Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Susana Moleirinho"'
Publikováno v:
AIMS Molecular Science, Vol 4, Iss 1, Pp 110-139 (2017)
The inflammatory response is the first line of defense against infectious agents or tissue damage. Innate immune cells are the crucial effectors regulating the different phase of inflammation. Their ability to timely develop an immune response is tig
Externí odkaz:
https://doaj.org/article/e5b85ba46c3846babbd82a737e2642e8
Autor:
Susana Moleirinho, Sany Hoxha, Vinay Mandati, Graziella Curtale, Scott Troutman, Ursula Ehmer, Joseph L Kissil
Publikováno v:
eLife, Vol 6 (2017)
The Hippo-YAP pathway is a central regulator of cell contact inhibition, proliferation and death. There are conflicting reports regarding the role of Angiomotin (Amot) in regulating this pathway. While some studies suggest a YAP-inhibitory function o
Externí odkaz:
https://doaj.org/article/54ca03b3344f4eaa95be9a5b5a8a8d5e
Autor:
Yanghua Wang MD, PhD, Adam Gersten MD, Susana Moleirinho PhD, Frank J. Gunn-Moore PhD, Paul A. Reynolds PhD, Michael B. Prystowsky MD, PhD
Publikováno v:
Academic Pathology, Vol 2 (2015)
We retrospectively studied the expression of Yes-associated protein (YAP) using immunohistochemical staining in 10 cases of head and neck squamous cell carcinoma with associated perineural invasion. We find that fibroblasts in areas associated with p
Externí odkaz:
https://doaj.org/article/421a4475da414f96a69af2cace74089c
Autor:
Susana Moleirinho, Calum Patrick, Andrew M Tilston-Lünel, Jennifer R Higginson, Liselotte Angus, Maciej Antkowiak, Susan C Barnett, Michael B Prystowsky, Paul A Reynolds, Frank J Gunn-Moore
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60028 (2013)
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional co-acti
Externí odkaz:
https://doaj.org/article/b708bafa4d894638aae7e83cb0c9537d
Autor:
Yohei Kitamura, Nobuhiko Kanaya, Susana Moleirinho, Wanlu Du, Clemens Reinshagen, Hikaru Sasaki, Khalid Shah
Publikováno v:
WFNOS 2022 Abstract Book.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adad1c61a6d0cc4463ce1633f630e72c
https://doi.org/10.14791/btrt.2022.10.f-2452
https://doi.org/10.14791/btrt.2022.10.f-2452
Publikováno v:
Neuro Oncol
Brain metastasis is associated with increased mortality in patients with cancer, 15-20% of patients will develop brain metastasis during the course of the disease. Characterizing clinically relevant brain metastasis models and exploring different opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1873757fbe4953c5f687958755e81b0
https://europepmc.org/articles/PMC7651636/
https://europepmc.org/articles/PMC7651636/
Autor:
Joana L. Mora, Jefferey L. Falcone, Hikaru Sasaki, Wanlu Du, Clemens Reinshagen, Nobuhiko Kanaya, Nada Attia, Priscilla Kaliopi Brastianos, Susana Moleirinho, Aldebaran M. Hofer, Esther Revai Lechtich, Khalid Shah, Agnieszka Bronisz, Arnaldo Franco, Yohei Kitamura
Publikováno v:
Science Advances
This study presents a mechanism-based receptor-targeted cellular therapy approach to treat breast to brain metastasis.
Basal-like breast cancer (BLBC) shows brain metastatic (BM) capability and overexpresses EGFR and death-receptors 4/5 (DR4/5);
Basal-like breast cancer (BLBC) shows brain metastatic (BM) capability and overexpresses EGFR and death-receptors 4/5 (DR4/5);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb05a794a70dba20ac77cebc1fa3b24
https://pubmed.ncbi.nlm.nih.gov/33658202
https://pubmed.ncbi.nlm.nih.gov/33658202
Publikováno v:
AIMS Molecular Science, Vol 4, Iss 1, Pp 110-139 (2017)
The inflammatory response is the first line of defense against infectious agents or tissue damage. Innate immune cells are the crucial effectors regulating the different phase of inflammation. Their ability to timely develop an immune response is tig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34eff071388becb99b200d46a1478a36
https://doi.org/10.3934/molsci.2017.1.110
https://doi.org/10.3934/molsci.2017.1.110
Autor:
Susana Moleirinho, Nicolas F. Schlecht, Harinder S. Hundal, Abigail Louise Dougal Chatterton, Paul A. Reynolds, Kathryn Haley, Yanhua Wang, Michael Prystowsky, Ailsa Watson, Andrew Tilston-Lunel, F. Gunn-Moore
Publikováno v:
Journal of Molecular Cell Biology. 8:439-455
AMT-L is supported by the School of Biology, University of St Andrews. AMT-L, PAR and FJGM were funded by the Anonymous Trust, University of St Andrews. PAR is supported by the Melville Trust for the Care and Cure of Cancer. The mass spectrometry wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7702930e124a6e22f488069e46ddc9
https://doi.org/10.1093/jmcb/mjw020
https://doi.org/10.1093/jmcb/mjw020
Metastatic brain tumors are the most commonly observed intracranial tumors, and 10–20% of adults with cancer develop brain metastasis. Characterizing clinically relevant brain metastasis models and exploring different delivery options to deliver dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6095e08f733b7efd0159680566ce111
https://europepmc.org/articles/PMC6216517/
https://europepmc.org/articles/PMC6216517/