Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Susana Abreu"'
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 41, Iss 5, Pp 371-378 (2022)
Introduction: The use of mechanical circulatory support (MCS) in the pediatric population has evolved significantly in the past 20 years, but its management still poses several challenges. We aim to describe patient characteristics, outcomes, and mor
Externí odkaz:
https://doaj.org/article/ac8cd4925b52438a8050bc07bd073954
Autor:
Laurensia Yuniati, Angela Lauriola, Manouk Gerritsen, Susana Abreu, Eric Ni, Chiara Tesoriero, Jacob O. Onireti, Teck Yew Low, Albert J.R. Heck, Andrea Vettori, Timothy Cardozo, Daniele Guardavaccaro
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: Cullin-RING ligases (CRLs) control key cellular processes by promoting ubiquitylation of a multitude of soluble cytosolic and nuclear proteins. Subsets of CRL complexes are recruited and activated locally at cellular membranes; however, few
Externí odkaz:
https://doaj.org/article/787396060bef4facbcca34a0292af729
Autor:
Jana Sánchez-Wandelmer, Franziska Kriegenburg, Sabrina Rohringer, Martina Schuschnig, Rubén Gómez-Sánchez, Bettina Zens, Susana Abreu, Ralph Hardenberg, David Hollenstein, Jieqiong Gao, Christian Ungermann, Sascha Martens, Claudine Kraft, Fulvio Reggiori
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The protease Atg4 mediates Atg8 lipidation, required for autophagosome biogenesis, but also triggers Atg8 release from the membranes, however is unclear how these steps are coordinated. Here the authors show that phosphorylation by Atg1 inhibits Atg4
Externí odkaz:
https://doaj.org/article/0d25d8e1163b4f90ae02c9c439b13fba
Autor:
Michael A Kennedy, Kenneth Gable, Karolina Niewola-Staszkowska, Susana Abreu, Anne Johnston, Linda J Harris, Fulvio Reggiori, Robbie Loewith, Teresa Dunn, Steffany A L Bennett, Kristin Baetz
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004010 (2014)
Unbiased lipidomic approaches have identified impairments in glycerophosphocholine second messenger metabolism in patients with Alzheimer's disease. Specifically, we have shown that amyloid-β42 signals the intraneuronal accumulation of PC(O-16:0/2:0
Externí odkaz:
https://doaj.org/article/c7e06b2f45804822aea12b8b20a5a089
Autor:
ME Rahman Shuvo, Max Schwiening, Felipe Soares, Oliver Feng, Susana Abreu, Niki Veale, William Thomas, AA Roger Thompson, Richard J Samworth, Nicholas W Morrell, Stefan J Marciniak, Elaine Soon
ObjectivesSophisticated scores have been proposed for prognostication of mortality due to SARS-CoV-2 but perform inconsistently. We conducted these meta-analyses to uncover why and to pragmatically seek a single dependable biomarker for mortality.Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68af828211ee40d598ee0522661c1cd7
https://doi.org/10.1101/2022.12.03.22282974
https://doi.org/10.1101/2022.12.03.22282974
Publikováno v:
Psicologia, Saúde & Doença. 22:466-481
Fundacao para a Ciencia e Tecnologia e pelo Ministerio da Ciencia, Tecnologia e Ensino Superior, atraves de fundos nacionais e cofinanciado pelo FEDER atraves do COMPETE2020 no âmbito do Acordo de Parceria PT2020 (POCI-01-0145-FEDER-007653). Este tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14ef970039c597b5591f217a82758ff5
https://doi.org/10.15309/21psd220212
https://doi.org/10.15309/21psd220212
Autor:
Joseph E. Chambers, Nikita Zubkov, Markéta Kubánková, Jonathon Nixon-Abell, Ioanna Mela, Susana Abreu, Max Schwiening, Giulia Lavarda, Ismael López-Duarte, Jennifer A. Dickens, Tomás Torres, Clemens F. Kaminski, Liam J. Holt, Edward Avezov, James A. Huntington, Peter St George-Hyslop, Marina K. Kuimova, Stefan J. Marciniak
Publikováno v:
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
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Misfolding of secretory proteins in the endoplasmic reticulum (ER) features in many human diseases. In α1-antitrypsin deficiency, the pathogenic Z variant aberrantly assembles into polymers in the hepatocyte ER, leading to cirrhosis. We show that α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cc97a8f6c535f431275217bec99ecb
Autor:
Joseph E, Chambers, Nikita, Zubkov, Markéta, Kubánková, Jonathon, Nixon-Abell, Ioanna, Mela, Susana, Abreu, Max, Schwiening, Giulia, Lavarda, Ismael, López-Duarte, Jennifer A, Dickens, Tomás, Torres, Clemens F, Kaminski, Liam J, Holt, Edward, Avezov, James A, Huntington, Peter St, George-Hyslop, Marina K, Kuimova, Stefan J, Marciniak
Publikováno v:
Science advances. 8(14)
Misfolding of secretory proteins in the endoplasmic reticulum (ER) features in many human diseases. In α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78ff95963ee86c59ebea920b79abd7ca
https://pubmed.ncbi.nlm.nih.gov/35394846
https://pubmed.ncbi.nlm.nih.gov/35394846
Autor:
Annemarie van Schadewijk, Joseph E. Chambers, Stefan J. Marciniak, Pieter S. Hiemstra, Eimear N. Rutherford, Susana Abreu, Matthew O. Ellis, Jennifer A. Dickens
Publikováno v:
European Respiratory Journal, 59(1). EUROPEAN RESPIRATORY SOC JOURNALS LTD
BackgroundAlveolar epithelial cell dysfunction plays an important role in the pathogenesis of idiopathic pulmonary fibrosis (IPF), but remains incompletely understood. Some monogenic forms of pulmonary fibrosis are associated with expression of mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b7b9c031862deb0818b1ee64d92894
https://www.repository.cam.ac.uk/handle/1810/322467
https://www.repository.cam.ac.uk/handle/1810/322467
Autor:
Ribeiro, Susana Abreu, Vagnarelli, Paola, Dong, Yimin, Hori, Tetsuya, McEwen, Bruce F., Fukagawa, Tatsuo, Flors, Cristina, Earnshaw, William C., Groudine, Mark T.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2010 Jun 01. 107(23), 10484-10489.
Externí odkaz:
https://www.jstor.org/stable/25681809