Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Susana Proença"'
Autor:
Carolina Nunes, Susana Proença, Giovanna Ambrosini, David Pamies, Aurélien Thomas, Nynke I. Kramer, Marie-Gabrielle Zurich
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
For ethical, economical, and scientific reasons, animal experimentation, used to evaluate the potential neurotoxicity of chemicals before their release in the market, needs to be replaced by new approach methodologies. To illustrate the use of new ap
Externí odkaz:
https://doaj.org/article/0fbfdfac356046d09b4a042507af3896
Autor:
Manon C. Bouwmeester, Yu Tao, Susana Proença, Frank G. van Steenbeek, Roos-Anne Samsom, Sandra M. Nijmeijer, Theo Sinnige, Luc J. W. van der Laan, Juliette Legler, Kerstin Schneeberger, Nynke I. Kramer, Bart Spee
Publikováno v:
Molecules, Vol 28, Iss 2, p 621 (2023)
Emerging advances in the field of in vitro toxicity testing attempt to meet the need for reliable human-based safety assessment in drug development. Intrahepatic cholangiocyte organoids (ICOs) are described as a donor-derived in vitro model for disea
Externí odkaz:
https://doaj.org/article/8b733aeea46746d7985ffe97537d2bfb
Autor:
Sreya Ghosh, Jonathan De Smedt, Tine Tricot, Susana Proença, Manoj Kumar, Fatemeharefeh Nami, Thomas Vanwelden, Niels Vidal, Paul Jennings, Nynke I. Kramer, Catherine M. Verfaillie
Publikováno v:
Toxics, Vol 10, Iss 1, p 1 (2021)
Traditional toxicity risk assessment approaches have until recently focussed mainly on histochemical readouts for cell death. Modern toxicology methods attempt to deduce a mechanistic understanding of pathways involved in the development of toxicity,
Externí odkaz:
https://doaj.org/article/b65e0d4fa4854d86a69e42f53be3bb31
Autor:
Helena Lopes, Susana Proença
Publikováno v:
Applied Sciences, Vol 10, Iss 14, p 4951 (2020)
Since ashes are a possible source of Persistent Organic Pollutants (POPs) contamination, their application in soils must be subject to more study and control. In this scope, feed residual forest biomasses and biomass ashes, collected along one year i
Externí odkaz:
https://doaj.org/article/d37b9f3c084b4be1ab16baaa125258ec
Autor:
Sreya Ghosh, Jonathan De Smedt, Tine Tricot, Susana Proença, Manoj Kumar, Fatemeharefeh Nami, Thomas Vanwelden, Niels Vidal, Paul Jennings, Nynke I. Kramer, Catherine M. Verfaillie
Publikováno v:
Toxics
Toxics; Volume 10; Issue 1; Pages: 1
Toxics, Vol 10, Iss 1, p 1 (2022)
Toxics 10 (2020) 1
Ghosh, S, De Smedt, J, Tricot, T, Proença, S, Kumar, M, Nami, F, Vanwelden, T, Vidal, N, Jennings, P, Kramer, N I & Verfaillie, C M 2022, ' Hipsc-derived hepatocyte-like cells can be used as a model for transcriptomics-based study of chemical toxicity ', Toxics, vol. 10, no. 1, 1, pp. 1-18 . https://doi.org/10.3390/toxics10010001
Toxics, 10(1):1, 1-18. MDPI AG
Toxics, 10(1)
Toxics; Volume 10; Issue 1; Pages: 1
Toxics, Vol 10, Iss 1, p 1 (2022)
Toxics 10 (2020) 1
Ghosh, S, De Smedt, J, Tricot, T, Proença, S, Kumar, M, Nami, F, Vanwelden, T, Vidal, N, Jennings, P, Kramer, N I & Verfaillie, C M 2022, ' Hipsc-derived hepatocyte-like cells can be used as a model for transcriptomics-based study of chemical toxicity ', Toxics, vol. 10, no. 1, 1, pp. 1-18 . https://doi.org/10.3390/toxics10010001
Toxics, 10(1):1, 1-18. MDPI AG
Toxics, 10(1)
Traditional toxicity risk assessment approaches have until recently focussed mainly on histochemical readouts for cell death. Modern toxicology methods attempt to deduce a mechanistic understanding of pathways involved in the development of toxicity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f03abbbf3fa32b4ef5b41b4f622158
Autor:
Matilde Castro, Ana Sofia Fernandes, Susana Proença, Joana P. Miranda, Judite Costa, M. Fátima Cabral, Nuno G. Oliveira, Filipa Ramilo-Gomes, Rita C. Guedes, Bernardo Antunes
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5109 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 20
International Journal of Molecular Sciences
Volume 20
Issue 20
The role of metalloproteinases (MMPs) on the migration and invasion of cancer cells has been correlated with tumor aggressiveness, namely with the up-regulation of MMP-2 and 9. Herein, two pyridine-containing macrocyclic compounds, [15]pyN5 and [16]p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0d7e2a23d6ae38808220b24c2caae7
https://www.mdpi.com/1422-0067/20/20/5109
https://www.mdpi.com/1422-0067/20/20/5109
Autor:
Susana Proença, Alicia Paini, Andrew Worth, Jose Vicente Sala Benito, Elisabet Berggren, Maurice Whelan, Pilar Prieto, Elisabeth Joossens
Publikováno v:
ALTEX.
The Virtual Cell Based Assay (VCBA) is an in silico model that simulates the biokinetics of chemicals in in vitro test systems. Simulations by the VCBA can indicate the degree to which the bioavailable concentration varies across chemicals and experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1b216485ac367b372c597e9aeadcc6
https://doi.org/10.14573/altex.1812101
https://doi.org/10.14573/altex.1812101