Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan X. Hsiong"'
Autor:
David J. Mooney, R. Warren Sands, Kazuhisa Ouhara, Eduardo A. Silva, Toshihisa Kawai, Catia S. Verbeke, Susan X. Hsiong
Publikováno v:
Journal of Periodontology. 91:1475-1485
Background Periodontal disease results from the pathogenic interactions between the tissue, immune system, and microbiota; however, standard therapy fails to address the cellular mechanism underlying the chronic inflammation. Dendritic cells (DC) are
Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device
Autor:
Ying Zheng, Shuichi Takayama, Renny T. Franceschi, Yu Suke Torisawa, Nathaniel Huebsch, Susan X. Hsiong, Bor Han Chueh, David J. Mooney, Amy Y. Hsiao, Chunxi Ge
Publikováno v:
Biomedical Microdevices. 12:145-151
This paper describes a simple reversible hydrogel patterning method for 3D cell culture. Alginate gel is formed in select regions of a microfluidic device through light-triggered release of caged calcium. In the pre-gelled alginate solution, calcium
Publikováno v:
Tissue Engineering Part A. 15:263-272
The role of morphogens in bone regeneration has been widely studied, whereas the effect of matrix cues, particularly on stem cell differentiation, are less well understood. In this work, we investigated the effects of arginine-glycine-aspartate (RGD)
Autor:
Hyunjoon Kong, David J. Mooney, Susan X. Hsiong, Claudia Fischbach, Will Yuen, Marta B. Evangelista
Publikováno v:
Proceedings of the National Academy of Sciences. 106:399-404
Three-dimensional culture alters cancer cell signaling; however, the underlying mechanisms and importance of these changes on tumor vascularization remain unclear. A hydrogel system was used to examine the role of the transition from 2D to 3D culture
Autor:
Susan X. Hsiong, Peter H. Cooke, Maria Ericsson, David J. Mooney, Hyunjoon Kong, Marshall L. Fishman
Publikováno v:
Macromolecular Bioscience. 8:469-477
Several high-resolution imaging techniques such as FESEM, TEM and AFM are compared with respect to their application on alginate hydrogels, a widely used polysaccharide biomaterial. A new AFM method applicable to RGD peptides covalently conjugated to
Autor:
Cristina C. Barrias, Rui Loja Fernandes, David J. Mooney, Marta B. Evangelista, Hyunjoon Kong, Pedro L. Granja, Susan X. Hsiong, Paula Sampaio, Mário A. Barbosa, Roberto Salema
Publikováno v:
Biomaterials. 28:3644-3655
There is a need for new therapeutic strategies to treat bone defects caused by trauma, disease or tissue loss. Injectable systems for cell transplantation have the advantage of allowing the use of minimally invasive surgical procedures, and thus for
Publikováno v:
Nano Letters. 7:161-166
It is hypothesized that the nanoscale organization of cell adhesion ligands in a synthetic ECM regulates non-viral gene delivery. This hypothesis was examined with pre-osteoblasts cultured on substrates which present varied density and spacing of syn
Publikováno v:
Tissue Engineering. 12:2425-2433
The close apposition of osteoblasts and chondrocytes in bone and their interaction during bone development and regeneration suggest that they may each regulate the other's growth and differentiation. In these studies, osteoblasts and chondrocytes wer
Autor:
Susan X. Hsiong, David J. Mooney
Publikováno v:
Periodontology 2000. 41:109-122
Publikováno v:
Biomaterials. 26:303-310
Multipotent cell types are rapidly becoming key components in a variety of tissue engineering schemes, and mesenchymal stem cells (MSCs) are emerging as an important tool in bone tissue regeneration. Although several soluble signals influencing osteo