Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Susana Dipp"'
Autor:
Zubaida Saifudeen, Jiao Liu, Susana Dipp, Xiao Yao, Yuwen Li, Nathaniel McLaughlin, Karam Aboudehen, Samir S El-Dahr
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44869 (2012)
Congenital reduction in nephron number (renal hypoplasia) is a predisposing factor for chronic kidney disease and hypertension. Despite identification of specific genes and pathways in nephrogenesis, determinants of final nephron endowment are poorly
Externí odkaz:
https://doaj.org/article/5c50b90e324a4f099cced84c903b7671
Autor:
Susana Dipp, T Tran
Publikováno v:
Journal of the Endocrine Society
Introduction: Maturity-onset diabetes of the young 5 (MODY-5) is a rare type of inherited diabetes mellitus. It is an autosomal dominant disease, manifesting as a clinically heterogeneous disorder with a lack of autoantibodies. On the molecular level
Autor:
Xiao Yao, Christine Bellew, Jana Stefkova, Samir S. El-Dahr, Shaowei Chen, Dimcho Bachvarov, Susana Dipp, Zubaida Saifudeen
Publikováno v:
Journal of Biological Chemistry. 286:32775-32789
Histone deacetylases (HDACs) regulate fundamental biological processes such as cellular proliferation, differentiation, and survival via genomic and nongenomic effects. This study examined the importance of HDAC activity in the regulation of gene exp
Publikováno v:
Advances in Therapy. 35:966-966
The article "Combination Glucose-Lowering Therapy Plans in T2DM: Case-Based Considerations".
Publikováno v:
Pediatric Research. 66:519-523
Kinins are vasoactive peptides that stimulate two G protein coupled bradykinin receptors (B1R and B2R). B2R-knockout (KO) mice are salt-sensitive and develop renal dysgenesis and hypertension if salt-stressed during embryogenesis. B1R-KO mice, on the
Publikováno v:
Journal of the American Society of Nephrology. 20:2328-2337
p53 is best known as a tumor suppressor that regulates cell-cycle, differentiation, and apoptosis pathways, but its potential role in embryonic development and organogenesis remains controversial. Here, p53(-/-) embryos bred on C57Bl6 background exhi
Autor:
Samir S. El-Dahr, Jana Stefkova, Susana Dipp, Virginia Diavolitsis, Hao Fan, Zubaida Saifudeen
Publikováno v:
Journal of Biological Chemistry. 280:23094-23102
p73 is a member of the p53 gene family, which also includes p53 and p63. These proteins share sequence similarity and target genes but also have divergent roles in cancer and development. Unlike p53, transcription of the p73 gene yields multiple full
Publikováno v:
Endocrine Practice. 22:6-7
Publikováno v:
Journal of Biological Chemistry. 278:34158-34166
Although p53 is known to have dual functions as a transcriptional activator and repressor, there has not been an example where both p53-activating and -repressing elements reside within one target promoter. Previous work from this laboratory defined
Publikováno v:
Endocrine Practice. 23:116