Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Susana Geifman"'
Autor:
Deepti Sharma, Louis De Falco, Sivaraman Padavattan, Chang Rao, Susana Geifman-Shochat, Chuan-Fa Liu, Curt A. Davey
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The poly(ADP-ribose) polymerases play a key role in maintaining genomic integrity by detecting DNA damage and mediating repair. Here the authors characterize the kinetics of PARP1 binding to a variety of nucleosomes harbouring DNA double-strand break
Externí odkaz:
https://doaj.org/article/c4b2c946501c463c9cc98da888f89daf
Autor:
Jane Yi Lin Tan, Nagy A Habib, York Wieo Chuah, Yin Hoe Yau, Susana Geifman-Shochat, Wei Ning Chen
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123167 (2015)
MicroRNAs (miRNAs) are known to play a part in regulating important cellular processes. They generally perform their regulatory function through their binding with mRNAs, ultimately leading to a repression of target protein expression levels. However
Externí odkaz:
https://doaj.org/article/8888731e10db4835a872be898e77d305
Autor:
Christian Löw, Yin Hoe Yau, Els Pardon, Caroline Jegerschöld, Lisa Wåhlin, Esben M Quistgaard, Per Moberg, Susana Geifman-Shochat, Jan Steyaert, Pär Nordlund
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77984 (2013)
Mechanosensitive channels (MS) are integral membrane proteins and allow bacteria to survive sudden changes in external osmolarity due to transient opening of their pores. The efflux of cytoplasmic osmolytes reduces the membrane tension and prevents m
Externí odkaz:
https://doaj.org/article/3947c407b3fb436d8b9c27b3747ab996
Autor:
Jonathan How, Ai Zhang, Margaret Phillips, Aline Reynaud, Si Yan Lu, Lucy Xin Pan, Hai Ting Ho, Yin Hoe Yau, Albert Guskov, Konstantin Pervushin, Susana Geifman Shochat, Said Eshaghi
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53979 (2013)
STIM1 is a Ca(2+) sensor within the ER membrane known to activate the plasma membrane store-operated Ca(2+) channel upon depletion of its target ion in the ER lumen. This activation is a crucial step to initiate the Ca(2+) signaling cascades within v
Externí odkaz:
https://doaj.org/article/898795cd43ba4a56bbb39d25adce714d
Autor:
Tim Lauterbach, Manoj Manna, Maria Ruhnow, Yudi Wisantoso, Yaofeng Wang, Artur Matysik, Kamila Oglęcka, Yuguang Mu, Susana Geifman-Shochat, Thorsten Wohland, Rachel Kraut
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51222 (2012)
Organized assembly or aggregation of sphingolipid-binding ligands, such as certain toxins and pathogens, has been suggested to increase binding affinity of the ligand to the cell membrane and cause membrane reorganization or distortion. Here we show
Externí odkaz:
https://doaj.org/article/022d4581551f4390b7ba9b87e05cba98
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50490 (2012)
p97/Valosin-containing protein (VCP) is a member of the AAA-ATPase family involved in many cellular processes including cell division, intracellular trafficking and extraction of misfolded proteins in endoplasmic reticulum-associated degradation (ERA
Externí odkaz:
https://doaj.org/article/0f891cd2150f4e9e80051a53be1c41a9
Autor:
Nicole J Moreland, Moon Y F Tay, Elfin Lim, Prasad N Paradkar, Danny N P Doan, Yin Hoe Yau, Susana Geifman Shochat, Subhash G Vasudevan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 11, p e881 (2010)
BACKGROUND: The enzyme activities catalysed by flavivirus non-structural protein 3 (NS3) are essential for virus replication. They are distributed between the N-terminal protease domain in the first one-third and the C-terminal ATPase/helicase and nu
Externí odkaz:
https://doaj.org/article/051a3d034d624126913cd52bb6d25081
Autor:
Tan, Zhen Wei, Teo, Ziqiang, Tan, Carol, Choo, Chee Chong, Loo, Wei Sheng, Song, Yiyang, Tam, Zhi Yang, Ng, Sean Pin, Koh, Hong Zheng, Ng, Yi Siang, Shochat, Susana Geifman, Yau, Yin Hoe, Zhu, Pengcheng, Tan, Nguan Soon
Publikováno v:
In BBA - Molecular Cell Research October 2017 1864(10):1525-1536
Autor:
Chandramohanadas, Rajesh, Basappa, Russell, Bruce, Liew, Kingsley, Yau, Yin Hoe, Chong, Alvin, Liu, Min, Gunalan, Karthigayan, Raman, Rahul, Renia, Laurent, Nosten, Francois, Shochat, Susana Geifman, Dao, Ming, Sasisekharan, Ram, Suresh, Subra, Preiser, Peter
Publikováno v:
The Journal of Infectious Diseases, 2014 Nov . 210(10), 1616-1626.
Externí odkaz:
http://www.jstor.org/stable/43708248
Autor:
Zhang, Qian, Hunke, Cornelia, Yau, Yin Hoe, Seow, Vernon, Lee, Sumarlin, Tanner, Lukas Bahati, Guan, Xue Li **, Wenk, Markus R., Fibriansah, Guntur, Chew, Pau Ling, Kukkaro, Petra, Biuković, Goran, Shi, Pei-Yong, Shochat, Susana Geifman, Grüber, Gerhard, Lok, Shee-Mei
Publikováno v:
In Journal of Biological Chemistry 23 November 2012 287(48):40525-40534