanopsin expression in the cornea

Autor: Russell N. Van Gelder, Andrea S. Bertke, Anton Delwig, David R. Copenhagen, S. Chaney, Todd P. Margolis, Jan Verweij, Cindy F. Yang, Juana Gallar, DeLaine D. Larsen, Ethan D. Buhr, Susana Quirce

Publikováno v: VISUAL NEUROSCIENCE, vol 35
Delwig, A; Chaney, SY; Bertke, AS; Verweij, J; Quirce, S; Larsen, DD; et al.(2018). Melanopsin expression in the cornea. VISUAL NEUROSCIENCE, 35. doi: 10.1017/S0952523817000359. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1zq6r7zh
VISUAL NEUROSCI
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
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A unique class of intrinsically photosensitive retinal ganglion cells in mammalian retinae has been recently discovered and characterized. These neurons can generate visual signals in the absence of inputs from rods and cones, the conventional photor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca70d75f21e5a93af0229f63d3ac4379
https://escholarship.org/uc/item/1zq6r7zh

Changes in sensory activity of ocular surface sensory nerves during allergic keratoconjunctivitis

Autor: Juana Gallar, Susana Quirce, Carolina Luna, M Carmen Acosta, Carlos Belmonte

Publikováno v: Pain. 154:2353-2362

Peripheral neural mechanisms underlying the sensations of irritation, discomfort, and itch accompanying the eye allergic response have not been hitherto analyzed. We explored this question recording the changes in the electrical activity of corneocon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe6472f12acdc9cd31246ba8d872a0e
https://doi.org/10.1016/j.pain.2013.07.012

New transient receptor potential TRPV1, TRPM8 and TRPA1 channel antagonists from a single linear β,γ-diamino ester scaffold

Autor: Roberto de la Torre-Martínez, M. Teresa Aranda, Antonio Ferrer-Montiel, Rosario González-Muñiz, Susana Quirce, Paula Pérez-Faginas, Asia Fernández-Carvajal

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Electronic supplementary information (ESI) available: Protocol for the evaluation of compound 4b in the CFA-induced paw inflammation model and obtained results. See DOI: 10.1039/c5ra25709c
A high throughput screening campaign identified nine b,g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbc6eb2d6d27e1ace7c1181d2d6e2e4
http://hdl.handle.net/10261/141530