Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Susana, Roselló"'
Autor:
Loic Verlingue, Antoine Italiano, Hans Prenen, Eva Maria Guerra Alia, Diego Tosi, Ruth Perets, Iwona Lugowska, Vladimir Moiseyenko, Mahmut Gumus, Cagatay Arslan, Colin R. Lindsay, Sanjeev Deva, Álvaro Taus, Ana Oaknin, Sylvie Rottey, Irfan Cicin, Sema Sezgin Goksu, Alexey Smolin, Susana Roselló-Keränen, Christin Habigt, Daniel Marbach, Christophe Boetsch, David Dejardin, Nassim Sleiman, Stefan Evers, Muriel Richard, Caroline Ardeshir, Jehad Charo, Anton Kraxner, Volker Teichgräber, Nino Keshelava, Rafal Dziadziuszko
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105374- (2024)
Summary: Background: Simlukafusp alfa (FAP-IL2v) is an immune cytokine engineered to selectively promote immune responses in the tumour microenvironment. We evaluated the antitumour activity and safety of FAP-IL2v plus atezolizumab in recurrent and/o
Externí odkaz:
https://doaj.org/article/2eb15235333d4a14935f9abccb626cd2
Autor:
Federica Papaccio, Blanca García-Mico, Francisco Gimeno-Valiente, Manuel Cabeza-Segura, Valentina Gambardella, María Fernanda Gutiérrez-Bravo, Clara Alfaro-Cervelló, Carolina Martinez-Ciarpaglini, Pilar Rentero-Garrido, Sheila Zúñiga-Trejos, Juan Antonio Carbonell-Asins, Tania Fleitas, Susana Roselló, Marisol Huerta, Manuel M. Sánchez del Pino, Luís Sabater, Desamparados Roda, Noelia Tarazona, Andrés Cervantes, Josefa Castillo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background Patient-derived organoids (PDOs) from advanced colorectal cancer (CRC) patients could be a key platform to predict drug response and discover new biomarkers. We aimed to integrate PDO drug response with multi-omics characterizatio
Externí odkaz:
https://doaj.org/article/a72cfc5ee59741f4839fb4407bd9b3b0
Autor:
Parisi, Alessandro, Porzio, Giampiero, Cannita, Katia, Venditti, Olga, Avallone, Antonio, Filippi, Roberto, Salvatore, Lisa, Tortora, Giampaolo, Ribelli, Marta, Nigro, Olga, Gelsomino, Fabio, Spallanzani, Andrea, Zurlo, Valeria, Leo, Silvana, Dell'Aquila, Emanuela, Claudia, Fulgenzi, Lombardi, Pasquale, Keränen, Susana Roselló, Aimar, Giacomo, Depetris, Ilaria, Giampieri, Riccardo, Morelli, Cristina, De Tursi, Michele, Tinari, Nicola, Di Pietro, Francesca Romana, De Galitiis, Federica, Zanaletti, Nicoletta, Troiani, Teresa, Vitale, Pasquale, Garajova, Ingrid, Ghidini, Michele, Spinelli, Gian Paolo, Zoratto, Federica, Roberto, Michela, Ierino, Debora, Petrillo, Angelica, D'Orazio, Carla, Ficorella, Corrado, Cortellini, Alessio
Publikováno v:
In Clinical Colorectal Cancer December 2021 20(4):318-325
Autor:
Alessandro Parisi, Alessio Cortellini, Olga Venditti, Roberto Filippi, Lisa Salvatore, Giampaolo Tortora, Michele Ghidini, Olga Nigro, Fabio Gelsomino, Ina Valeria Zurlo, Claudia Fulgenzi, Pasquale Lombardi, Susana Roselló Keränen, Ilaria Depetris, Riccardo Giampieri, Cristina Morelli, Pietro Di Marino, Francesca Romana Di Pietro, Nicoletta Zanaletti, Pasquale Vitale, Ingrid Garajova, Gian Paolo Spinelli, Federica Zoratto, Michela Roberto, Angelica Petrillo, Giacomo Aimar, Leonardo Patruno, Carla D’Orazio, Corrado Ficorella, Claudio Ferri, Giampiero Porzio
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundFew data regarding post-induction management following first-line anti-epidermal growth factor receptor (EGFR)-based doublet regimens in patients with left-sided RAS/BRAF wild-type metastatic colorectal cancer (mCRC) are available.MethodsTh
Externí odkaz:
https://doaj.org/article/a4d272875d3649eb80da124a1aebeef6
Autor:
Manuel Cabeza-Segura, Valentina Gambardella, Francisco Gimeno-Valiente, Juan Antonio Carbonell-Asins, Lorena Alarcón-Molero, Arturo González-Vilanova, Sheila Zuñiga-Trejos, Pilar Rentero-Garrido, Rosana Villagrasa, Mireia Gil, Ana Durá, Paula Richart, Noelia Alonso, Marisol Huerta, Susana Roselló, Desamparados Roda, Noelia Tarazona, Carolina Martínez-Ciarpaglini, Josefa Castillo, Andrés Cervantes, Tania Fleitas
Publikováno v:
BRITISH JOURNAL OF CANCER
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Background Advanced gastro-oesophageal cancer (GEA) treatment has been improved by the introduction of immune checkpoint inhibitors (CPIs), yet identifying predictive biomarkers remains a priority, particularly in patients with a combined positive sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c0435ab96eb48406880f88f70a77f6
https://doi.org/10.1038/s41416-022-02005-z
https://doi.org/10.1038/s41416-022-02005-z
Autor:
Jose Martín-Arévalo, David Moro-Valdezate, Vicente Pla-Martí, Stephanie García-Botello, Leticia Pérez-Santiago, Pablo Moya-Marcos, Ana Izquierdo-Moreno, David Casado-Rodrigo, Susana Roselló-Keränen, Alejandro Espí-Macías
Purpose The main aim of this study was to identify a possible association between month of birth of colorectal cancer (CCR) patients and overall survival (OS) or disease-free survival (DFS). Methods This observational study included all consecutive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::234a4f80411b452d1e98ca66ddadd115
https://doi.org/10.21203/rs.3.rs-2769681/v1
https://doi.org/10.21203/rs.3.rs-2769681/v1
Autor:
Josep Tabernero, Anthony W. Tolcher, Eric Van Cutsem, Stephan Braun, Ivan D. Horak, Michael Kragh, Mikkel W. Pedersen, Rikke Hald, Ulla H. Hansen, Niels J.Ø. Skartved, Guillem Argilés, Rachel S. van der Post, Bastiaan B.J. Tops, Susana Roselló, Marta Benavent, Andrés Cervantes, Rocio Garcia-Carbonero, Amita Patnaik, Rodrigo Dienstmann
Figure legend to Supplementary Figure S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d189063a42e0a6e96b003b9ed5941a54
https://doi.org/10.1158/2159-8290.22530213.v1
https://doi.org/10.1158/2159-8290.22530213.v1
Autor:
Andrés Cervantes, Josep Tabernero, José Baselga, Premal Patel, Yibing Yan, Kui Lin, Raymond D. Meng, Sandra M. Sanabria Bohórquez, Wai Y. Chan, Michelle Nannini, Jin Zhu, Nageshwar Budha, Luna Musib, Juan Manuel Sanchis-García, Rafael Morales-Barrera, José Alejandro Pérez-Fidalgo, Teresa Macarulla, Mafalda Oliveira, Susana Roselló, Desamparados Roda, Cristina Saura
Supplementary Table S1. IC50 values of ipatasertib on cell viability in cell lines with or without alterations in PTEN or PIK3CA. Supplementary Table S2. Percent tumor growth inhibition (%TGI) in xenograft models with or without alterations in PTEN o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e4701c0f95763c34a048939d9dd118
https://doi.org/10.1158/2159-8290.22531864
https://doi.org/10.1158/2159-8290.22531864
Autor:
Josep Tabernero, Anthony W. Tolcher, Eric Van Cutsem, Stephan Braun, Ivan D. Horak, Michael Kragh, Mikkel W. Pedersen, Rikke Hald, Ulla H. Hansen, Niels J.Ø. Skartved, Guillem Argilés, Rachel S. van der Post, Bastiaan B.J. Tops, Susana Roselló, Marta Benavent, Andrés Cervantes, Rocio Garcia-Carbonero, Amita Patnaik, Rodrigo Dienstmann
Supplementary Table S2. Sym004 pharmacokinetic derived measures - dose-escalation and dose-expansion cohorts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68eedc090ea26524fb654211680e7005
https://doi.org/10.1158/2159-8290.22530204.v1
https://doi.org/10.1158/2159-8290.22530204.v1
Autor:
Josep Tabernero, Anthony W. Tolcher, Eric Van Cutsem, Stephan Braun, Ivan D. Horak, Michael Kragh, Mikkel W. Pedersen, Rikke Hald, Ulla H. Hansen, Niels J.Ø. Skartved, Guillem Argilés, Rachel S. van der Post, Bastiaan B.J. Tops, Susana Roselló, Marta Benavent, Andrés Cervantes, Rocio Garcia-Carbonero, Amita Patnaik, Rodrigo Dienstmann
Supplementary Figure S1. Pharmacokinetic profile of Sym004.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c982b1b7cb7cb0729c25487d194dd2e
https://doi.org/10.1158/2159-8290.22530210.v1
https://doi.org/10.1158/2159-8290.22530210.v1