Výsledky vyhledávání - "Susana L. González"

Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin-induced mechanical and thermal allodynia

Autor: M.V. Noya-Riobó, Marcelo J. Villar, Susana L. González, M.D. Recalde, C.A. Miguel, María Florencia Coronel

Publikováno v: Brain research. 1748

Chemotherapy-induced peripheral neuropathic pain (CIPNP) is a frequent and devastating side effect of cancer therapy. No preventive strategies are currently available. We investigated the use of resveratrol (RESV) in the prevention of CIPNP and evalu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3546dcfc8242e4c93bd889be0e829c7e
https://pubmed.ncbi.nlm.nih.gov/32866545

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Anti-allodynic and anti-inflammatory effects of 17alpha-hydroxyprogesterone caproate in oxaliplatin-induced peripheral neuropathy

Autor: María C. Raggio, Marcelo J. Villar, María Florencia Coronel, Susana L. González, Constanza Agata Miguel

Chemotherapy-induced peripheral neuropathy is a disabling condition induced by several frequently used chemotherapeutic drugs including the front-line agent oxaliplatin. Symptoms are predominantly sensory with the development of neuropathic pain. Alt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74cee6055ce81164312b8533f3f1c92
Wiley Online Library

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Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5α-reductase in the dorsal spinal cord of animals with neuropathic pain: Effects of progesterone administration

Autor: Maria Florencia Coronel, Florencia Labombarda, María L. Sánchez Granel, Natalia S. Adler, Susana L. González, María C. Raggio, Alejandro F. De Nicola

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of steroidogenic regulatory proteins and enzymes in the spinal cord suggests that neurosteroids

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02ce79c4f501ce53e2cd1424b47c9b5
https://doi.org/10.1016/j.neulet.2016.04.067

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Progesterone receptor-mediated actions and the treatment of central nervous system disorders: An up-date of the known and the challenge of the unknown

Autor: Susana L. González, Maria Florencia Coronel, Florencia Labombarda, María C. Raggio

Publikováno v: Steroids. 153:108525

Progesterone has been shown to exert a wide range of remarkable protective actions in experimental models of central nervous system injury or disease. However, the intimate mechanisms involved in each of these beneficial effects are not fully depicte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd3157a9e80d7c70e01eacbc6cbda69
https://doi.org/10.1016/j.steroids.2019.108525

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Allopregnanolone and progesterone in experimental neuropathic pain: former and new insights with a translational perspective

Autor: Maria Florencia Coronel, Christine Patte-Mensah, Susana L. González, María C. Raggio, Ayikoe Guy Mensah-Nyagan, Omar Taleb, Laurence Meyer

Publikováno v: Cellular and Molecular Neurobiology
Cellular and Molecular Neurobiology, Springer Verlag, 2019, 39 (4), pp.523-537. ⟨10.1007/s10571-018-0618-1⟩

In the last decades, an active and stimulating area of research has been devoted to explore the role of neuroactive steroids in pain modulation. Despite challenges, these studies have clearly contributed to unravel the multiple and complex actions an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e10d1c1c1402b18e70321e3af457f44
https://link.springer.com/article/10.1007/s10571-018-0618-

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Progesterone reduces the expression of spinal cyclooxygenase-2 and inducible nitric oxide synthase and prevents allodynia in a rat model of central neuropathic pain

Autor: Maria Florencia Coronel, Florencia Labombarda, Susana L. González, A. F. De Nicola

Publikováno v: European Journal of Pain. 18:348-359

Background Spinal cord injury (SCI) results in the development of chronic pain that is refractory to conventional treatment. Progesterone, a neuroprotective steroid, may offer a promising perspective in pain modulation after central injury. Here, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2452c4ca2d68ee91e3d766fdd1fc882
https://doi.org/10.1002/j.1532-2149.2013.00376.x

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Beyond reproduction: the role of progesterone in neuropathic pain after spinal cord injury

Autor: Maria Florencia Coronel, Susana L. González

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neural Regeneration Research, Vol 11, Iss 8, Pp 1238-1240 (2016)
Neural Regeneration Research

Fil: Gonzalez, Susana Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb79958ee5afaf30f09da1588b8bc16
http://www.nrronline.org/article.asp?issn=1673-5374

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Progesterone modulates pro-inflammatory cytokine expression profile after spinal cord injury: Implications for neuropathic pain

Autor: María C. Raggio, Susana L. González, Natalia S. Adler, Maria Florencia Coronel, Florencia Labombarda, Alejandro F. De Nicola

Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. Glial cell activation and cytokine production contribute to the pathology of central neuropathic syndromes. In this study we evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03c18619de0a7ff964d5009052b5d5e
https://www.sciencedirect.com/science/article/pii/S0165572816300133

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Neuroactive steroids, nociception and neuropathic pain: A flashback to go forward

Autor: Florencia Labombarda, María Florencia Coronel, Susana L. González

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The present review discusses the potential role of neurosteroids / neuroactive steroids in the regulation of nociceptive and neuropathic pain, and recapitulates the current knowledge on the main mechanisms involved in the reduction of pain, especiall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a974135b3c418f0d122117bdc19ce7
https://pubmed.ncbi.nlm.nih.gov/27091763

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Progesterone attenuates astro- and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury

Autor: Alejandro F. De Nicola, Florencia Labombarda, Rachida Guennoun, Paulina Roig, Michael Schumacher, Susana L. González, Analia Lima

Publikováno v: Experimental Neurology. 231:135-146

Reactive gliosis, demyelination and proliferation of NG2+ oligodendrocyte precursor cells (OPC) are common responses to spinal cord injury (SCI). We previously reported that short-term progesterone treatment stimulates OPC proliferation whereas chron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98c205899cd02a06cf80d694f1f7d86
https://doi.org/10.1016/j.expneurol.2011.06.001

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