Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Susana A Laucella"'
Autor:
María A Natale, Gonzalo Cesar, Maria G Alvarez, Melisa D Castro Eiro, Bruno Lococo, Graciela Bertocchi, María C Albareda, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007168 (2019)
[This corrects the article DOI: 10.1371/journal.pntd.0006998.].
Externí odkaz:
https://doaj.org/article/a4f83c4f25774bd2bad16fb1cf55a4eb
Autor:
Claudia Pengue, Gonzalo Cesar, María Gabriela Alvarez, Graciela Bertocchi, Bruno Lococo, Rodolfo Viotti, María Ailén Natale, Melisa D Castro Eiro, Silvia S Cambiazzo, Nancy Perroni, Myriam Nuñez, María Cecilia Albareda, Susana A Laucella
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218260 (2019)
Chronic inflammation, as a consequence of the persistent infection with Trypanosoma cruzi, leads to continuous activation of the immune system in patients with chronic Chagas disease. We have previously shown that increased sera levels of soluble P-s
Externí odkaz:
https://doaj.org/article/119c5d54b9ea49fca77448b54c8579b9
Autor:
María A Natale, Gonzalo Cesar, María G Alvarez, Melisa D Castro Eiro, Bruno Lococo, Graciela Bertocchi, María C Albareda, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0006998 (2018)
BackgroundThe severity of cardiac disease in chronic Chagas disease patients is associated with different features of T-cell exhaustion. Here, we assessed whether the ability of T cells to secrete IFN-γ in response to T. cruzi was linked to disrupti
Externí odkaz:
https://doaj.org/article/d293c8b24f0c41e68873f852c2eead89
Autor:
Damián E Pérez-Mazliah, Melisa D Castro Eiro, María Gabriela Álvarez, Bruno Lococo, Graciela Bertocchi, Gonzalo César, María A Natale, María C Albareda, Rodolfo Viotti, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006887 (2018)
BACKGROUND:Chronic infection with Trypanosoma cruzi leads to a constant stimulation of the host immune system. Monocytes, which are recruited in response to inflammatory signals, are divided into classical CD14hiCD16-, non-classical CD14loCD16+ and i
Externí odkaz:
https://doaj.org/article/160c3633ea1245b29e1e11f90c289243
Autor:
María G Alvarez, Graciela L Bertocchi, Gretchen Cooley, María C Albareda, Rodolfo Viotti, Damián E Perez-Mazliah, Bruno Lococo, Melisa Castro Eiro, Susana A Laucella, Rick L Tarleton
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 4, p e0004657 (2016)
BACKGROUND:Chagas disease is the highest impact parasitic disease in Latin America. We have proposed that changes in Trypanosoma cruzi-specific immune responses might serve as surrogate indicators of treatment success. Herein, we addressed in a long-
Externí odkaz:
https://doaj.org/article/564060fe26f548f9afa73f29c5fdbd37
Autor:
Rafael J Argüello, Carlos Vigliano, Patricia Cabeza-Meckert, Rodolfo Viotti, Fernando Garelli, Liliana E Favaloro, Roberto R Favaloro, Rubén Laguens, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e2989 (2014)
The main consequence of chronic Trypanosoma cruzi infection is the development of myocarditis in approximately 20-30% of infected individuals but not until 10-20 years after the initial infection. We have previously shown that circulating interferon-
Externí odkaz:
https://doaj.org/article/f1d5cae3887c49b48ee9e7380804b366
Autor:
María C Albareda, Ana M De Rissio, Gonzalo Tomas, Alicia Serjan, María G Alvarez, Rodolfo Viotti, Laura E Fichera, Mónica I Esteva, Daniel Potente, Alejandro Armenti, Rick L Tarleton, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2575 (2013)
BackgroundAdults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells. It is possibl
Externí odkaz:
https://doaj.org/article/a45df8bb769e448e918b841e2efa56f2
Autor:
Rafael J Argüello, María C Albareda, María G Alvarez, Graciela Bertocchi, Alejandro H Armenti, Carlos Vigliano, Patricia C Meckert, Rick L Tarleton, Susana A Laucella
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35966 (2012)
We had formerly demonstrated that subjects chronically infected with Trypanosoma cruzi show impaired T cell responses closely linked with a process of T cell exhaustion. Recently, the expression of several inhibitory receptors has been associated wit
Externí odkaz:
https://doaj.org/article/4380fbe367b345d9863e88ff821d22c5
Autor:
María G Alvarez, Miriam Postan, D Brent Weatherly, María C Albareda, John Sidney, Alessandro Sette, Carina Olivera, Alejandro H Armenti, Rick L Tarleton, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 9, p e288 (2008)
BACKGROUND:Previously, we identified a set of HLA-A020.1-restricted trans-sialidase peptides as targets of CD8+ T cell responses in HLA-A0201+ individuals chronically infected by T. cruzi. METHODS AND FINDINGS:Herein, we report the identification of
Externí odkaz:
https://doaj.org/article/ce57a62ff7ec41e1838ca0f175e0ec24
Autor:
Diana L Martin, D Brent Weatherly, Susana A Laucella, Melissa A Cabinian, Matthew T Crim, Susan Sullivan, Mark Heiges, Sarah H Craven, Charles S Rosenberg, Matthew H Collins, Alessandro Sette, Miriam Postan, Rick L Tarleton
Publikováno v:
PLoS Pathogens, Vol 2, Iss 8, p e77 (2006)
CD8+ T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of information from viral and bacterial infections, little is
Externí odkaz:
https://doaj.org/article/b2c7e5a9a5184f638ce4f01ad0897bf1