Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Susana A Laucella"'
Autor:
Melisa D. Castro Eiro, María A. Natale, María G. Alvarez, Araceli Castro, Débora Seigelshifer, Rodolfo Viotti, Marisa Fernández, Luis Mazzuoccolo, Bruno Lococo, Graciela L. Bertocchi, Gonzalo Cesar, María C. Albareda, María J. Elias, María B. Caputo, Eduardo Gaddi, Jeanette Balbaryski, Carlos A. Vigliano, Susana A. Laucella
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Dermatitis is the most common adverse event during treatment with benznidazole in chronic Chagas disease and is probably mediated by T cells. A set of molecules representative of the different type IV hypersensitivity reactions was evaluated
Externí odkaz:
https://doaj.org/article/fc9cdf3b60b54221970e33aec034c6a1
Autor:
Alina E. Perrone, Mariana Pinillo, Marcela S. Rial, Marisa Fernández, Natalia Milduberger, Carolina González, Patricia L. Bustos, Laura E. Fichera, Susana A. Laucella, María Cecilia Albareda, Jacqueline Bua
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11875 (2023)
Cyclophilins (CyPs) are a family of enzymes involved in protein folding. Trypanosoma cruzi, the causative agent of Chagas disease, has a 19-kDa cyclophilin, TcCyP19, that was found to be secreted in parasite stages of the CL Brener clone and recogniz
Externí odkaz:
https://doaj.org/article/327a1d97b16041009de3dceda3b3499b
Autor:
María Belén Caputo, Josefina Elias, Gonzalo Cesar, María Gabriela Alvarez, Susana Adriana Laucella, María Cecilia Albareda
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chagas disease, caused by the intracellular pathogen Trypanosoma cruzi, is the parasitic disease with the greatest impact in Latin America and the most common cause of infectious myocarditis in the world. The immune system plays a central role in the
Externí odkaz:
https://doaj.org/article/7e7c8f739fbb42abb72e4ccddbb4e870
Autor:
María Ailén Natale, Todd Minning, María Cecilia Albareda, Melisa Daiana Castro Eiro, María Gabriela Álvarez, Bruno Lococo, Gonzalo Cesar, Graciela Bertocchi, María Josefina Elias, María Belén Caputo, Rick Lee Tarleton, Susana Adriana Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009473 (2021)
In chronic Chagas disease, Trypanosoma cruzi-specific T-cell function decreases over time, and alterations in the homeostatic IL-7/IL-7R axis are evident, consistent with a process of immune exhaustion. IL-27 is an important immunoregulatory cytokine
Externí odkaz:
https://doaj.org/article/06691cc146b74fb197bcc2de737d9ef4
Autor:
Patricia L. Bustos, Natalia Milduberger, Bibiana J. Volta, Alina E. Perrone, Susana A. Laucella, Jacqueline Bua
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Trypanosoma cruzi is the protozoan unicellular parasite that causes Chagas disease. It can be transmitted from infected mothers to their babies via the connatal route, thus being able to perpetuate even in the absence of Triatomine insect vectors. Ch
Externí odkaz:
https://doaj.org/article/39bc0f0ceb2d4bb0a25844c9779b8628
Autor:
María A Natale, Gonzalo Cesar, Maria G Alvarez, Melisa D Castro Eiro, Bruno Lococo, Graciela Bertocchi, María C Albareda, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007168 (2019)
[This corrects the article DOI: 10.1371/journal.pntd.0006998.].
Externí odkaz:
https://doaj.org/article/a4f83c4f25774bd2bad16fb1cf55a4eb
Autor:
Claudia Pengue, Gonzalo Cesar, María Gabriela Alvarez, Graciela Bertocchi, Bruno Lococo, Rodolfo Viotti, María Ailén Natale, Melisa D Castro Eiro, Silvia S Cambiazzo, Nancy Perroni, Myriam Nuñez, María Cecilia Albareda, Susana A Laucella
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218260 (2019)
Chronic inflammation, as a consequence of the persistent infection with Trypanosoma cruzi, leads to continuous activation of the immune system in patients with chronic Chagas disease. We have previously shown that increased sera levels of soluble P-s
Externí odkaz:
https://doaj.org/article/119c5d54b9ea49fca77448b54c8579b9
Autor:
María A Natale, Gonzalo Cesar, María G Alvarez, Melisa D Castro Eiro, Bruno Lococo, Graciela Bertocchi, María C Albareda, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0006998 (2018)
BackgroundThe severity of cardiac disease in chronic Chagas disease patients is associated with different features of T-cell exhaustion. Here, we assessed whether the ability of T cells to secrete IFN-γ in response to T. cruzi was linked to disrupti
Externí odkaz:
https://doaj.org/article/d293c8b24f0c41e68873f852c2eead89
Autor:
Damián E Pérez-Mazliah, Melisa D Castro Eiro, María Gabriela Álvarez, Bruno Lococo, Graciela Bertocchi, Gonzalo César, María A Natale, María C Albareda, Rodolfo Viotti, Susana A Laucella
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006887 (2018)
BACKGROUND:Chronic infection with Trypanosoma cruzi leads to a constant stimulation of the host immune system. Monocytes, which are recruited in response to inflammatory signals, are divided into classical CD14hiCD16-, non-classical CD14loCD16+ and i
Externí odkaz:
https://doaj.org/article/160c3633ea1245b29e1e11f90c289243
Autor:
María C. Albareda, María A. Natale, Ana M. De Rissio, Marisa Fernandez, Alicia Serjan, María G. Alvarez, Gretchen Cooley, Huifeng Shen, Rodolfo Viotti, Jacqueline Bua, Melisa D. Castro Eiro, Myriam Nuñez, Laura E. Fichera, Bruno Lococo, Karenina Scollo, Rick L. Tarleton, Susana A. Laucella
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: In contrast to adults, Trypanosoma cruzi-infected children have more broadly functional Trypanosoma cruzi-specific T cells, and the total T-cell compartment exhibits fewer signs of immune exhaustion. However, not much is known about the l
Externí odkaz:
https://doaj.org/article/d3236f50cfb544b9b8a1c36dcdc49b6a